Abstract: A cryo-ablation system treats conditions associated with sympathetic nervous system hyperactivity using a catheter with a configurable heat transfer element that transitions from a flat delivery profile to deployed configurations including helical shapes. The system includes deployable temperature probes that directly measure tissue temperature at target locations inside or outside blood vessels. A computational control system processes temperature data from multiple sensors and deployable probes to calculate real-time lethal isotherm progression using heat transfer modeling algorithms. The system provides vessel occlusion during treatment and real-time feedback for treatment optimization.

Abstract: A lid for a beverage can in which the lid is designed to facilitate its use, such as, for example, by being openable intuitively, with a single hand, and through spring-loading. Also, the beverage can, including the lid, may be manufactured more efficiently.