Patents by Inventor Alan Carpenter

Alan Carpenter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fibrin targeted therapeutics
    Publication number: 20070111947
    Abstract: Fibrin targeted therapeutic agents for the treatment of thromboembolism, infection, and cancer are provided.
    Type: Application
    Filed: October 16, 2006
    Publication date: May 17, 2007
    Inventors: Thomas McMurry, Andrew Kolodziej, Alan Carpenter, Simon Jones, Philip Graham, Richard Looby, Shrikumar Nair, Xifang Wang, Kirsten Overoye-Chan, John Barrett
  • PHARMACEUTICALS FOR THE IMAGING OF ANGIOGENIC DISORDERS
    Publication number: 20060003926
    Abstract: The present invention describes novel compounds of the formula: (Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.
    Type: Application
    Filed: July 18, 2003
    Publication date: January 5, 2006
    Inventors: Milind Rajopadhye, D. Edwards, John Barrett, Alan Carpenter, Thomas Harris, Stuart Heminway, Shuang Liu, Singh Prahlad
  • Matrix metalloproteinase inhibitors
    Publication number: 20050287074
    Abstract: Thus the present invention describes diagnostic agents comprising a diagnostic metal and a compound, wherein the compound comprises: 1-10 targeting moieties; a chelator; and 0-1 linking groups between the targeting moiety and chelator; wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to the diagnostic metal. The present invention also provides novel compositions of the compounds of the invention, kits, and their uses in diagnosis of diseases associated with MMPs.
    Type: Application
    Filed: August 1, 2005
    Publication date: December 29, 2005
    Applicant: Bristol-Myers Squibb Pharma Company
    Inventors: Alan Carpenter, Milind Rajopadhye
  • Matrix metalloproteinase inhibitors
    Publication number: 20050047999
    Abstract: Thus the present invention describes diagnostic agents comprising a diagnostic metal and a compound, wherein the compound comprises: 1-10 targeting moieties;a chelator; and 0-1 linking groups between the targeting moiety and chelator;wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to the diagnostic metal. The present invention also provides novel compositions of the compounds of the invention, kits, and their uses in diagnosis of diseases associated with MMPs.
    Type: Application
    Filed: August 21, 2003
    Publication date: March 3, 2005
    Inventors: Alan Carpenter, Milind Rajopadhye
  • MATRIX METALLOPROTEINASE INHIBITORS
    Publication number: 20050025702
    Abstract: Thus the present invention describes novel compounds comprising: 1-10 targeting moieties; a chelator (Ch); and 0-1 linking groups (Ln) between the targeting moiety and chelator; wherein the targeting moiety is a matrix metalloproteinase inhibitor; and wherein the chelator is capable of conjugating to a cytotoxic radioisotope. The present invention also provides novel compositions of the compounds of the invention, kits, and their uses in treatment of diseases associated with MMPs.
    Type: Application
    Filed: February 14, 2001
    Publication date: February 3, 2005
    Inventors: Carl Decicco, David Nelson, John Barrett, Alan Carpenter, Jingwu Duan, Milind Rajopadhye