Patents by Inventor Alan H. Auerbach

Alan H. Auerbach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220133749
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17, 20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: January 19, 2022
    Publication date: May 5, 2022
    Inventors: Alan H. Auerbach, Arie S. Belldegrun, Johann de Bono
  • Publication number: 20200237785
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: April 14, 2020
    Publication date: July 30, 2020
    Inventors: Alan H. Auerbach, Arie S. Belldegrun, Johann de Bono
  • Patent number: 10702540
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17, 20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: July 7, 2020
    Assignees: Janssen Oncology, Inc., British Technology Group Limited
    Inventors: Alan H. Auerbach, Arie S. Belldegrun, Johann de Bono
  • Publication number: 20180000840
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17, 20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: September 13, 2017
    Publication date: January 4, 2018
    Inventors: Alan H. Auerbach, Arie S. Belldegrun, Johann de Bono
  • Publication number: 20170136042
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods tor treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: Alan H. Auerbach, Arie S. Belldegrun
  • Publication number: 20160151394
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Alan H. Auerbach, Arie S. Belldegrun
  • Publication number: 20150290221
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e. 3?-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: June 25, 2015
    Publication date: October 15, 2015
    Inventors: Alan H Auerbach, Arie S. Belldegrun
  • Publication number: 20150005268
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: September 12, 2014
    Publication date: January 1, 2015
    Inventors: Alan H. Auerbach, Arie S. Belldegrun
  • Publication number: 20140336157
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl)androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: July 28, 2014
    Publication date: November 13, 2014
    Inventors: Alan H. Auerbach, Arie S. Belldegrun
  • Patent number: 8822438
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl)androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: September 2, 2014
    Assignee: Janssen Oncology, Inc.
    Inventors: Alan H. Auerbach, Arie S. Belldegrum
  • Publication number: 20110144016
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e., 3?-acetoxy-17-(3-pyridyl) androsta-5,16-diene), in combination with at least one additional therapeutic agent such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17?-hydroxylase/C17,20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.
    Type: Application
    Filed: February 24, 2011
    Publication date: June 16, 2011
    Inventors: Alan H. Auerbach, Arie S. Belldegrum
  • Publication number: 20110021470
    Abstract: Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a vitamin D compound in combination with at least one additional therapeutic agent, such as an anti-cancer agent or a steroid. Furthermore, disclosed are compositions comprising vitamin D compounds and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid, e.g., corticosteroid or more specifically, a glucocorticoid.
    Type: Application
    Filed: October 5, 2010
    Publication date: January 27, 2011
    Inventors: Alan H. Auerbach, Arie S. Belldegrun
  • Publication number: 20090124587
    Abstract: Methods for treating certain cancers in patients, such as mammals, using certain 17?-hydroxylase/C17,20-lyase inhibitors are discussed herein. More particularly, methods for treating cancers comprising administering a 17?-hydroxylase/C17,20-lyase inhibitor, such as abiraterone acetate (i.e. 3?-acetoxy-17-(3-pyridyl) androsta-5,16-diene) and metabolites thereof are described. In addition, methods for treating cancers that are refractory to hormone therapy or that are refractory to chemotherapy are also discussed. Finally novel dosing regimens and novel uses of the compounds discussed herein are disclosed.
    Type: Application
    Filed: July 11, 2008
    Publication date: May 14, 2009
    Inventors: Alan H. Auerbach, Arie S. Belldegrun