Abstract: A method of operating a memory device that includes the steps of receiving a read command and a target address in a non-volatile memory (NVM) array, in which the NVM array is divided into a plurality of blocks based on row and column addresses, performing a read operation on NVM cells in the target address and coupling an output of each NVM cell read to a sensing circuit, generating a local reference voltage based on a base reference voltage and an adjustment reference voltage corresponding to the target address of the NVM cells being read and a block that the NVM cells belong thereto, and offsetting the base reference voltage with the adjustment reference voltage, and coupling the local reference voltage to the sensing circuit. Other embodiments are also described.

Abstract: Disclosed herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and their pharmaceutical compositions: The compounds are useful as agonists of Stimulator of Interferon Genes (STING), such as in a method of treating a tumor.

Abstract: The present disclosure provides compounds having Stimulator of Interferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors in patients afflicted therewith. The compounds are a compound of formula (I) or formula (II): wherein the substituents are as defined herein. Ring A is a bicyclic fully aromatic or partially reduced heteroaryl ring system comprising 3, 4, or 5 N atoms, substituted with 0, 1, 2, 3,or 4 substituents as defined herein. Compounds for practice of a method of the present disclosure can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immune-checkpoint targeting drug.

Abstract: The invention provides compounds having STimulator of INterferon Genes (STING) agonistic bioactivity that can be used in the treatment of tumors inpatients afflicted therewith. The compounds are of formula (IA), formula (I), and formula (II): wherein the various substituents are as defined herein. Ring A is a 5- or 6-membered heteroaryl comprising 1, 2, or 3 N atoms, unsubstituted or substituted with 1, 2, or 3 groups as defined herein. Compounds for practice of a method of the invention can be delivered via oral delivery for systemic exposure, as well as delivered intratumorally. Antitumor therapy using a compound of formula (I) can further comprise administration of an effective dose of an immunecheckpoint targeting drug.

Abstract: Method and apparatus for managing versions of a portion of a document on a computing system are described. Multiple versions of an object in the document are maintained on the computing system. A graphical representation of at least two versions of the object is displayed on a display to a user of the computing system. A previous version of the object is selected from the at least two versions of the object through an input device, and the object in the document is restored to the selected previous version. The object is a portion of the document less than the entirety of the document.

Abstract: Method and apparatus for managing versions of a portion of a document on a computing system are described. Multiple versions of an object in the document are maintained on the computing system. A graphical representation of at least two versions of the object is displayed on a display to a user of the computing system. A previous version of the object is selected from the at least two versions of the object through an input device, and the object in the document is restored to the selected previous version. The object is a portion of the document less than the entirety of the document.

Abstract: Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation.

Abstract: Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation.

Abstract: Method and apparatus for color management of documents retrieved and manipulated by a server based application and displayed on a client device through a browser application. Page elements of documents are manipulated to provide consistent and/or accurate color reproduction on the client device. Pages include untagged images, images tagged with color profiles, and tagged or untagged page elements specified by hex color values. Color values for images and untagged page elements specified by hex color values are adjusted by the server application before transmission to the client device to account for properties of browser applications and operating systems of different client devices.

Abstract: Method and apparatus for managing versions of a portion of a document on a computing system are described. Multiple versions of an object in the document are maintained on the computing system. A graphical representation of at least two versions of the object is displayed on a display to a user of the computing system. A previous version of the object is selected from the at least two versions of the object through an input device, and the object in the document is restored to the selected previous version. The object is a portion of the document less than the entirety of the document.

Abstract: Method and apparatus for color management of documents retrieved and manipulated by a server based application and displayed on a client device through a browser application. Page elements of documents are manipulated to provide consistent and/or accurate color reproduction on the client device. Pages include untagged images, images tagged with color profiles, and tagged or untagged page elements specified by hex color values. Color values for images and untagged page elements specified by hex color values are adjusted by the server application before transmission to the client device to account for properties of browser applications and operating systems of different client devices.

Abstract: Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation.

Abstract: Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation.

Abstract: Various features and processes related to document collaboration are disclosed. In some implementations, animations are presented when updating a local document display to reflect changes made to the document at a remote device. In some implementations, a user can selectively highlight changes made by collaborators in a document. In some implementations, a user can select an identifier associated with another user to display a portion of a document that includes the other user's cursor location. In some implementations, text in document chat sessions can be automatically converted into hyperlinks which, when selected, cause a document editor to perform an operation.

Abstract: The invention includes pieces of ceramic armor, methods of joining a carbide with a metal-comprising piece, and methods of metallizing carbide-comprising surfaces. In one implementation, a method of joining a carbide with a metal-comprising piece includes providing a mixture comprising (a) and (b) over a carbide-comprising surface of a substrate, where (a) comprises at least one of niobium and titanium, and (b) comprises silicon. The mixture is heated over the carbide-comprising surface at least to the melting temperatures (a) and (b). The melted mixture is solidified into an adherent layer on the substrate. A metal-based joining material is provided over the adherent layer. Metal of a metal-comprising piece is welded to the substrate with the metal-based joining material.

Abstract: A system and method for managing persistent objects with a persistent object framework is disclosed. The persistent object framework receives queries and instructions from an application for data from the persistent objects. The persistent objects are stored in data sources, such as databases or repositories. The persistent object framework may create, save, update, access, search, and delete persistent objects. Further, the persistent object framework caches applicable persistent objects for the application. The persistent object framework provides the caching for the persistent objects. The persistent object framework supports both Lightweight Directory Access Protocol and relational databases.

Abstract: A system and method for managing persistent objects with a persistent object framework is disclosed. The persistent object framework receives queries and instructions from an application for data from the persistent objects. The persistent objects are stored in data sources, such as databases or repositories. The persistent object framework may create, save, update, access, search, and delete persistent objects. Further, the persistent object framework caches applicable persistent objects for the application. The persistent object framework provides the caching for the persistent objects. The persistent object framework supports both Lightweight Directory Access Protocol and relational databases.