Patents by Inventor Alan Daugherty

Alan Daugherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT FOR AORTOPATHY
    Publication number: 20240139229
    Abstract: A method of treating an aortopathy is disclosed, including identifying a subject having or at risk of developing the aortopathy and reducing the expression of and/or activity of gasdermin D (GSDMD) in the subject. The method may include administering to the subject an effective amount of a GSDMD inhibitor. The GSDMD inhibitor may reduce the expression of GSDMD in the subject and/or may reduce the activity of GSDMD in the subject.
    Type: Application
    Filed: June 22, 2022
    Publication date: May 2, 2024
    Inventors: Congqing Wu, Hong S. Lu, Alan Daugherty, Zhenyu Li, Hua Li
  • Inhibiting angiotensinogen to attenuate aortic pathology in Marfan syndrome
    Patent number: 11649458
    Abstract: Disclosed herein is a method for attenuating aortic pathology in a subject having Marfan syndrome by reducing angiotensinogen plasma levels in the subject.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: May 16, 2023
    Assignee: University of Kentucky Research Foundation
    Inventors: Alan Daugherty, Hong Lu, Mary Sheppard, Jeff Chen
  • INHIBITING ANGIOTENSINOGEN TO ATTENUATE AORTIC PATHOLOGY IN MARFAN SYNDROME
    Publication number: 20210348168
    Abstract: Disclosed herein is a method for attenuating aortic pathology in a subject having Marfan syndrome by reducing angiotensinogen plasma levels in the subject.
    Type: Application
    Filed: May 5, 2021
    Publication date: November 11, 2021
    Inventors: Alan Daugherty, Hong Lu, Mary Sheppard, Jeff Chen