Abstract: A system for serially injecting liquids includes a syringe body defining a syringe proximal opening and a distal needle interface, proximal and distal stopper members, forming proximal and distal chambers. The system also includes a first liquid in the distal chamber and a second liquid in the proximal chamber, and a plunger configured to be manually manipulated to insert the proximal stopper member distally. Moreover, the system includes a needle hub assembly coupled to the syringe body, the needle assembly including a needle. The needle defines a needle interior, and distal, middle and proximal openings. The distal, middle and proximal openings are fluidly coupled through the needle interior. Manipulating the plunger member to insert the proximal stopper member initially expels the first liquid from the distal chamber, then serially expels the second liquid from the proximal chamber.

Abstract: In one embodiment, a system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a stopper member disposed in the syringe interior. Moreover, the system includes a plunger member coupled to the stopper member. In addition, the system includes a finger flange removably coupled to the syringe flange, the finger flange including a proximally directed screw. The system also includes a rotatable member disposed on the proximally directed screw, the rotatable member defining a rotatable member opening through which the plunger member is disposed and having an elastic latch disposed adjacent the rotatable member opening.

Abstract: A system for injecting includes a syringe body, a syringe interior, a syringe flange, and a stopper member and an injectable fluid disposed in the syringe interior. The system also includes a plunger member coupled to the stopper member. The system further includes a finger flange removably coupled to the syringe flange, the finger flange defining a pair of side openings and a pair of bumps adjacent respective side openings. Moreover, the system also includes a swing spacer rotatably coupled to the finger flange, the swing spacer defining a pair of arms, a pair of pivot pins, two pairs of slots, and a pair of indentations. The swing spacer is configured to define a distance of movement of the plunger member relative to the syringe body along a longitudinal axis of the syringe body, thereby defining a dose of the injectable fluid.

Abstract: A system for injection includes a disposable portion and a reusable portion. The disposable portion includes a syringe body having proximal and distal ends, a syringe interior, and a disposable portion flange at the proximal end thereof, an injectable fluid disposed in the syringe interior, a stopper member disposed in the syringe interior, and a plunger member coupled to the stopper member, wherein the plunger member defines a rack gear including a plurality of rack gear teeth. The reusable portion is configured to be removably coupled to the disposable portion. The reusable portion includes a gear assembly including a pinion gear configured to sequentially advance the plunger member distally by a predetermined distance, and a finger flange coupled to the disposable portion flange.

Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.

Abstract: An injection system includes an injection system body, a proximal stopper member, and a distal stopper member, wherein the proximal stopper member, the distal stopper member, and the injection system body form proximal and distal drug chambers. The system further includes a plunger member configured to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a needle hub assembly coupled to the syringe body at the syringe body distal end, and including a needle hub and a needle. The distal stopper member includes a ball having a lodged state and a dislodged state. When the ball is in the lodged state, the ball forms an openable barrier between the proximal and distal drug chambers. The distal stopper member is configured to selectively allow flow from the proximal drug chamber to the distal drug chamber.

Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes an injectable fluid disposed in the syringe interior. The system further includes a finger flange coupled to the syringe flange. Moreover, the system includes a stopper member disposed in the syringe interior. In addition, the system includes a plunger ratchet member coupled to the stopper member. The system also includes a plunger tube disposed coaxially around at least a portion of the plunger ratchet member and operatively coupled thereto.

Abstract: A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is at least partially retractable into plunger interior. The needle proximal end feature includes an annular distally facing surface.

Abstract: A system for injection includes a syringe body having proximal and distal ends, and defining a syringe body interior therebetween. The system also includes a needle hub assembly coupled to the syringe body distal end. The needle hub assembly includes a needle hub, and a needle removably coupled thereto and having a sharp needle distal end and a needle proximal end feature. The system further includes a stopper member movably disposed in the syringe interior. Moreover, the system includes a plunger member having proximal and distal ends, and coupled to the stopper member at the distal end. The plunger member is configured to insert the stopper member distally in the syringe interior. When the stopper member is inserted to the syringe body distal end, the plunger member proximal end is flush with the syringe body proximal end or disposed in the syringe body interior.

Abstract: One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

Abstract: A system for safe injections includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a needle hub assembly coupled to the distal end of the syringe body. The needle hub assembly includes a needle hub coupled to the distal end of the syringe body, and a needle removably coupled to the needle hub. The system further includes a stopper member disposed in the syringe interior. Moreover, the system includes a plunger member coupled to the stopper member. The plunger member includes a plunger housing defining a plunger interior, a spring and a latch, and a needle catch and a trigger. The spring and the latch are integrally formed, and the needle catch and the trigger are integrally formed.

Abstract: A system for injection includes a syringe body having proximal and distal ends and defining a syringe interior, a stopper member disposed in the syringe interior, a needle hub assembly coupled to the syringe body at the distal end thereof, and a plunger member coupled to the stopper member and configured to be manipulated to insert the stopper member distally in the syringe interior relative to the syringe body and the needle hub. The plunger member includes a plunger body defining a plunger interior, a retraction member disposed in the plunger interior, and a spring disposed in the plunger interior. The retraction member includes a catch-latch and a trigger movably disposed in the catch-latch along a longitudinal axis thereof. The trigger defines a proximal radial extension, a distal radial extension, and an annular trough between the proximal and distal radial extensions.

Abstract: A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

Abstract: A system for injecting includes a cartridge body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the cartridge body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the cartridge body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

Abstract: A polyaxial bone anchor including a housing, a bone screw, and a retainer for pivotably coupling the head of the bone screw to the housing. The retainer is positioned into the bore of the housing and includes a plurality of alternating tabs and slots circumferentially arranged to define a cavity for receiving the head portion of the bone screw therein. The retainer is axially moveable in the housing from a first position in which the head portion is not passable through the lower opening of the retainer to a second position in which the head position is passable through the lower opening of the retainer.

Abstract: An injection system includes a molded body member having a body connection member at a distal end of the molded body member. The system also includes a needle hub assembly coupled to the distal end of the molded body member. The needle hub assembly includes a needle hub coupled to the body connection member of the molded body member, a needle coupled to the needle hub, and a barbed band disposed around a proximal end of the needle hub and having a barb. The barbed band allows rotation of the needle hub assembly relative to the body connection member in a first direction, while preventing rotation of the needle hub assembly relative to the body connection member in a second direction.

Abstract: One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

Abstract: A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is at least partially retractable into plunger interior. The needle proximal end feature includes an annular distally facing surface.

Abstract: A system for injecting includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member. The plunger member includes a rotatable member configured to insert the stopper member distally in the syringe interior relative to the syringe body with rotation of the rotatable member. The plunger member further includes a proximal portion proximal of the rotatable member configured to be moved distally to also insert the stopper member distally in the syringe interior relative to the syringe body to eject about microliters of fluid from the syringe interior.

Abstract: A system for medication dispensing includes a syringe body having proximal and distal ends, a syringe interior, a syringe flange at the proximal end thereof, and a drug disposed in the syringe interior. The system also includes a finger flange coupled to the syringe flange and defining a finger flange interior and a side window therethrough. The system further includes a stopper member disposed in the syringe interior. Moreover, the system includes a plunger member coupled to the stopper member and disposed at least partially within the finger flange. In addition, the system includes a thumbpad coupled to a proximal end of finger flange and operatively coupled to the plunger member. The system also includes a cam configured to rotate a predetermined angular distance and a ratchet configured to advance the plunger member a predetermined longitudinal distance with each full advancement of the thumbpad into the finger flange.