Patents by Inventor Alan F. Haughan

Alan F. Haughan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HTT modulators for treating Huntington's disease
    Patent number: 11806346
    Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: November 7, 2023
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Elizabeth M. Doherty, Longbin Liu, Matthew Lee, Mark Stuart Chambers, Karine Fabienne Malagu, Perla Breccia, Alan F. Haughan, Huw D. Vater, Andrew J. Stott, William R. K. Esmieu, Stephen John Webster, Amanda J. Van De Poël
  • HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE
    Publication number: 20220409615
    Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.
    Type: Application
    Filed: May 12, 2021
    Publication date: December 29, 2022
    Inventors: Celia Dominguez, Elizabeth M. Doherty, Longbin Liu, Matthew Lee, Mark Stuart Chambers, Karine Fabienne Malagu, Perla Breccia, Alan F. Haughan, Huw D. Vater, Andrew J. Stott, William R. K. Esmieu, Stephen John Webster, Amanda J. Van De Poël
  • RHO KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20220388998
    Abstract: Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 8, 2022
    Inventors: Michel C. Maillard, Matthew R. Lee, Celia Dominguez, Michael Barnes, Alan F. Haughan, Tammy Ladduwahetty, Christopher A. Luckhurst, Andrew J. Stott, Jason Tierney
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10457675
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: October 29, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20190202795
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: July 26, 2018
    Publication date: July 4, 2019
    Inventors: Michel C. Maillard, Perla Breccia, Celia Dominguez, Alan F. Haughan, Amanda Van de Poël, Andrew J. Stott, Christopher A. Luckhurst, Elizabeth A. Saville-Stones, Grant Wishart, Michael Wall, Rebecca E. Jarvis
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20190185463
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: July 26, 2018
    Publication date: June 20, 2019
    Inventors: Michel C. Maillard, Perla Breccia, Celia Dominguez, Alan F. Haughan, Rebecca E. Jarvis, Christopher A. Luckhurst, Elizabeth A. Saville-Stones, Andrew J. Stott, Amanda Van de Poël, Michael Wall, Grant Wishart
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20190062321
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Application
    Filed: July 30, 2018
    Publication date: February 28, 2019
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10106535
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: October 23, 2018
    Assignee: CHDI FOUNDATION, INC.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10105363
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: October 23, 2018
    Assignee: CHDI foundation, Inc.
    Inventors: Celia Dominguez, Vahri Beaumont, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Alan F. Haughan, Christopher A. Luckhurst, Michael Wall, Gilles Raphy, Beth Thomas
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10065948
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: September 4, 2018
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10053434
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: August 21, 2018
    Assignee: CHDI FOUNDATION, INC.
    Inventors: Michel C. Maillard, Perla Breccia, Celia Dominguez, Alan F. Haughan, Amanda Van de Poël, Andrew J. Stott, Christopher A. Luckhurst, Elizabeth A. Saville-Stones, Grant Wishart, Michael Wall, Rebecca E. Jarvis
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10047073
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: August 14, 2018
    Assignee: CHDI FOUNDATION, INC
    Inventors: Michel C. Maillard, Perla Breccia, Celia Dominguez, Alan F. Haughan, Rebecca E. Jarvis, Christopher A. Luckhurst, Elizabeth A. Saville-Stones, Andrew J. Stott, Amanda Van de Poël, Michael Wall, Grant Wishart
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170305900
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: April 7, 2017
    Publication date: October 26, 2017
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9783488
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 10, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Gilles Raphy, Alan F. Haughan, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Perla Breccia, Grant Wishart, Samantha J. Hughes, Daniel R. Allen, Stephen D. Penrose
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9765054
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: September 19, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Roland W. Bürli, Andrew J. Stott, Perla Breccia, Celia Dominguez, Ignacio Muñoz-Sanjuàn, Christopher A. Luckhurst, Samantha J. Hughes, Alan F. Haughan
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170224684
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: January 20, 2017
    Publication date: August 10, 2017
    Inventors: Celia Dominguez, Vahri Beaumont, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Alan F. Haughan, Christopher A. Luckhurst, Michael Wall, Gilles Raphy, Beth Thomas
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170101402
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
    Type: Application
    Filed: June 1, 2015
    Publication date: April 13, 2017
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Roland W. Bürli, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebeca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9617259
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: April 11, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9562021
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: February 7, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Vahri Beaumont, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Alan F. Haughan, Christopher A. Luckhurst, Michael Wall, Gilles Raphy, Beth Thomas
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20160333001
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: May 6, 2016
    Publication date: November 17, 2016
    Inventors: Celia Dominguez, Michel C. Maillard, Perla Breccia, Alan F. Haughan, Rebecca E. Jarvis, Christopher A. Luckhurst, Elizabeth A. Saville-Stones, Andrew J. Stott, Amanda Van de Poël, Michael Wall, Grant Wishart