Abstract: The present disclosure relates to monovalent antibodies and chimeric proteins (comprising the monovalent antibodies) for the treatment of an auto-immune inflammatory disorder or condition. The monovalent antibody moiety lacks a Fc region, is specific for an activating Fc receptor and is for limiting or avoiding the activation of an immune cell induced in the presence and upon the binding of a ligand of the activating Fc receptor to the activating Fc receptor. The monovalent antibodies and chimeric proteins are especially useful for the prevention, treatment or alleviation of symptoms associated with an auto-immune inflammatory disorder caused or maintained by the engagement of an auto-antibody having a Fc region capable of engaging the activating Fc receptor to mediate the pathological destructions of cells or tissues.

Abstract: A method of cell-based therapy for treating an autoimmune disease is disclosed. The method is directed at stimulating leukocytes and/or dendritic cells to interrupt autoimmunity in a host. The method provides a Fc? receptor-specific complex or a complex which results in the co-crosslinking of Fc?-chains for treating the leukocytes and/or dendritic cells which are in turn used to elicit an autoimmune interruption response in a subject with an autoimmune disease. The Fc? receptor-specific complex and/or complex which results in the co-crosslinking of Fc?-chains is used to treat a biological sample comprising leukocytes and/or dendritic cells from a patient, and upon reintroducing said biological sample to the patient, the pre-treated dendritic cells illicit an autoimmune interruption response in vivo.

Abstract: A method for treating autoimmune diseases in a mammal which method comprises administering to the mammal an effective amount of at least one antibody specific for a soluble antigen is provided. Furthermore, a novel mechanism of action has been established in accordance with the present invention for antibody-based treatment regimes for autoimmune disease, including but not limited to anti-CD44 and soluble antigen specific antibody treatment regimes.

Abstract: The invention relates to a method for inhibiting an in vivo alloimmune response, and to the use of a soluble recombinant human CD40L protein containing the active binding site with CD40. In particular, a soluble 18 KDa recombinant CD40L is used to inhibit an in vivo alloimmune response.

Abstract: The present invention relates to a method for preventing HLA alloimmune response to platelet transfusion. The method comprises the step of presensitizing platelets with at least one monoclonal HLA antibody. The platelets if administered to a patient prevent an HLA alloimmune response from said patient.

Abstract: The present invention relates to a method and composition utilizing monoclonal intravenous immunoglobulin (mIVIG) for increasing platelet cell counts in thrombocytopenia. The method and composition are suitable for treatments of patients suffering from medical conditions, such as idiopathlic thrombocytopenic purpura (ITP), which result in low platelet cell numbers.

Abstract: A sport glove finger construction utilizing an asymmetrical pattern resulting in a seam which lies above the tip and on the back of the fingernail of the user.

Abstract: An improvement in the construction of a sports glove having a thumb cross seam located on the back of the thumbnail covering portion and having a lateral seam located on the back of the thumb joining two thumb covering wing sections, the improvement comprising a panel of material inserted on the inner surface of the thumb bridging and attached to the wing sections to replace the lateral seam.

Abstract: A sport glove thumb portion wherein the joining inseam is asymmetrical and located above the tip and on the back of the thumb. A pattern and seam arrangement are also disclosed.

Abstract: A sport glove thumb portion wherein the joining seam is asymmetrical and located above the tip and on the back of the thumb. A pattern and seam arrangement are also disclosed.