Abstract: A method and system for correcting vision in an eye that uses a wavefront-customized phakic or pseudophakic Intraocular Lens (IOL), the method comprising: (1) measuring wavefront aberrations of the eye; (2) designing a wavefront-customized correction profile for an IOL; (3) creating a customized IOL with the customized correction profile; and (4) implanting the customized IOL in the eye, without having to remove the natural lens. Alternatively, an uncorrected IOL is implanted first, followed by scanning a femtosecond laser spot across the implanted IOL to locally change the Index of Refraction of the IOL material and create an in-situ customized IOL.

Abstract: This invention relates to methods and devices for designing customized contact lenses, by initially making dynamic wavefront sensor measurements through a trial contact lens that is fitted on an eye, and then calculating a WaveFront Guided (WFG) correction to be applied to the trial contact lens that reduces the RMS level of aberrations as much as practically possible. The output of the wavefront correction program is a customized lathe file that the manufacturer can use to make customized contact lenses on a lathe. The method works best for soft contact lenses and scleral lenses.

Abstract: Methods for the rapid detection of the presence or absence of Hepatitis B Virus (HBV) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, competitive blocking oligonucleotides, and probes targeting HBV (in particular HBV RNA, in particular, HBV RNA transcribed from cccDNA, such as pgRNA) and kits are provided that are designed for the detection of HBV (in particular HBV RNA, in particular, HBV RNA transcribed from cccDNA, such as pgRNA).

Abstract: A method and system for correcting vision in an eye that uses a wavefront-customized phakic or pseudophakic Intraocular Lens (IOL), the method comprising: (1) measuring wavefront aberrations of the eye; (2) designing a wavefront-customized correction profile for an IOL; (3) creating a customized IOL with the customized correction profile; and (4) implanting the customized IOL in the eye, without having to remove the natural lens. Alternatively, an uncorrected IOL is implanted first, followed by scanning a femtosecond laser spot across the implanted IOL to locally change the Index of Refraction of the IOL material and create an in-situ customized IOL.

Abstract: This invention relates to methods and devices for designing customized contact lenses, by initially making dynamic wavefront sensor measurements through a trial contact lens that is fitted on an eye, and then calculating a WaveFront Guided (WFG) correction to be applied to the trial contact lens that reduces the RMS level of aberrations as much as practically possible. The output of the wavefront correction program is a customized lathe file that the manufacturer can use to make customized contact lenses on a lathe. The method works best for soft contact lenses and scleral lenses.

Abstract: A method and device are provided for detecting and determining a type of a coating on either surface of a transparent sheet, measuring a thickness of the transparent sheet and measuring a spacing between at least two transparent sheets. The method and device include at least three discrete light sources, a 2D image generating device, a lens, and a processor. A reflected image area from the surfaces of the transparent sheet from each of the at least three discrete light sources produces a sparse spectrometer profile used to detect the coating and to determine the type of coating on either surface of the transparent sheet. A distance between the reflected image position from the at least three discrete light sources from both surfaces of the transparent sheet is used to calculate the thickness of the transparent sheet and the spacing between at least two transparent sheets.

Abstract: A method and device are provided for detecting and determining a type of a coating on either surface of a transparent sheet, measuring a thickness of the transparent sheet and measuring a spacing between at least two transparent sheets. The method and device include at least three discrete light sources, a 2D image generating device, a lens, and a processor. A reflected image area from the surfaces of the transparent sheet from each of the at least three discrete light sources produces a sparse spectrometer profile used to detect the coating and to determine the type of coating on either surface of the transparent sheet. A distance between the reflected image position from the at least three discrete light sources from both surfaces of the transparent sheet is used to calculate the thickness of the transparent sheet and the spacing between at least two transparent sheets.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: An intra-oral laser digitizer system provides a three-dimensional visual image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period. The intra-oral digitizer may be inserted into an oral cavity (in vivo) to capture an image of a dental item such as a tooth, multiple teeth or dentition. The captured image is processed to generate the three-dimension visual image.

Abstract: An intra-oral laser digitizer system provides a three-dimensional visual image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period. The intra-oral digitizer may be inserted into an oral cavity (in vivo) to capture an image of a dental item such as a tooth, multiple teeth or dentition. The captured image is processed to generate the three-dimension visual image.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: An intra-oral laser digitizer system provides a three-dimensional visual image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period. The intra-oral digitizer may be inserted into an oral cavity (in vivo) to capture an image of a dental item such as a tooth, multiple teeth or dentition. The captured image is processed to generate the three-dimension visual image.

Abstract: A intra-oral laser digitizer system provides a three-dimensional visual image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period. The intra-oral digitizer may be inserted into an oral cavity (in vivo) to capture an image of a dental item such as a tooth, multiple teeth or dentition. The captured image is processed to generate the three-dimension visual image.

Abstract: A laser digitizer system provides a visual three-dimensional image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period.

Abstract: A digitized image of an object may include representations of portions of the object that are obscured, occluded or otherwise unobservable. The image may be a multi-dimensional visual representation of dentition. Characteristics of the dentition and its surfaces, contours, and shape may be determined and/or analyzed. A light may be directed toward and reflected from the dentition. The reflected light may be combined with a reference to determine characteristics of the dentition, including obscured areas such as subgingival tissue.

Abstract: A intra-oral laser digitizer system provides a three-dimensional visual image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period. The intra-oral digitizer may be inserted into an oral cavity (in vivo) to capture an image of a dental item such as a tooth, multiple teeth or dentition. The captured image is processed to generate the three-dimension visual image.

Abstract: A laser digitizer system provides a visual three-dimensional image of a real-world object such as a dental item through a laser digitization. The laser digitizer captures an image of the object by scanning multiple portions of the object in an exposure period.