Abstract: The invention provides an apparatus for the generation and administration of a micro-nanobubble solution to a tissue, a method for the treatment of a tissue with a solution of micro-nanobubbles, and a kit for the treatment of tissue with micro-nanobubbles.

Abstract: A skin adherent device is presented. The skin adherent device includes a first portion configured for attaching to a first portion of an anatomy. A second portion is configured for attaching to a second portion of the anatomy. A tubular bridge portion is configured for attaching to a third portion of the anatomy. The first portion and the second portion comprise a tacky gel material. The first portion and the second portion form a nasal dilator that prevents an outer wall tissue of nasal passages from drawing in during breathing.

Abstract: A skin adherent device is presented. The skin adherent device includes a first portion configured for attaching to a first portion of an anatomy. A second portion is configured for attaching to a second portion of the anatomy. A third portion is configured for attaching to a third portion of the anatomy. The second portion and the third portion are disposed on opposing ends of the skin adherent device. The first portion, the second portion and the third portion include a tacky gel material.

Abstract: A wound closure device has internal and external components designed to close, shrink or approximate an open wound. The internal component preferably comprises sachets filled with highly absorbent material such as carboxymethylcellulose, disposed at the surface of the wound bed to absorb exudate from the wound. The external components preferable include paddles that adhere to the skin, and form part of, or have a mechanism to couple to an elastic tensioning fabric. The internal component is placed between the open wound and the elastic tensioning fabric, such that expansion of the internal component applies pressure on the wound base. It is contemplated that the two components will work synergistically together to create ‘micro-deformation’ forces that stimulate granulation tissue.

Abstract: Postoperative scars are treated by a method of applying a microporous paper tape to the scar running along the length of the scar. A contact medium is applied to the exposed surface of the tape and penetrates to the skin. The contact medium comprises an expressed gel from the plant Bulbine frutescens and may contain asiaticoside and panthenol. These active ingedients are contained in a pharmaceutically acceptable cream. The contact material is applied each morning and evening. The tape is replaced when it falls away from the skin normally, e.g. every seven days and the treatment is then continued. Improved scar healing results from the use of this method.