Patents by Inventor Alan Fulp
Alan Fulp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8338608Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: GrantFiled: March 22, 2010Date of Patent: December 25, 2012Assignee: Icagen Inc.Inventors: Xiaodong Wang, Alan Fulp, Brian Marron, Serge Beaudoin, Darrick Seconi, Mark Suto
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Patent number: 8063080Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides heterocyclic aryl sulfonamides, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: GrantFiled: September 16, 2009Date of Patent: November 22, 2011Assignee: Icagen, Inc.Inventors: Alan Fulp, Brian Marron, Mark J. Suto, Xiaodong Wang
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Publication number: 20100234343Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: ApplicationFiled: March 22, 2010Publication date: September 16, 2010Applicant: Icagen, Inc.Inventors: Xiaodong Wang, Alan Fulp, Brian Marron, Serge Beaudoin, Darrick Seconi, Mark Suto
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Patent number: 7705158Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: GrantFiled: November 2, 2006Date of Patent: April 27, 2010Assignee: Icagen, Inc.Inventors: Xiaodong Wang, Alan Fulp, Brian Marron, Serge Beaudoin, Darrick Seconi, Mark Suto
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Publication number: 20100041707Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides heterocyclic aryl sulfonamides, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: ApplicationFiled: September 16, 2009Publication date: February 18, 2010Applicant: Icagen, Inc.Inventors: Alan Fulp, Brian Marron, Mark J. Suto, Xiaodong Wang
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Patent number: 7615569Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides heterocyclic aryl sulfonamides, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: GrantFiled: August 11, 2006Date of Patent: November 10, 2009Assignee: Icagen, Inc.Inventors: Alan Fulp, Brian Marron, Mark J. Suto, Xiaodong Wang
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Publication number: 20090013497Abstract: Disclosed is a pull strap assembly for attaching to a sliding closure such as a door on the rear of a semitrailer. The pull strap assembly comprises a first band attached to the sliding closure and a second band attached to the first band to prevent the first band from hanging out of the cargo enclosure when the sliding closure is in the closed position.Type: ApplicationFiled: July 12, 2007Publication date: January 15, 2009Inventors: Jerrell P. Squyres, Kelly Lee Miller, Keith Alan Fulp
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Publication number: 20070135493Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: ApplicationFiled: November 2, 2006Publication date: June 14, 2007Applicant: IcagenInventors: Xiaodong Wang, Alan Fulp, Brian Marron, Serge Beaudoin, Darrick Seconi, Mark Suto
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Publication number: 20070078145Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides heterocyclic aryl sulfonamides, compositions and methods that are useful in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.Type: ApplicationFiled: August 11, 2006Publication date: April 5, 2007Applicant: IcagenInventors: Alan Fulp, Brian Marron, Mark Suto, Xiaodong Wang
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Publication number: 20070027200Abstract: The present invention provides a genus of bis-benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: September 29, 2006Publication date: February 1, 2007Applicant: ICAGEN, INC.Inventors: Xiaodong Wang, Alan Fulp, Albert van Rhee, Kerry Spear
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Publication number: 20060178346Abstract: The present invention provides a class of chemical compounds useful in the treatment of sickle cell disease, diseases characterized by unwanted or abnormal cell proliferation and for the treatment of ocular disorders such as glaucoma. The active compounds are tri-(aryl or heteroaryl) methane compounds or analogues thereof which further comprise an imine moiety and where the tertiary carbon atom can be replaced with a different atom such as Si, Ge, N or P. The compounds enhance resistance to degradation in a biological medium, inhibit potassium flux in a cell, reduce mammalian cell proliferation, reduce the Gardos channel of erythrocytes, reduce sickle erythrocyte dehydration and/or delay the occurrence of erythrocyte sickling or deformation.Type: ApplicationFiled: February 1, 2006Publication date: August 10, 2006Applicant: ICAgen, Inc.Inventors: Xiaodong Wang, Alan Fulp, Darrick Seconi
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Publication number: 20050267089Abstract: The present invention provides a genus of polycyclic pyrimidines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: April 13, 2005Publication date: December 1, 2005Applicants: ICAgen, Inc., Astellas Pharma Inc.Inventors: Xiaodong Wang, Kerry Spear, Alan Fulp, Darrick Seconi, Takeshi Suzuki, Takahiro Ishii, Ayako Moritomo
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Publication number: 20050267032Abstract: Compounds, compositions and methods are provided which are useful in the treatment of diseases through the modulation of potassium ion flux through voltage-dependent potassium channels. More particularly, the invention provides sulfone-containing prodrugs, and compositions and methods utilizing sulfone-containing prodrugs that are useful in the treatment of diseases by blocking potassium channels associated with the onset or recurrence of the indicated conditions. Exemplary diseases treatable with the compounds, compositions and methods of the invention include sickle cell disease and glaucoma.Type: ApplicationFiled: May 23, 2005Publication date: December 1, 2005Applicant: Icagen, Inc.Inventors: Alan Fulp, Grant McNaughton-Smith, Aimee Reed, Xiadong Wang
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Publication number: 20050239800Abstract: The present invention provides a genus of polycyclic pyrazines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: April 13, 2005Publication date: October 27, 2005Applicants: ICAgen, Inc., Astellas Pharma Inc.Inventors: Xiaodong Wang, Kerry Spear, Alan Fulp, Darrick Seconi, Takeshi Suzuki, Takahiro Ishii, Ayako Moritomo
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Publication number: 20050227958Abstract: The present invention provides a genus of polycyclic pyridines that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: April 13, 2005Publication date: October 13, 2005Applicant: ICAgen, Inc.Inventors: Xiaodong Wang, Kerry Spear, Alan Fulp, Darrick Seconi
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Publication number: 20050227989Abstract: The present invention provides a genus of polycyclic thiazoles that are useful as modulators of potassium ion channels. The modulators of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: April 13, 2005Publication date: October 13, 2005Applicants: ICAgen, Inc., Astellas Pharma Inc.Inventors: Xiaodong Wang, Kerry Spear, Alan Fulp, Darrick Seconi, Takeshi Suzuki, Takahiro Ishii, Ayako Moritomo, Hideki Kubota
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Publication number: 20050038067Abstract: The present invention provides a genus of asymmetric benzimidazole compounds, methods and pharmaceutical compositions that are useful as modulators of potassium ion channels. The compounds of the invention are of use in both therapeutic and diagnostic methods.Type: ApplicationFiled: May 12, 2004Publication date: February 17, 2005Applicant: Icagen, Inc.Inventors: Xiaodong Wang, Alan Fulp