Abstract: The present application relates to a variant Fc region comprising at least one modification relative to a wild-type human Fc region, where the modification selected from the group consisting of 434S, 252Y/428L, 252Y/434S, and 428L/434S, and the numbering is according to the EU index.

Abstract: Radionuclide brachytherapy sources and systems for applying beta radiation to a target area, for example for maintaining functioning drainage blebs or functioning drainage holes in the eye, e.g., to reduce intraocular pressure (IOP) of an eye being treated for glaucoma. The systems herein provide a substantially uniform dose across a particular area, thereby providing appropriate radiation therapies.

Abstract: Radionuclide brachytherapy sources and systems for applying beta radiation to a target area, for example for maintaining functioning drainage blebs or functioning drainage holes in the eye, e.g., to reduce intraocular pressure (IOP) of an eye being treated for glaucoma. The systems herein provide a substantially uniform dose across a particular area, thereby providing appropriate radiation therapies.

Abstract: An apparatus, and the method of using it, comprising one, or more, electronic sensors attached to a part(s) of a human or animal's body. The patient then performs an activity, or has an activity performed on them, and the results of the measured parameters are recorded by the sensor and processed, or downloaded and processed. The sensor may include a range of instrumentation, e.g. accelerometers, magnetometers, gyroscopes, force sensors, etc. to record positions (in the X, Y and Z planes), movements, angular movements, forces, stresses in bones/joints, etc. The use of the apparatus and method are appropriate to medical treatments, and perfecting sporting or dancing techniques and the results are processed to give the clinician or coach appropriate information to improve the problem being addressed. Methods for measuring lateral angular movement of hinged joints and spinal extension are taught.

Abstract: The invention discloses apparatus, and the method of using it, comprising one, or more, electronic sensors attached to a part(s) of a human or animal's body. The patient then performs an activity, or has an activity performed on them, and the results of the measured parameters are recorded by the sensor and processed, or downloaded and processed. The sensor may include a range of instrumentation, e.g. accelerometers, magnetometers, gyroscopes, force sensors, etc. to record positions (in the X, Y and Z planes), movements, angular movements, forces, stresses in bones/joints, etc. The use of the apparatus and method are appropriate to medical treatments, and perfecting sporting or dancing techniques and the results are processed to give the clinician or coach appropriate information to improve the problem being addressed. Methods for measuring lateral angular movement of hinged joints and spinal extension are taught.