Patents by Inventor Alan Cullen

Alan Cullen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
    Patent number: 9089484
    Abstract: The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in an object after oral administration comprising orally administering a pharmaceutical composition as described above.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: July 28, 2015
    Assignee: Merrion Research III Limited
    Inventors: Thomas W. Leonard, David C. Coughlan, Alan Cullen
  • Pharmaceutical compositions of iron for oral administration
    Patent number: 8802114
    Abstract: The present invention generally relates to orally administered pharmaceutical compositions of iron compounds with medium chain fatty acid salts. The invention further relates to methods of using the pharmaceutical compositions to treat iron deficiency and related disorders.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: August 12, 2014
    Assignee: Merrion Research III Limited
    Inventors: Alan Cullen, Edel O'Toole, David C. Coughlan, Kishore Chalasani, Thomas W. Leonard
  • Pharmaceutical Compositions of Iron for Oral Administration
    Publication number: 20120189692
    Abstract: The present invention generally relates to orally administered pharmaceutical compositions of iron compounds with medium chain fatty acid salts. The invention further relates to methods of using the pharmaceutical compositions to treat iron deficiency and related disorders.
    Type: Application
    Filed: January 6, 2012
    Publication date: July 26, 2012
    Inventors: Alan Cullen, Edel O'Toole, David C. Coughlan, Kishore Chalasani, Thomas W. Leonard
  • Pharmaceutical Compositions of Selective Factor Xa Inhibitors for Oral Administration
    Publication number: 20120156294
    Abstract: The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable salt thereof and an enhancer, wherein the enhancer is a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from 4 to 20 carbon atoms. The present invention also provides a method for obtaining a reproducible bioavailability of selective factor Xa inhibitor in a subject after oral administration comprising orally administering a pharmaceutical composition as described above.
    Type: Application
    Filed: September 23, 2011
    Publication date: June 21, 2012
    Inventors: Thomas W. Leonard, David C. Coughlan, Alan Cullen
  • Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
    Publication number: 20110182985
    Abstract: The present invention provides pharmaceutical compositions which are effective in providing therapeutically effective blood levels of a therapeutically active ingredient to a subject when administered to a gastrointestinal tract. In one aspect, the pharmaceutical compositions comprise a therapeutically effective amount of a therapeutically active ingredient; at least one water soluble enhancer, e.g., a medium chain fatty acid or a salt, ester, ether, or derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms; and a saccharide.
    Type: Application
    Filed: January 26, 2011
    Publication date: July 28, 2011
    Inventors: David C. Coughlan, Thomas W. Leonard, Bozena Adamczyk, Kieran Madigan, Edel O'Toole, Alan Cullen, Jason O'Hara