Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: Systems, methods, and computer-readable media for evaluating a set of computed tomography data associated with a lattice structure. The lattice structure may be additively manufactured. The computed tomography data may be segmented using a filter for identifying blob-like structures to identify nodes present within the lattice structure. A three-dimensional path traversal is applied to volumetric data to identify a plurality of struts within the lattice structure that are compared to corresponding struts within a set if three-dimensional mesh data of the lattice structure to identify defective struts. Further, two-dimensional slices may be extracted from each of the computed tomography data and the mesh data and compared to identify one or more inconsistencies indicative of defects within the lattice structure.

Abstract: Systems, methods, and computer-readable media for evaluating a set of computed tomography data associated with a lattice structure. The lattice structure may be additively manufactured. The computed tomography data may be segmented using a filter for identifying blob-like structures to identify nodes present within the lattice structure. A three-dimensional path traversal is applied to volumetric data to identify a plurality of struts within the lattice structure that are compared to corresponding struts within a set if three-dimensional mesh data of the lattice structure to identify defective struts. Further, two-dimensional slices may be extracted from each of the computed tomography data and the mesh data and compared to identify one or more inconsistencies indicative of defects within the lattice structure.

Abstract: Systems, methods, and computer-readable media for evaluating a set of computed tomography data associated with a lattice structure. The lattice structure may be additively manufactured. The computed tomography data may be segmented using a filter for identifying blob-like structures to identify nodes present within the lattice structure. A three-dimensional path traversal is applied to volumetric data to identify a plurality of struts within the lattice structure that are compared to corresponding struts within a set if three-dimensional mesh data of the lattice structure to identify defective struts. Further, two-dimensional slices may be extracted from each of the computed tomography data and the mesh data and compared to identify one or more inconsistencies indicative of defects within the lattice structure.

Abstract: Systems, methods, and computer-readable media for evaluating a set of computed tomography data associated with a lattice structure. The lattice structure may be additively manufactured. The computed tomography data may be segmented using a filter for identifying blob-like structures to identify nodes present within the lattice structure. A three-dimensional path traversal is applied to volumetric data to identify a plurality of struts within the lattice structure that are compared to corresponding struts within a set if three-dimensional mesh data of the lattice structure to identify defective struts. Further, two-dimensional slices may be extracted from each of the computed tomography data and the mesh data and compared to identify one or more inconsistencies indicative of defects within the lattice structure.

Abstract: The present invention relates to a method and system for providing a loyalty program. The method includes a user providing access to a server to a plurality of receipts from a plurality of providers. The server processes the receipts in order to generate benefits for the user.

Abstract: Aspects of the present invention relate to path determination for transport system infrastructure paths. In embodiments, methods and systems are provided for identifying alternative paths and determining optimized transport system paths for projects. The methods and systems may involve providing a client-based application having a GUI that presents a plurality of constraints that relate to a project, a server-based application for calculating the costs of a plurality of potential paths for presenting a subset of paths with associated cost data, and determining optimized paths for at least one of a pipeline, a conveyor, a canal, a multipurpose utility pipe, and a telecommunication line.

Abstract: Aspects of the present invention relate to path determination for vehicle infrastructure paths. In embodiments, methods and systems are provided for identifying alternative paths and determining optimized vehicle paths for projects.

Abstract: Aspects of the present invention relate to path determination for transport system infrastructure paths. In embodiments, methods and systems are provided for identifying alternative paths and determining optimized transport system paths for projects. The methods and systems may involve providing a client-based application having a GUI that presents a plurality of constraints that relate to a project, a server-based application for calculating the costs of a plurality of potential paths for presenting a subset of paths with associated cost data, and determining optimized paths for at least one of a pipeline, a conveyor, a canal, a multipurpose utility pipe, and a telecommunication line.

Abstract: Aspects of the present invention relate to a client-based application and server-based application for providing optimized corridors and alignments, routes, and or paths subject to a plurality of constraints. In embodiments, methods and systems are provided for identifying alternative paths and determining optimized paths for projects. The methods and systems may involve providing a client-based application having a GUI that presents a plurality of constraints that relate to a project, and a server-based application for calculating the costs of a plurality of potential paths for presenting a subset of paths with associated cost data.

Abstract: Aspects of the present invention relate to providing control for a secure infrastructure of a path determination system. In embodiments, methods and systems are provided for controlling objects in a computer-based system. The methods and systems may involve storing an object in the system, the object being related to data about the path or project, assigning an encryption key for each aspect of the system or object desired to be controlled, encrypting each aspect of the system or object desired to be controlled, requiring entry of the encryption key corresponding to each aspect of the system or object desired to be released from the control, and distributing the encryption key.

Abstract: Aspects of the present invention relate to a client-based graphical user interface for infrastructure path determination. In embodiments, methods and systems are provided for a user interface and remote infrastructure planning. Methods and systems provide a user interface for allowing a user to select an object that relates to the determination of a path and upon selection of the object, triggering an action of a path determination system. Methods and systems are provided for establishing a connection to a portable computer device, accessing an infrastructure model remotely from the portable computer device, and interacting with the infrastructure model using the portable computer device.

Abstract: A cooling air cooling system is selectively operable to reduce fuel gum deposits within the cooling system during gas turbine engine operations. The cooling system includes a recirculating loop that includes at least three heat exchangers in fluid communication with the recirculating loop. A first heat exchanger cools cooling air supplied to the gas turbine engine. A second heat exchanger cools fluid exiting the first of the heat exchangers with fan discharge air prior to the fluid entering the third heat exchanger. A third heat exchanger uses combustor main fuel flow to cool the fluid circulating in the recirculating loop.