Patents by Inventor Alan C. Moss

Alan C. Moss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease
    Patent number: 10266895
    Abstract: The present disclosure relates to methods of collecting intestinal luminal fluid (ILF) exosomes and microvesicles (EMV) and isolating corresponding mRNA in order to diagnose and treat inflammatory bowel diseases (IBD). In particular, certain embodiments relate to the method of capturing EMV from ILF applied to a filter device that is capable of capturing EMV. Nucleic acids such as mRNA can be isolated from the EMV using an oligo(dT)-coated plate designed to accommodate the filter device and then used for further molecular analysis. Quantification of the collected nucleic acids may then be used in the diagnosis and/or treatment of IBD.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: April 23, 2019
    Assignees: Hitachi Chemical Company Ltd., Hitachi Chemical Co. America, Ltd., Beth Israel Deaconess Medical Center
    Inventors: Masato Mitsuhashi, Alan C. Moss
  • METHODS OF USING RIFAXIMIN IN POSITION EMISSION TOMOGRAPHY (PET) SCANS
    Publication number: 20160128990
    Abstract: The present invention provides new methods and kits for the reduction, prevention or inhibition of substrate uptake by non-metastatic, metabolically active cells in a subject who will undergo a position emission tomography (PET) scan.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Inventor: Alan C. Moss
  • EXOSOMES AND MICROVESICLES IN INTESTINAL LUMINAL FLUIDS AND STOOL AND USE OF SAME FOR THE ASSESSMENT OF INFLAMMATORY BOWEL DISEASE
    Publication number: 20160122823
    Abstract: The present disclosure relates to methods of collecting intestinal luminal fluid (ILF) exosomes and microvesicles (EMV) and isolating corresponding mRNA in order to diagnose and treat inflammatory bowel diseases (IBD). In particular, certain embodiments relate to the method of capturing EMV from ILF applied to a filter device that is capable of capturing EMV. Nucleic acids such as mRNA can be isolated from the EMV using an oligo(dT)-coated plate designed to accommodate the filter device and then used for further molecular analysis. Quantification of the collected nucleic acids may then be used in the diagnosis and/or treatment of IBD.
    Type: Application
    Filed: November 3, 2015
    Publication date: May 5, 2016
    Inventors: Masato Mitsuhashi, Alan C. Moss