Patents by Inventor Alan Bruce Montgomery

Alan Bruce Montgomery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10471083
    Abstract: The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: November 12, 2019
    Assignee: SAVARA INC.
    Inventor: Alan Bruce Montgomery
  • Patent number: 10406171
    Abstract: The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: September 10, 2019
    Assignee: SAVARA INC.
    Inventor: Alan Bruce Montgomery
  • Publication number: 20170296562
    Abstract: The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator.
    Type: Application
    Filed: November 7, 2016
    Publication date: October 19, 2017
    Inventor: Alan Bruce Montgomery
  • Publication number: 20170296517
    Abstract: A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam, or a pharmaceutically acceptable salt thereof, delivered as an aerosol or dry powder formulation.
    Type: Application
    Filed: November 15, 2016
    Publication date: October 19, 2017
    Inventor: Alan Bruce Montgomery
  • Patent number: 9533000
    Abstract: A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam, or a pharmaceutically acceptable salt thereof, delivered as an aerosol or dry powder formulation.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: January 3, 2017
    Assignee: GILEAD SCIENCES, INC.
    Inventor: Alan Bruce Montgomery
  • Patent number: 9526695
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: December 27, 2016
    Assignee: CARDEAS PHARMA CORPORATION
    Inventor: Alan Bruce Montgomery
  • Patent number: 9526696
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: December 27, 2016
    Assignee: CARDEAS PHARMA CORPORATION
    Inventor: Alan Bruce Montgomery
  • Patent number: 9526697
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: December 27, 2016
    Assignee: CARDEAS PHARMA CORPORATION
    Inventor: Alan Bruce Montgomery
  • Patent number: 9526698
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: December 27, 2016
    Assignee: CARDEAS PHARMA CORPORATION
    Inventor: Alan Bruce Montgomery
  • Patent number: 9486462
    Abstract: The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: November 8, 2016
    Assignee: CARDEAS PHARMA CORPORATION
    Inventor: Alan Bruce Montgomery
  • Publication number: 20160143932
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: February 1, 2016
    Publication date: May 26, 2016
    Inventor: Alan Bruce Montgomery
  • Publication number: 20160143933
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: February 1, 2016
    Publication date: May 26, 2016
    Inventor: Alan Bruce Montgomery
  • Publication number: 20160143847
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: February 1, 2016
    Publication date: May 26, 2016
    Inventor: Alan Bruce Montgomery
  • Publication number: 20160143931
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: February 1, 2016
    Publication date: May 26, 2016
    Inventor: Alan Bruce Montgomery
  • Publication number: 20150057242
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: September 8, 2014
    Publication date: February 26, 2015
    Inventor: ALAN BRUCE MONTGOMERY
  • Publication number: 20150057241
    Abstract: The present invention is synergistic antibiotic compositions having pH adjusted profiles for manufacturing combination, and administration, particularly for patients at risk or suffering from ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic compositions containing fosfomycin and aminoglycosides having individually predetermined and selected pH ranges are manufactured and stored for in combination prior to aerosolization, preferably with a specially designed in-line nebulizer attached to a ventilator.
    Type: Application
    Filed: August 26, 2014
    Publication date: February 26, 2015
    Inventor: Alan Bruce Montgomery
  • Patent number: 8841286
    Abstract: A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry powder formulation.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: September 23, 2014
    Assignee: Gilead Sciences, Inc.
    Inventor: Alan Bruce Montgomery
  • Patent number: 8826904
    Abstract: The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 9, 2014
    Assignee: Cardeas Pharma Corporation
    Inventor: Alan Bruce Montgomery
  • Patent number: 8820323
    Abstract: The present invention is antibiotic compositions, ventilator-based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator-associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an inline nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: September 2, 2014
    Assignee: Cardeas Pharma Corporation
    Inventor: Alan Bruce Montgomery
  • Publication number: 20140221302
    Abstract: The present invention is antibiotic compositions, ventilator based systems and methods relating to ventilator-associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis. Antibiotic combinations of fosfomycin and an aminoglycoside, preferably amikacin, are administered via an in-line nebulizer within the airway of the ventilator. Humidified conditions create an improved aerosol mist to treat VAP and VAT.
    Type: Application
    Filed: July 12, 2012
    Publication date: August 7, 2014
    Applicant: Cardeas Pharma, Inc.
    Inventor: Alan Bruce Montgomery