Patents by Inventor Alan H. Sharp

Alan H. Sharp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Huntingtin-associated protein-related assays
    Patent number: 6093549
    Abstract: Proteins which specifically bind to huntingtin, the product of the Huntington's Disease locus (HD), are used in assays for screening drug candidates. These proteins, termed huntingtin associated proteins, bind to huntingtins of both normal and Huntington's Disease patients. However, the binding is stronger to the huntingtins from the patients. The strength of binding correlates with the number of glutamine repeats in the huntingtin, which itself correlates with the time of disease onset.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: July 25, 2000
    Assignee: The Johns Hopkins University
    Inventors: Christopher A. Ross, Xiao-Jiang Li, Shi-Hua Li, Alan H. Sharp, Anthony Lanahan, Paul F. Worley, Solomon H. Snyder