Patents by Inventor Alan D. Watson
Alan D. Watson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240075352Abstract: A golf club head with a sole having a low stiffness compliance zone, which allows the face to deflect downward upon impact with a golf ball, is disclosed herein. The compliance zone comprises a plurality of through openings that are filled with one or more filler pieces comprising a low modulus material, all of which are located within three inches of a face section measured along a front-to-back axis of the golf club head.Type: ApplicationFiled: November 10, 2023Publication date: March 7, 2024Applicant: Topgolf Callaway Brands Corp.Inventors: Irina Ivanova, Brandon D. DeMille, Alan Hocknell, William C. Watson, Timothy G. Scott, Romulus M. Tomimbang, Justin Del Rosario
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Publication number: 20220160947Abstract: Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.Type: ApplicationFiled: February 11, 2022Publication date: May 26, 2022Inventors: Anthony DePasqua, Kevin Eggan, JR., Kevin Kalish, Manual A. Navia, Kasper Roet, Ching-Hua Tseng, Alan D. Watson, William X. Siopes, Gianna N. Riccardi, Marcie Ann Glicksman
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Patent number: 11278657Abstract: Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.Type: GrantFiled: October 2, 2020Date of Patent: March 22, 2022Assignee: EnClear Therapies, Inc.Inventors: Anthony DePasqua, Kevin Eggan, Jr., Kevin Kalish, Manuel A. Navia, Kasper Roet, Ching-Hua Tseng, Alan D. Watson, William X. Siopes, Gianna N. Riccardi, Marcie Ann Glicksman
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Publication number: 20210023293Abstract: Cerebrospinal fluid (CSF) and other fluid amelioration systems completely or partially implantable within a mammalian subject and associated methods include a substrate and an agent for amelioration of a toxic biomolecule present in the CSF or fluid, wherein the agent is disposed on or within the substrate.Type: ApplicationFiled: October 2, 2020Publication date: January 28, 2021Inventors: Anthony DePasqua, Kevin Eggan, JR., Kevin Kalish, Manuel A. Navia, Kasper Roet, Ching-Hua Tseng, Alan D. Watson, William X. Siopes, Gianna N. Riccardi, Marcie Ann Glicksman
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Publication number: 20090011977Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: ApplicationFiled: June 27, 2008Publication date: January 8, 2009Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Publication number: 20080287347Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: ApplicationFiled: June 27, 2008Publication date: November 20, 2008Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Patent number: 7408025Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: GrantFiled: December 15, 2000Date of Patent: August 5, 2008Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Patent number: 7335725Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: GrantFiled: May 4, 2005Date of Patent: February 26, 2008Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Patent number: 6911525Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: GrantFiled: December 15, 2000Date of Patent: June 28, 2005Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Patent number: 6794490Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: GrantFiled: December 15, 2000Date of Patent: September 21, 2004Assignee: Cubist Pharmaceuticals, Inc.Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xian Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Publication number: 20040067878Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: ApplicationFiled: December 15, 2000Publication date: April 8, 2004Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Publication number: 20030082597Abstract: Disclosed is a method of identifying an biological age-associated marker. The method can include: providing a first organism having a first genotype and a second organism having a second genotype, wherein the first and second organisms are derived from the same species and are the same chronological age; and comparing a property associated with a biomolecule in the first organism to a property associated with the biomolecule in the second organism to identify a biomolecule having a preselected value for said property, thereby identifying the biomolecule as an biological age-associated marker.Type: ApplicationFiled: August 15, 2002Publication date: May 1, 2003Inventors: L. Edward Cannon, Cynthia A. Bayley, Cynthia J. Kenyon, Leonard P. Guarente, Alan D. Watson
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Publication number: 20020058785Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: ApplicationFiled: December 15, 2000Publication date: May 16, 2002Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Publication number: 20020025924Abstract: The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.Type: ApplicationFiled: December 15, 2000Publication date: February 28, 2002Inventors: Jason Hill, Ian Parr, Michael Morytko, Jim Siedlecki, Xiang Yang Yu, Jared Silverman, Dennis Keith, John Finn, Dale Christensen, Tsvetelina Lazarova, Alan D. Watson, Yan Zhang
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Patent number: 5972307Abstract: This invention relates to dichelants, in particular compounds having two macrocyclic chelant groups linked by a bridge containing an ester or amide bond, especially compounds of formula Vb ##STR1## (wherein each X which may be the same or different is NZ, O or S, at least two Xs being NZ;each Z is a group R.sup.1 or a group CR.sup.1.sub.2 Y, at least one Z, and preferably 2 or 3 Zs, on each macrocyclic ring being a group CR.sup.1.sub.2 Y;each Y is a group CO.sub.2 H, PO.sub.3 H, SO.sub.3 H, CONR.sup.1.sub.2, CON(OR.sup.1)R.sup.1, CNS or CONR.sup.1 NR.sup.1.sub.2, preferably COOH;m is 0 or 1 or 2, preferably 1; each n is 2 or 3, preferably 2; q is 1 or 2, preferably 1;each R.sup.Type: GrantFiled: July 22, 1997Date of Patent: October 26, 1999Assignee: Nycomed Salutar, Inc.Inventors: Joan Carvalho, Alan D. Watson, Jere D. Fellmann, Michael Koo
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Patent number: 5932190Abstract: An x-ray contrast medium containing a multinuclear complex of the formula (M.sub.6 (.mu..sub.3 B).sub.8 A.sub.v).sub.x L.sub.w, wherein M is Mo, W, Re Tc, V, Nb, Ta, Ru, or Fe; .mu..sub.3 B represent a tridentate bridging atom; A is a non-bridging atom; L is a ligand coordinately bonded to at least one M atom; x is a positive integer; and v and w are independently zero or positive integers.Type: GrantFiled: June 7, 1995Date of Patent: August 3, 1999Assignee: Nycomed Salutar, Inc.Inventors: Torsten Almen, Arne Berg, Michael Droege, Harald Dugstad, Jere D. Fellman, Sook-Hui Kim, Jo Klaveness, Scott M. Rocklage, Pal Rongved, Brent Segal, Alan D. Watson
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Patent number: 5914095Abstract: There are provided polychelants and their metal chelates which are useful in diagnostic imaging and in radiotherapy and which comprise a plurality of macrocyclic chelant moieties, e.g. DOTA residues, conjugated to a dendritic polyamine backbone molecule, e.g. a starburst dendrimer. To produce a site-specific polychelate, one or more of the macrocyclic chelant carrying backbone molecules may be conjugated to a site-directed macromolecule, e.g. a protein.Type: GrantFiled: October 7, 1991Date of Patent: June 22, 1999Assignee: Salutar, Inc.Inventor: Alan D Watson
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Patent number: 5688486Abstract: Compounds including tight molecular meshes, preferably curved in one or two directions, such as fullerenes and met-cars, can be used as carriers for diagnostic or therapeutic agents, especially diagnostic contrast agents.Type: GrantFiled: October 31, 1994Date of Patent: November 18, 1997Assignee: Nycomed Salutar, Inc.Inventors: Alan D. Watson, Jo Klaveness, Gene C. Jamieson, Jere D. Fellmann, Nils B. Vogt
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Patent number: 5679810Abstract: Linear oligomer polychelant compounds and chelates formed therewith have alternating chelant and linker moieties bound together by amide or ester moieties. The compounds have between 3 and 100 chelant moieties, at least one of which complexes a paramagnetic metal ion. The polychelants and especially their paramagnetic metal polychelates are particularly suitable for diagnostic imaging.Type: GrantFiled: June 7, 1995Date of Patent: October 21, 1997Assignee: Salutar, Inc.Inventors: David B. Love, William C. Dow, Richard J. Himmelsbach, Alan D. Watson, Scott M. Rocklage
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Patent number: 5650133Abstract: This invention relates to dichelants, in particular compounds having two macrocyclic chelant groups linked by a bridge containing an ester or amide bond, especially compounds of formula Vb ##STR1## (wherein each X which may be the same or different is NZ, O or S, at least two Xs being NZ;each Z is a group R.sup.1 or a group CR.sup.1.sub.2 Y, at least one Z, and preferably 2 or 3 Zs, on each macrocyclic ring being a group CR.sup.1.sub.2 Y;each Y is a group CO.sub.2 H, PO.sub.3 H, SO.sub.3 H, CONR.sup.1.sub.2, CON(OR.sup.1)R.sup.1, CNS or CONR.sup.1 NR.sup.1.sub.2, preferably COOH;m is 0 or 1 or 2, preferably 1; each n is 2 or 3, preferably 2; q is 1 or 2, preferably 1;each R.sup.Type: GrantFiled: April 12, 1994Date of Patent: July 22, 1997Assignee: Nycomed SalutarInventors: Joan Carvalho, Alan D. Watson, Jere D. Fellmann, Michael David Koo