Patents by Inventor Alan D. Kinghorn

Alan D. Kinghorn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low cariogenic sweetening agents
    Patent number: 4808409
    Abstract: Racemic hernandulcin, a sesquiterpene, possesses a sweetness intensity about three orders of magnitude greater than that of sucrose. It is non-mutagenic and non-toxic under conventional assay procedures. In addition to attractive utility in foods, beverages and pharmaceutical compositions, it affords a low-cariogenic, essentially non-nutritive sweetening agent for inclusion in oral hygiene products.
    Type: Grant
    Filed: August 16, 1984
    Date of Patent: February 28, 1989
    Assignee: Board of Trustees, University of Illinois
    Inventors: Alan D. Kinghorn, Cesar M. Compadre, John M. Pezzuto
  • Purification of 12-O-tetradecanoylphorbol-13-acetate, phorbol, and 4.alpha. -
    Patent number: 4468328
    Abstract: Droplet counter-current chromatography is utilized to isolate and purify 12-O-tetradecanoylphorbol-13-acetate (TPA), phorbol, and the diastereoisomer 4.alpha.-phorbol from croton oil. The stationary and mobile phases for the procedure are derived from an equilibrated mixture of hexane-diethylether-n-propanol-ethanol-water, the separated upper layer of which comprises the stationary phase and the bottom layer of which the mobile phase. The TPA and the phorbol isomers are obtained in exceptionally high purity by further treatment with liquid column chromatography and thin-layer chromatography.
    Type: Grant
    Filed: January 17, 1983
    Date of Patent: August 28, 1984
    Assignee: The Board of Trustees of the University of Ill.
    Inventors: Alan D. Kinghorn, Gary T. Marshall