Patents by Inventor Alan Frederick Cowman

Alan Frederick Cowman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and Methods for Modulating an Immune Response
    Publication number: 20150265721
    Abstract: The present invention relates to the identification of proteins which bind the dendritic cell marker known as Clec9A. The present invention provides new compounds for targeting therapeutic agents such as antigens to dendritic cells. Also provided are methods of modulating a humoral and/or T cell mediated immune response to the antigen, methods of delivery of a cytotoxic agent to dendritic cells thereof involved in diseased states, methods of modulating the uptake and/or clearance of cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof, and methods of modulating antigen recognition, processing and/or presentation, as well as immune responses to material derived from cells with a disrupted cell membrane, cells infected with a pathogen, dying cells or dead cells, or a portion thereof.
    Type: Application
    Filed: December 23, 2014
    Publication date: September 24, 2015
    Inventors: Mireille Hanna Lahoud, Irina Caminschi, Ken Shortman, Jian-Guo Zhang, Mark Francis Van Delft, David Ching Siang Huang, Nicos Anthony Nicola, Alan Frederick Cowman, Mark Dexter Wright
  • Live genetically attenuated malaria vaccine
    Patent number: 8168166
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: May 1, 2012
    Assignees: Seattle Biomedical Research Institute, Walter and Eliza Hall Institute of Medical Research
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • LIVE GENETICALLY ATTENUATED MALARIA VACCINE
    Publication number: 20110033502
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: May 6, 2008
    Publication date: February 10, 2011
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier