Patents by Inventor Alan Edward Royce

Alan Edward Royce has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220031609
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: October 14, 2021
    Publication date: February 3, 2022
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • Publication number: 20210169854
    Abstract: Disclosed are novel pharmaceutical formulation containing 3?-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2?-hydroxy-[1,1?-biphenyl]-3-carboxylic acid or a pharmaceutically acceptable salt thereof and processes for preparing the same.
    Type: Application
    Filed: September 18, 2020
    Publication date: June 10, 2021
    Inventors: Mangesh Sadashiv Bordawekar, Stephanie Kay Dodd, Cornelius Stephan Harlacher, Jithin K John, Pravin Karmuse, Saran Kumar, Sangeetha Kumari, Vishnu Maremanda, Parthkumar Patel, Kanhaiyalal Patidar, Kapil Patil, Alan Edward Royce, Shaikh Mohsin Shaikh Hamid, Mauro Serratoni, Henricus Lambertus Gerardus Maria Tiemessen, Daya D Verma, Sunita Yadav
  • Publication number: 20200237690
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: April 3, 2020
    Publication date: July 30, 2020
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • Publication number: 20190175527
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 13, 2019
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • Publication number: 20170290787
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: June 27, 2017
    Publication date: October 12, 2017
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Patent number: 9622975
    Abstract: The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly (amino acids) such as peptides, peptidomimetics and proteins. e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly (amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: April 18, 2017
    Assignee: Novartis AG
    Inventors: Moise Azria, Simon David Bateman, Anasuya Ashok Ghosh, Shoufeng Li, Alan Edward Royce
  • Publication number: 20150250729
    Abstract: The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly (amino acids) such as peptides, peptidomimetics and proteins. e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly (amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.
    Type: Application
    Filed: May 21, 2015
    Publication date: September 10, 2015
    Inventors: Moise Azria, Simon David Bateman, Anasuya Ashok Ghosh, Shoufeng Li, Alan Edward Royce
  • Publication number: 20140287040
    Abstract: This invention relates to a formulation comprising a dipeptidylpeptidase IV (DPP-IV) inhibitor preferably vildagliptin and metformin, to tablets comprising such formulations and to processes for the preparation thereof.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Applicant: Novartis AG
    Inventors: Yatindra Joshi, James Kowalski, Jay Parthiban Lakshman, Alan Edward Royce, Wei-Qin Tong, Madhav Vasanthavada
  • Publication number: 20140255497
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicant: Novartis AG
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Publication number: 20140011885
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: September 16, 2013
    Publication date: January 9, 2014
    Applicant: Novartis AG
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Publication number: 20130052239
    Abstract: This invention relates to a formulation comprising a dipeptidylpeptidase IV (DPP-IV) inhibitor preferably vildagliptin and metformin, to tablets comprising such formulations and to processes for the preparation thereof.
    Type: Application
    Filed: September 4, 2012
    Publication date: February 28, 2013
    Inventors: Yatindra Joshi, James Kowalski, Jay Parthiban Lakshman, Alan Edward Royce, Wei-Qin Tong, Madhav Vasanthavada
  • Publication number: 20120164218
    Abstract: Monolayer, bilayer and trilayer solid dosage forms of a combination of valsartan, amlodipine and hydrochlorothiazide are made.
    Type: Application
    Filed: January 3, 2012
    Publication date: June 28, 2012
    Inventors: Yu Cao, Yatindra Joshi, Ping Li, Madhusudhan Pudipeddi, Alan Edward Royce, Robert Frank Wagner, Jiahao Zhu
  • Publication number: 20110218148
    Abstract: The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly(amino acids) such as peptides, peptidomimetics and proteins, e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly(amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.
    Type: Application
    Filed: April 4, 2011
    Publication date: September 8, 2011
    Inventors: Moise Azria, Simon David Bateman, Anasuya Ashok Ghosh, Shoufeng Li, Alan Edward Royce
  • Publication number: 20110105620
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 5, 2011
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Publication number: 20110045062
    Abstract: This invention relates to a formulation comprising a dipeptidylpeptidase IV (DPP-IV) inhibitor preferably vildagliptin and metformin, to tablets comprising such formulations and to processes for the preparation thereof.
    Type: Application
    Filed: November 4, 2010
    Publication date: February 24, 2011
    Inventors: Yatindra Joshi, James Kowalski, Jay Parthiban Lakshman, Alan Edward Royce, Wei-Qin Tong, Madhav Vasanthavada
  • Publication number: 20100233253
    Abstract: An extended release gastro-retentive drug delivery system of Valsartan. The drug delivery system contains a release portion containing the Valsartan, a gastro-retentive portion for retaining the drug delivery system in the stomach and an optional secondary portion for delivering a secondary pulse of Valsartan. In another embodiment, there is provided a swellable unfolding membrane comprising Valsartan for sustained administration of Valsartan to the upper GI tract of a patient.
    Type: Application
    Filed: August 29, 2007
    Publication date: September 16, 2010
    Applicant: Novartis AG
    Inventors: Nikhil Javant Kavimandan, Jay Parthiban Lakshman, Arnol Singh Matharu, Joerg Ogorka, Alan Edward Royce, Noel Raj Teelucksingh
  • Publication number: 20100196467
    Abstract: The present invention especially relates to the use of a combination comprising (1) an ACEI selected from the group consisting of benazepril, benazeprilat, and pharmaceutically acceptable salts thereof, and (2) amlodipine or pharmaceutically acceptable salt thereof, for the manufacture a medicament for the treatment or prevention or delay of progression of a condition selected from the group consisting of hypertension, congestive heart failure, angina, myocardial infarction, artherosclerosis, diabetic nephropathy, diabetic cardiac myopathy, renal insufficiency, peripheral vascular disease, left ventricular hypertrophy, cognitive dysfunction, blood pressure-related cerebrovasular disease, stroke, pulmonary disease or pulmonary hypertension and headache; wherein (i) the amount of amlodipine or a pharmaceutically acceptable salt thereof corresponds to 6 about mg to 40 about mg of the free base and (ii) the amount of the ACE inhibitor or a pharmaceutically thereof corresponds to 20 about mg to 160 about mg of
    Type: Application
    Filed: April 16, 2010
    Publication date: August 5, 2010
    Inventors: William Lionel Daley, Randy Lee Webb, Ann Reese Comfort, Santo Joseph Fleres, Alan Edward Royce, William Shifeng Wei
  • Publication number: 20090203798
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: August 13, 2008
    Publication date: August 13, 2009
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Publication number: 20080311188
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) a S1P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: August 11, 2008
    Publication date: December 18, 2008
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Publication number: 20080255048
    Abstract: The present invention provides oral pharmaceutical compositions that enable the successful delivery of drugs in a pharmaceutically effective amount, particularly poly (amino acids) such as peptides, peptidomimetics and proteins, e.g. hormones to a subject via oral administration to accomplish the desired therapeutic effect. The oral pharmaceutical composition comprising a poly (amino acid) as the active ingredient, e.g. a peptide or protein, shows a rapid disintegration and/or dissolution such that the active ingredient is able to attain a therapeutic effect.
    Type: Application
    Filed: November 16, 2006
    Publication date: October 16, 2008
    Inventors: Moise Azria, Simon David Bateman, Anasuya Ashok Ghosh, Shoufeng Li, Alan Edward Royce