Abstract: A tube seal configured to fluidically seal and connect a first and second tube includes an elastomeric seal conduit having a conduit skeleton. The elastomeric seal conduit extends along a longitudinal axis having a first end opposite a second end and having a hollow portion configured to transport a fluid between the first and second tubes. The conduit skeleton may be temporarily or permanently connected to the elastomeric seal conduit and extends along the longitudinal axis generally between the first and second ends. The conduit skeleton has a first band disposed a distance from a second band where the bands are aligned about the longitudinal axis and where at least one rib extends between and connects the bands. The conduit skeleton may be made from a different material in comparison to the elastomeric seal conduit or may have a higher modulus of elasticity in comparison to the elastomeric seal conduit.