Abstract: A method and system for health and lifestyle interventions is provided, the system comprising three modules: an evaluation module, a suggestion module and a user interface module. The evaluation module uses rigorous statistical comparison of the levels before and after the start of the intervention and the suggestion module guides the individual through the process by the user interface module.

Abstract: Compositions and formulations comprising peptide conjugate compounds are provided, including native and modified variants of chlorotoxin peptide conjugated to detectable agents or active agents. Methods of detecting and treating vascular lesions, vascular malformations, and vascular abnormalities including cerebral cavernous malformation (CCM) with peptide conjugate compounds are also provided, including methods of imaging and resecting vascular lesions tissues and cells.

Abstract: A packaging arrangement for 30 mm×173 mm ammunition rounds. The packaging arrangement has a heavy duty standoff device of defined height, which standoff device mounts a very high strength support plate and a heavy duty restraining plate. The support plate has through holes (of diameter slightly less than the rounds defined maximum diameter) to hold the rounds of in an upside down position and from sliding/moving. The height of the standoff device keeps the rounds from being able to touch the bottom of the metal box. The restraining plate has multiple recessed areas sized to accommodate the back ends of the said rounds. The packaging arrangement is lowered into a metal box with handles for carriage purposes. On top, there are Homosite filler pads, and the box accommodates a top lid.

Abstract: An embodiment in accordance with the present invention provides a transducer design for minimally invasive focused ultrasound (MIFU). The present invention allows flexible control of a focused ultrasound wave using mechanical and electrical control. The transducer array is implemented on a flexible substrate that can be mechanically controlled through two or more physical configurations. As with conventional electronic “steering,” the transducer elements can be controlled electronically to provide adjustable focus of the ultrasound. The combination of mechanical and electronic control provides the device a very flexible method for delivering focused ultrasound. The invention also includes a design that allows integration of ultrasound and endoscopic image guidance. The ultrasound guidance includes anatomical visualization and functional imaging (e.g. blood flow and coagulation of vasculature). The ultrasound imaging transducer is used for thermometry within the region of interest for treatment.

Abstract: The disclosure relates to methods of preserving or improving microvascular integrity in a patient in need thereof comprising administering pirfenidone therapy to the patient.

Abstract: Devices and methods to assist a user in donning hosiery are provided. The device comprises an elongated flexible blade extending between a distal end and a proximal end, the blade configured to contact at least a portion of a user's foot, the blade having a textured inner surface configured to face towards the user's lower leg, and an smooth opposing outer surface relative to the textured inner surface.

Abstract: The disclosure relates to methods of preserving or improving microvascular integrity in a patient in need thereof comprising administering pirfenidone therapy to the patient.

Abstract: Devices and methods to assist a user in donning hosiery are provided. The device comprises an elongated flexible blade extending between a distal end and a proximal end, the blade configured to contact at least a portion of a user's foot, the blade having a textured inner surface configured to face towards the user's lower leg, and an smooth opposing outer surface relative to the textured inner surface.

Abstract: A cage for small animals includes a generally closed base having an open top; a grating structure upon the base forming a closed structure for containing an animal therein; and a refuse catcher surrounding the grating structure and removably fastened to the base so as to permit the refuse catcher to be removed from the base by being detached from the base and moved upward away from the base without removing the grating structure from the base. The cage can be a bird cage, wherein the refuse catcher is a seed catcher that is formed of a plurality of mating parts, the parts being releasable attached to each other and to the base.

Abstract: An improvement for an assembly for use in a computing device which includes a microprocessor and a motherboard and a socket for receiving and making electric contact with the microprocessor. A heat sink is included which is in thermal contact with the microprocessor whereby a water barrier is applied to and proximate the socket for preventing water of condensation from contacting areas covered by the water barrier and a moisture absorbent surrounding the heat sink.

Abstract: Computing devices, including laptop computers, desk top computers, servers and video game terminals employ microprocessors which generate considerable heat. In fact, the heat generated from microprocessors is generally considered the limiting factor in computing speed. A heat sink is provided in thermal contact with a microprocessor whereby a water barrier is applied to and proximate a socket configured within the computing device's motherboard for preventing water of condensation from contacting areas covered by the water barrier.

Abstract: Computing devices, including laptop computers, desk top computers, servers and video game terminals employ microprocessors which generate considerable heat. In fact, the heat generated from microprocessors is generally considered the limiting factor in computing speed. A heat sink is provided in thermal contact with a microprocessor whereby a water barrier is applied to and proximate a socket configured within the computing device's motherboard for preventing water of condensation from contacting areas covered by the water barrier.

Abstract: An exercise machine is particularly adapted for use by handicapped persons or other physically limited persons. The exercise machine includes a plurality of exercise mechanisms operable from a single station so that the handicapped person does not have to move between different stations. The plurality of exercise mechanisms are operatively connected to a single brake mechanism to that each exercise mechanism can be independently manipulated. One of the exercise mechanisms includes an overhead bar assembly which is operable as a bench press or as an overhead press.