Abstract: To train a machine learning algorithm to identify DNA sequences, an electrochemical sensor detects a set of electrical signals from each of a plurality of standards each representing a known sequence. A computing device obtains the sets of electrical signals and trains a machine learning model to identify a sequence using, for each of the standards, (i) characteristics of the set of electrical signals, and (ii) the known sequence of the standard. The electrochemical sensor detects a set of electrical signals from a DNA sequence from a patient having an unknown sequence. The computing device obtains the set of electrical signals from the patient DNA sequence and applies characteristics of the set of electrical signals from the patient DNA sequence to the trained machine learning model to identify a sequence for the patient DNA sequence.

Abstract: Measuring of the binding of a transcription factor (using, for example, chromatin immunoprecipitation) according to the present invention is provides an improved marker for a disease. These markers can be used in diagnostics for diseases where a transcription factor binding event plays a role. Additionally, they can be used to adjust disease risk profiles for healthy individuals as with typical genetic variants.

Abstract: Measuring of the binding of a transcription factor (using, for example, chromatin immunoprecipitation) according to the present invention is provides an improved marker for a disease. These markers can be used in diagnostics for diseases where a transcription factor binding event plays a role. Additionally, they can be used to adjust disease risk profiles for healthy individuals as with typical genetic variants.

Abstract: Measuring of the binding of a transcription factor (using, for example, chromatin immunoprecipitation) according to the present invention is provides an improved marker for a disease. These markers can be used in diagnostics for diseases where a transcription factor binding event plays a role. Additionally, they can be used to adjust disease risk profiles for healthy individuals as with typical genetic variants.

Abstract: A system and method for navigating relationships between beans using filters and container managed relationships are provided. With the system and method, filters are specified in the relationship definition of a deployment descriptor of a bean. The filters generate additional predicates to the WHERE clauses in SQL SELECT statements generated based on the contents of the deployment descriptor. Moreover, these filters may be defined such that method parameters may be passed into the resulting deployed code to thereby make them more flexible. Therefore, with the system and method, rather than defining filters programmatically in methods of a bean's implementation class, filters are defined declaratively in the deployment descriptor of the bean. Since these filters are specified in the deployment descriptor of the bean, they are accessible to clients of the bean through the local interface.

Abstract: Mapping Enterprise Java Bean (“EJB”) attributes to database schema including providing a first metamap including one or more abstracted variable characteristics of a first database schema and creating from the first metamap a second metamap for a second database schema including varying one or more of the abstracted variable characteristics to conform to the second database schema. Typical embodiments also include synchronizing, in response to methods invoked on the EJB and in dependence upon the second metamap, the state of the EJB with a persistent data store having the second database schema. In typical embodiments, synchronizing the state of the EJB with a persistent data store having the second database schema also includes creating records, updating records, and deleting records in the persistent data store.

Abstract: A rock bolt load sensor assembly for use to determine the load on a nut screwed onto a bolt embedded in a rock face, the assembly comprising a plurality of spring washers arranged to be mounted on the bolt between the nut and a roof plate, and a sensor comprising an induction coil adapted to be, in use, placed around the washers, the sensor including an indicator coupled to the induction coil whereby in use, the spring washers define an air space which varies in dependence on the load on the bolt and the induction coil provides an electrical indication of variation of the air space and the indicator provides an indication of variation of the load on the bolt.

Abstract: Particles are fed for sorting by a radial distributor having an upper surface on which the particles gradually spread arcuately and are displaced radially outwardly, by for example vibration of the distributor, to a lip of the upper surface where they define one or more curved arrays as the fall over the lip. As they fall in free flight trajectory paths the particles present a curved array one particle deep to a separating device arranged to sort the particles according to the degree they possess a particular characteristic.

Abstract: Selection means is provided for particles following a free flight trajectory path, those particles having a preselected characteristic, such as fluorescence under x-ray bombardment, being detected and a signal being transmitted on such detection to electrostatic charging means to locally ionize the atmosphere and thereby charge the detected particle as it passes through the locally ionized atmosphere, the charged particle being deflected from its free flight trajectory path by an electric field. Non-detected and uncharged particles continue in the free flight trajectory path. Particles may be detected in a path having lateral spread by providing detecting means and electrostatic charging means which are together responsive to particles in respective portions of the path.

Abstract: Method and apparatus for sorting objects according to the degree to which they possess a required characteristic. Objects are moved in a line on a conveyor belt past a line of detectors each responsive to the required characteristic. Each detector produces a time sequence of output signals and the signals from successive detectors are accumulated. The objects are projected from the downstream end of the conveyor belt in a free flight path past an optical scanner and a series of air blast nozzles. The scanner determines the portions and sizes of the objects and objects selected on a comparison of the detector signals and signals from the scanner are blasted with air jets from appropriate nozzles so as to be deflected from their free flight trajectory. Deflected and undeflected objects are caught in separate collection bins.