Patents by Inventor Alan E. Blize

Alan E. Blize has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triamide-substituted heterobicyclic compounds
    Patent number: 7482368
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
    Type: Grant
    Filed: August 2, 2005
    Date of Patent: January 27, 2009
    Assignee: Pfizer Inc
    Inventors: Peter Bertinato, Brian Bronk, Alan E. Blize, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Patent number: 7348355
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: March 25, 2008
    Assignee: Pfizer Inc.
    Inventors: Peter Bertinato, Alan E. Blize, Brian Bronk, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Patent number: 6979692
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: December 27, 2005
    Assignee: Pfizer Inc.
    Inventors: Peter Bertinato, Alan E. Blize, Brian S. Bronk, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Patent number: 6949572
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: September 27, 2005
    Assignee: Pfizer Inc.
    Inventors: Peter Bertinato, Brian S. Bronk, Alan E. Blize, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Publication number: 20040087625
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 1
    Type: Application
    Filed: August 13, 2003
    Publication date: May 6, 2004
    Applicant: Pfizer Inc
    Inventors: Peter Bertinato, Brian S. Bronk, Alan E. Blize, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Patent number: 6720351
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 wherein R1-R8 are as defined in the specification, as well as pharmaceutical compositions and uses thereof, and processes for preparing the compounds. The compounds of the invention are useful for the treatment of obesity and lipid disorders.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: April 13, 2004
    Assignee: Pfizer Inc.
    Inventors: Peter Bertinato, Alan E. Blize, Brian S. Bronk, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • Triamide-substituted heterobicyclic compounds
    Publication number: 20030187053
    Abstract: The invention relates to triamide MTP/ApoB inhibitors of the formula 1 1
    Type: Application
    Filed: June 20, 2002
    Publication date: October 2, 2003
    Applicant: Pfizer Inc.
    Inventors: Peter Bertinato, Alan E. Blize, Brian S. Bronk, Hengmiao Cheng, Jin Li, Hiep Huatan, Clive Mason
  • 13-membered azalides and their use as antibiotic agents
    Patent number: 6329345
    Abstract: The invention relates to a method of preparing compounds of the formula 1 and to pharmaceutically acceptable salts thereof. The compounds of formula 1 are antibacterial agents that may be used to treat various bacterial and protozoa infections. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of treating bacterial protozoa infections by administering the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1 and to intermediates useful in such preparation.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: December 11, 2001
    Assignee: Pfizer Inc
    Inventors: Robert J. Rafka, Barry J. Morton, Colman B. Ragan, Peter Bertinato, John P. Dirlam, Alan E. Blize, Carl B. Ziegler