Abstract: A method and system for constructing and delivering wireless networking, according to some embodiments. Some embodiments embed wireless transceivers into light bulbs and small wall-pluggable devices. Some embodiments use a strip or plane of material embedded with wireless transceivers, power, and networking. Some embodiments use a strip or plane of material embedded with antennas, often switchable. In some embodiments, multiple Wi-Fi systems are surface mounted on a strip that includes networking and power. In some embodiments, a head end is used to interface the strip to the remainder of the network and the main power supply. An over deployment resource manager is disclosed.

Abstract: Methods and systems are disclosed for an antenna system capable of optimal broadside radiation. In certain embodiments, a system may include a flexible and thin polyethylene terephthalate (PET) substrate stack having a predetermined length. The system may include a printed circuit board (PCB) fabrication of one or more Leaky-Wave Antenna (LWA) structures on the PET substrate stack. The one or more LWA structures have a bent-stub folded LWA configuration have longitudinal asymmetry and transverse asymmetry for a broadside frequency. The bent-stub folded LWA configuration comprises a plurality of conductively unit cells having a unit cell period. Each unit cell of the plurality of conductively unit cells has a folded main feed-line and a bent stub pair with two angularly bent radiating stubs. Embodiments are structured to increase radiation per-unit length and suppress open stopband (OSB).

Abstract: Applicant discloses herein an immunoconjugate, which enables systemic use of targeted CpG using a new class of antibodies which target the tumor microenvironment. Conjugation to checkpoint inhibitors such as anti-PD-L1, anti-CTLA-4, anti-LAGS anti-TIM-3, and anti-VISTA to make “biobetter” reagents.

Abstract: A method and system providing medical treatment to patients. In some embodiments, a patient is granted clinically sufficient access to their underlying health records and is able to observe and place treatment orders. In some embodiments, a patient and a practitioner are able to collaborate on the patient's treatments. In some embodiments, a practitioner is summoned from a pool of practitioners. In some embodiments, a change manager tracks changes to the underlying medical treatment plan for potential review, approval, modification, or rejection. Further embodiments provide a collaboration or supervision interface between patients and automated medical decision or practice systems, such as robodocs.

Abstract: In accordance with some embodiments, a method and system for establishing the trustworthiness of software and running systems by analyzing software and its provenance using automated means. In some embodiments, a risk score is produced. In some embodiments, software is analyzed for insecure behavior or structure. In some embodiments, parts of the software are hardened by producing possibly multiple different versions of the software with different hardening techniques applied, and a choice can be made based on user or environmental needs. In some embodiments, the software is verified and constraints are enforced on the endpoint using techniques such as verification injection and secure enclaves. In some embodiments, endpoint injection is managed through container orchestration.

Abstract: Humanized monoclonal anti-nuclear antibodies with enhanced binding affinity and tumor uptake are presented. Particularly preferred antibodies are site-directed mutants of H-CDR3 with up to about 8-fold improvement in affinity as compared to the non-humanized non-mutated form. In further preferred aspects, such humanized antibodies are employed in tumor necrosis targeted delivery of immune modulators, immune effectors, and other therapeutic or diagnostic agents.

Abstract: In accordance with some embodiments, a method and system for establishing the trustworthiness of software and running systems by analyzing software and its provenance using automated means. In some embodiments, a risk score is produced. In some embodiments, software is analyzed for insecure behavior or structure. In some embodiments, parts of the software are hardened by producing possibly multiple different versions of the software with different hardening techniques applied, and a choice can be made based on user or environmental needs. In some embodiments, the software is verified and constraints are enforced on the endpoint using techniques such as verification injection and secure enclaves. In some embodiments, endpoint injection is managed through container orchestration.

Abstract: A method and system providing medical treatment to patients. In some embodiments, a remote practitioner is connected via a referral network to an in-person clinician that can perform work that cannot be performed remotely on behalf of the practitioner. Some embodiments perform a lightweight referral for said work, where the work may be smaller than the minimum procedure code and assigned billing for the overall specific therapy being undertaken. In some embodiments, the in-person clinician is only licensed to be able to perform the tasks they are assigned. In some embodiments, the in-person clinicians operate as the remote in-person medical assistance needed for the remote practitioner to practice medicine. Billing and pricing methods are disclosed for sub-procedure-code tasks.

Abstract: A method for configuring a flexible wireless networking system is disclosed. The system may include multiple Wi-Fi transceivers coupled to each other in parallel and selectively couplable to one or more antennas by respective switches. The method may include obtaining topology information indicating whether and how each antenna is in reach of other antennas, determining, dependent on the topology information, a configuration change including a change in which and how many of the antennas are coupled to the Wi-Fi transceivers, and initiating an activation of a switch to couple one of the antennas to one of the Wi-Fi transceivers or a deactivation of a switch to decouple one of the antennas from one of the Wi-Fi transceivers. The configuration change may be determined using a machine learning model. The configuration change may include deactivating a currently active antenna and activating at least one alternate antenna having a different coverage area.

Abstract: Humanized monoclonal anti-nuclear antibodies with enhanced binding affinity and tumor uptake are presented. Particularly preferred antibodies are site-directed mutants of H-CDR3 with up to about 8-fold improvement in affinity as compared to the non-humanized non-mutated form. In further preferred aspects, such humanized antibodies are employed in tumor necrosis targeted delivery of immune modulators, immune effectors, and other therapeutic or diagnostic agents.

Abstract: A method and system for detecting speech using close sensor applications, according to some embodiments. In some embodiments, a close microphone is applied to detect sounds with higher muscle or bone transmission components. In some embodiments, a close camera is applied that collects visual information and motion that is correlated with the potential phonemes for such positions and motion. In some embodiments, myography is performed, to detect muscle movement. In an earbud form factor embodiment, processing of different channels of close information is performed to improve the accuracy of the recognition.

Abstract: In one embodiment, a wireless network system includes a set of one or more wireless radios, and a set of software for the wireless network system that comprises a data structure representing the set of one or more wireless radios and a virtualization module that registers one or more virtualized data structures representing a virtual proxy of the set of one or more wireless radios.

Abstract: Systems and methods for providing access to a wireless network include apparatus and manufacturing and configuration techniques. Embodiments include a head-end configured to receive electrical power and communicate with the wireless network. In an embodiment, a plurality of integrated access points each comprise components such as a radio, a power supply, a controller, a network transceiver, and an antenna. The components of each integrated access point, whether or not they are assembled on one or more rigid or flexible cards, may be embedded in a material expanse such as a flexible strip, upon which each set of components may be proximally integrated. In an embodiment, a system includes a unified backplane interconnect coupled to the head-end, the unified backplane interconnect comprising a plurality of interconnects. Each integrated access point may comprise a single radio, or more than one radio.

Abstract: A method and system for constructing and delivering wireless networking, according to some embodiments. Some embodiments embed wireless transceivers into light bulbs and small wall-pluggable devices. Some embodiments use a strip or plane of material embedded with wireless transceivers, power, and networking. Some embodiments use a strip or plane of material embedded with antennas, often switchable. In some embodiments, multiple Wi-Fi systems are surface mounted on a strip that includes networking and power. In some embodiments, a head end is used to interface the strip to the remainder of the network and the main power supply. An over deployment resource manager is disclosed.

Abstract: A method and system providing medical treatment to patients. In some embodiments, a patient is granted clinically sufficient access to their underlying health records and is able to observe and place treatment orders. In some embodiments, a patient and a practitioner are able to collaborate on the patient's treatments. In some embodiments, a practitioner is summoned from a pool of practitioners. In some embodiments, a change manager tracks changes to the underlying medical treatment plan for potential review, approval, modification, or rejection. Further embodiments provide a collaboration or supervision interface between patients and automated medical decision or practice systems, such as robodocs.

Abstract: A method and system providing medical treatment to patients. In some embodiments, a remote practitioner is connected via a referral network to an in-person clinician that can perform work that cannot be performed remotely on behalf of the practitioner. Some embodiments perform a lightweight referral for said work, where the work may be smaller than the minimum procedure code and assigned billing for the overall specific therapy being undertaken. In some embodiments, the inperson clinician is only licensed to be able to perform the tasks they are assigned. In some embodiments, the in-person clinicians operate as the remote in-person medical assistance needed for the remote practitioner to practice medicine. Billing and pricing methods are disclosed for sub-procedure-code tasks.

Abstract: A method and system for aiding in the diagnosis and treatment of medical and health conditions. In some embodiments, a risk profiler analyzes population incidence statistics with test results to populate an interactive simulation and decision engine. Further embodiments produce treatment betting tables. In some embodiments, diagnosis fact boxes are produced. Users, such as clinicians and patients, interact with the simulation and decision engine to explore different diagnosis possibilities and treatment options, with feedback showing the statistical likelihoods and consequences of the possibilities.

Abstract: A method and system for detecting speech using close sensor applications, according to some embodiments. In some embodiments, a close microphone is applied to detect sounds with higher muscle or bone transmission components. In some embodiments, a close camera is applied that collects visual information and motion that is correlated with the potential phonemes for such positions and motion. In some embodiments, myography is performed, to detect muscle movement. In an earbud form factor embodiment, processing of different channels of close information is performed to improve the accuracy of the recognition.

Abstract: Humanized monoclonal anti-nuclear antibodies with enhanced binding affinity and tumor uptake are presented. Particularly preferred antibodies are site-directed mutants of H-CDR3 with up to about 8-fold improvement in affinity as compared to the non-humanized non-mutated form. In further preferred aspects, such humanized antibodies are employed in tumor necrosis targeted delivery of immune modulators, immune effectors, and other therapeutic or diagnostic agents.

Abstract: compositions and methods employ an anti-nucleolin antibody or fragment thereof to specifically target necrotic tumor cells. Thus, and in preferred aspects, compositions and methods may be used to target the tumor microenvironment and cancer cells within such milieu. Also included are methods of targeting necrotic cells with binding agent that specifically binds nucleolin.