Abstract: A pump side part for use with a centrifugal slurry pump for pumping a fluid mixture containing particulate matter, the pump side part comprising a main body having a main axis, the main body including a side wall section which extends laterally with respect to the main axis and has opposite facing first and second sides, a plurality of formations on a surface of the second side including an inner formation and an outer formation in spaced relation to the inner formation, the formations being configured so that in use the formations generate a flow of the fluid mixture across the surface which detaches from the surface the particulate matter adjacent thereto.

Abstract: A pump side part for use with a centrifugal slurry pump for pumping a fluid mixture containing particulate matter, the pump side part comprising a main body having a main axis, the main body including a side wall section which extends laterally with respect to the main axis and has opposite facing first and second sides, a plurality of formations on a surface of the second side including an inner formation and an outer formation in spaced relation to the inner formation, the formations being configured so that in use the formations generate a flow of the fluid mixture across the surface which detaches from the surface the particulate matter adjacent thereto.

Abstract: A vehicle tailgate includes an upper panel, lower panel, internal panel, external panel and brace. The upper and lower panels are spaced apart relative to each other. The internal and external panels are each secured to the upper and lower panels. A cavity is defined between the upper, lower, internal, and external panels. The brace is disposed within the cavity. The brace includes first and second flanges extending outward from a central plate. The first and second flanges are secured to the internal panel while the central plate is secured to the external panel.

Abstract: This invention relates to the ?2-adrenoceptor agonist Olodaterol or a pharmaceutically acceptable salt thereof, for use in a method of treatment for improvement of exercise tolerance and/or in an improvement of endurance time.

Abstract: An improved open end wrench having wrench heads at both ends of a shank whereon both wrench heads have arcuate surfaces and backup jaws coplanar with a common torqueing jaw whereby the torqueing jaw is a machined surface of the wrench shank that extends into the wrench heads and is terminated at reliefs at a depth less than half the thickness of the shank, at the intersection of the arcuate surfaces and said torqueing jaw, therein, when excessive torque is applied the relief tends to close whereby the backup jaw and torqueing jaw become nonplanar to each other, therefore wedging the polygonal fastener being worked.

Abstract: An open end wrench having a shank with a smooth planar side, the length of the shank, that functions as a torqueing jaw of opposed wrench heads formed at opposite ends of said shank. The opposing wrench heads are each defined by two jaws, one of which is the smooth planar surface of the shank, and an arcuate throat interconnecting the jaws.

Abstract: Silencing equipment is provided for an air-cooling assembly in a large off-road vehicle having wheels, traction motors for the wheels that operate in a motoring mode to propel the vehicle and a power generating dynamic braking mode, resistor grids for dissipating the dynamic braking power, and a blower for moving cooling air past the grids to cool them. The silencing equipment may include a resistor grid housing 24 and at least one upper inlet 22 for passing cooling air to the interior of the housing. The inlet includes noise-absorbing material. A conduit 28 is provided for directing cooling air from the upper inlet through a transition chamber to reach the blower and at least one resistor grid in the housing. The conduit is lined with noise-absorbing material. A removable cover 30 is provided for the conduit for accessing the air blower in the housing through the transition chamber, whereby servicing of the blower may be performed without removal of the entire upper inlet.

Abstract: A method of making a set of labelled compounds by the use of a preferably particulate support, comprises dividing the support into lots, performing a different chemical reaction on each lot of the support, e.g. to couple a chemical moiety to that lot of the support, tagging a fraction of each lot of the support with a different label, and combining the said lots of the support. The steps are repeated several times, preferably to build up oligomer molecules carrying labels which identify the nature and position of a monomer unit of the oligomer, and which are releasable from the support. Preferred labels, which are releasable from the compounds by cleavage to provide charged groups for analysis by mass spectrometry, are groups of the trityl (trimethylphenyl) family. Also claimed are libraries of these labels is and their use in assays and nucleic acid analysis methods.

Abstract: Nucleoside analogues or base analogues having structure (I), where X=O or NH or S, Y=N or CHR6 or CR6, W=N or NR6 or CHR6 or CR6 or S, n=1 or 2; each R6 is independently H or O or alkyl or alkenyl or alkoxy or aryl or a reporter moiety; where necessary (i.e. when Y and/or W is N or CR6 where R6 is not O) a double bond is present between Y and W or W and W, and Q is H or a sugar or a sugar analogue or a nucleic acid backbone or backbone analogue.

Abstract: Nucleoside analogues have structure (2) wherein Q is H or a sugar moiety or sugar analogue or a modified sugar or a nucleic backbone or backbone analogue, W is an alkylene or alkenylene chain of 0-5 carbon atoms, any of which may carry a substituent R8, X is O or N or NR12 or CR10, X′ is O or S or N, provided that when X′ is O or S, then X is C, Y is CH or N, R6 is NH2 or SMe or SO2Me or NHNH2, each of R7 and R8 is independently H or F or alkyl or alkenyl or aryl or acyl or a reporter moiety, R12 is independently H or alkyl or alkenyl or aryl or acyl or a reporter moiety, and R10 is H or ═O or F or alkyl or aryl or a reporter moiety.

Abstract: Nucleoside analogues or base analogues having structure (1), where X=O or NH or S, Y=N or CHR6 or CR6, W=N or NR6 or CHR6 or CR6 or S, n=1 or 2; each R6 is independently H or O or alkyl or alkenyl or alkoxy or aryl or a reporter moiety; where necessary (i.e. when Y and/or W is N or CR6 where R6 is not O) a double bond is present between Y and W or W and W, and Q is H or a sugar or a sugar analogue or a nucleic acid backbone or backbone analogue.

Abstract: A wireless network having a radio frequency access point and a plurality of isochronous devices wirelessly connected to the radio frequency access point. Each of the isochronous devices receives information from the radio frequency access point including isochronous device identification data and transmission timing data. A microprocessor is connected to the radio frequency transceiver and creates a transmission time-ordered list of the plurality of isochronous devices from the isochronous device identification data and the transmission timing data. A timer provides a timed reference for each isochronous device to transmit to the radio frequency access point according to the transmission time-ordered list. The time-ordered list prevents collision of information being transmitted to the radio frequency access point.

Abstract: Various classes of dyes are provided having acid, ester or amide groups for covalent linking to biomolecules. The dyes may be prepared by use of a compound of formula (I) where R1 comprises a linker and a carboxy including acid, salt, ester including N-hydroxysuccinimide, activated ester or amide group; R2, R3, R4 and R5 are H, C1-C10 alkyl or aralkyl or a group to modify solubility or electronic or spectral properties or a functional linking group: or R4-R5 and/or R2-R4 and/or R2-R3 are linked to form an extended ring system; and R6 is H or CHO or NO.

Abstract: Nucleotide or base analogues having structure (3) or (4) wherein X═O or NH or S and each R6 is independently H or alkyl or alkenyl or alkoxy or aryl or a reporter moiety.

Abstract: Nucleoside analogues containing the degenerate base analogue P and derivatives thereof are provided with reporter moieties preferably comprising signal moieties. The nucleoside analogues are useful for labeling DNA or RNA or for incorporating in oligonucleotides.

Abstract: Nucleoside analogues in which a group M replaces the natural base where M is (1) or (2) or (3), where each of X1, X2 and X3 are C or N, each of R6 and R7 is the same or different and each is H, NO2, CO, COR8, OR8, CN, O, CON(R8)2, COOR8, SO2R8, SO3R8, SR8, NHCHO, (CH2)n(R8)2, halogen, or a reporter moiety, each of R8 and R9 is H or hydrocarbyl or a reporter moiety, and n is 0-4. The analogues are substrates for polymerase and terminal transferase enzymes.

Abstract: Process for making open celled (semi-) rigid polyurethane foams using as cell opening agent a fatty acid or a fatty acid amine or a fatty acid amide or a fatty acid ester.