Abstract: A computing system is provided, including one or more processors configured to provide a social media platform configured to serve a content feed to a user. The processor is further configured to generate user content interaction information by detecting user interactions with the content feed and provide a recommendation engine that selects content items for display in the content feed based on the generated user content interaction information. The processor is further configured to receive a refresh request to refresh the recommendation engine and refresh the recommendation engine at least in part by masking or resetting the user content interaction information upon receiving the refresh request. After the refresh, the processor is further configured to generate, via the recommendation engine, post-refresh content items based on the masked or reset user content interaction information, and transmit the post-refresh content items to the user device for display in the content feed.

Abstract: Embodiments described herein generally provide for expanding cells in a cell expansion system. The cells may be grown in a bioreactor, and the cells may be activated by an activator (e.g., a soluble activator complex). Nutrient and gas exchange capabilities of a closed, automated cell expansion system may allow cells to be seeded at reduced cell seeding densities, for example. Parameters of the cell growth environment may be manipulated to load the cells into a particular position in the bioreactor for the efficient exchange of nutrients and gases. System parameters may be adjusted to shear any cell colonies that may form during the expansion phase. Metabolic concentrations may be controlled to improve cell growth and viability. Cell residence in the bioreactor may be controlled. In embodiments, the cells may include T cells. In further embodiments, the cells may include T cell subpopulations, including regulatory T cells (Tregs), for example.

Abstract: A system for tracking use of a medical device includes an electrosurgical generator, a readable module and a read module. The electrosurgical generator is configured to selectively deliver an electrosurgical energy signal to an electrosurgical delivery device connected to the electrosurgical generator. The readable module is connected to the electrosurgical delivery device and configured to uniquely identify the electrosurgical delivery device. The read module is in communication with the electrosurgical generator that identifies the read module, the read module configured to identify the readable module and further configured to determine the viability of the electrosurgical delivery device. Delivery of electrosurgical energy to the electrosurgical delivery device is enabled by the read module if the electrosurgical delivery device is a viable device.

Abstract: A system for tracking use of a medical device includes an electrosurgical generator, a readable module and a read module. The electrosurgical generator is configured to selectively deliver an electrosurgical energy signal to an electrosurgical delivery device connected to the electrosurgical generator. The readable module is connected to the electrosurgical delivery device and configured to uniquely identify the electrosurgical delivery device. The read module is in communication with the electrosurgical generator that identifies the read module, the read module configured to identify the readable module and further configured to determine the viability of the electrosurgical delivery device. Delivery of electrosurgical energy to the electrosurgical delivery device is enabled by the read module if the electrosurgical delivery device is a viable device.

Abstract: A system for tracking use of a medical device including an electrosurgical generator, a readable module and a read module. The electrosurgical generator is configured to selectively deliver an electrosurgical energy signal to an electrosurgical delivery device connected to the electrosurgical generator. The readable module is connected to the electrosurgical delivery device and configured to uniquely identify the electrosurgical delivery device. The read module is in communication with the electrosurgical generator that identifies the read module, the read module configured to identify the readable module and further configured to determine the viability of the electrosurgical delivery device. Delivery of electrosurgical energy to the electrosurgical delivery device is enabled by the read module if the electrosurgical delivery device is a viable device.

Abstract: Methods, and related products and compositions, of increasing the stability of a Bayer process liquor are described. A method of increasing the stability of a Bayer process liquor includes contacting the Bayer process liquor with a ppm quantity of a low molecular weight dextran. Also described are methods, and related products and compositions, for controlling the precipitation of aluminum-containing compounds from a Bayer process liquor.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members having a proximal end and a distal end. The jaw members are moveable relative to one another from a first spaced apart position to a second position in which the jaw members cooperate to grasp tissue. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. Each electrode may be hingedly connected to the respective jaw member to promote parallel closure of the sealing surfaces against tissue between the jaw members.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members having a proximal end and a distal end. The jaw members are moveable relative to one another from a first spaced apart position to a second position in which the jaw members cooperate to grasp tissue. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. Each electrode may be pivotably connected on a distal end to the respective jaw member to promote parallel closure of the sealing surfaces against tissue between the jaw members. Each electrode may be connected to its respective jaw member on a proximal end via a resilient member to bias the electrode against tissue disposed between the jaw members.

Abstract: Methods, and related products and compositions, of increasing the stability of a Bayer process liquor are described. A method of increasing the stability of a Bayer process liquor includes contacting the Bayer process liquor with a ppm quantity of a low molecular weight dextran. Also described are methods, and related products and compositions, for controlling the precipitation of aluminium-containing compounds from a Bayer process liquor.

Abstract: A system for tracking use of a medical device including an electrosurgical generator, a readable module and a read module. The electrosurgical generator is configured to selectively deliver an electrosurgical energy signal to an electrosurgical delivery device connected to the electrosurgical generator. The readable module is connected to the electrosurgical delivery device and configured to uniquely identify the electrosurgical delivery device. The read module is in communication with the electrosurgical generator that identifies the read module, the read module configured to identify the readable module and further configured to determine the viability of the electrosurgical delivery device. Delivery of electrosurgical energy to the electrosurgical delivery device is enabled by the read module if the electrosurgical delivery device is a viable device.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. A pivot mechanism is operably connected to the jaw members and configured to allow selective movement of the jaw members relative to one another from a first spaced apart position to a second position. The pivot mechanism is configured to promote substantially parallel movement of the jaw members through a range of motion between the first position and the second position.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. A trapezoidal pivot mechanism is operably connected to the jaw members and configured to allow selective movement of the jaw members relative to one another from a first spaced apart position to a second position. The trapezoidal pivot mechanism is configured to promote substantially parallel movement of the jaw members through a range of motion between the first position and the second position.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members having a proximal end and a distal end. The jaw members are moveable relative to one another from a first spaced apart position to a second position in which the jaw members cooperate to grasp tissue. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. Each electrode may be pivotably connected to the respective jaw member to promote parallel closure of the sealing surfaces against tissue between the jaw members. Each electrode may be wedge-shaped such that the thickness of the electrode increases distally along a length thereof to promote parallel closure of the sealing surfaces against tissue between the jaw members.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members having a proximal end and a distal end. The jaw members are moveable relative to one another from a first spaced apart position to a second position in which the jaw members cooperate to grasp tissue. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. Each electrode may be hingedly connected to the respective jaw member to promote parallel closure of the sealing surfaces against tissue between the jaw members.

Abstract: A bipolar forceps for sealing tissue includes an end effector assembly having opposing first and second jaw members having a proximal end and a distal end. The jaw members are moveable relative to one another from a first spaced apart position to a second position in which the jaw members cooperate to grasp tissue. Each of the jaw members includes an electrode having an electrically conductive tissue sealing surface. An electrical energy source may be connected to the tissue sealing surfaces so that the sealing surfaces can conduct energy to tissue. Each electrode may be pivotably connected on a distal end to the respective jaw member to promote parallel closure of the sealing surfaces against tissue between the jaw members. Each electrode may be connected to its respective jaw member on a proximal end via a resilient member to bias the electrode against tissue disposed between the jaw members.

Abstract: An oversampling pulse oximeter includes an analog to digital converter with a sampling rate sufficient to take multiple samples per source cycle. In one embodiment, a pulse oximeter (100) includes two or more light sources (102) driven by light source drives (104) in response to drive signals from a digital signal processing unit (116). The source drives (104) may drive the sources (102) to produce a frequency division multiplex signal. The optical signals transmitted by the light sources (102) are transmitted through a patient's appendage (103) and impinge on a detector (106). The detector (106) provides an analog current signal representative of the received optical signals. An amplifier circuit (110) converts the analog current signal to an analog voltage signal in addition to performing a number of other functions. The amplifier circuit (110) outputs an analog voltage signal which is representative of the optical signals from the sources (102).

Abstract: A system and method of reducing cross talk in pulse oximetry signals that are attenuated by a patient tissue site are provided. In one embodiment, Red and IR LEDs of a pulse oximeter are separately excited (1010) and the respective Red and IR data vectors output by the detector are measured (1020). The Red and IR data vectors are normalized (1030). Red to IR and IR to Red cross talk vectors are computed (1040). Red and IR demodulation vectors are obtained by subtracting (1050) the respective Red and IR cross talk vectors from the respective normalized Red and IR data vectors. The demodulation vectors are normalized (1060), scaled (1070), and the magnitudes of the Red and IR signal components are obtained by computing (1080) the dot product of the composite signal data vector with the normalized and scaled Red demodulation and IR demodulation vectors, respectively.

Abstract: An oversampling pulse oximeter includes an analog to digital converter with a sampling rate sufficient to take multiple samples per source cycle. In one embodiment, a pulse oximeter (100) includes two mor more light sources (102) driven by light source drives (104) in response to drive signals from a digital signal processing unit (116). The source drives (104) may drive the sources (102) to produce a frequency division multiplex signal. The optical signals transmitted by the light sources (102) are transmitted through a patient's appendage (103) and impinge on a detector (106). The detector (106) provides an analog current signal representative of the received optical signals. An amplifier circuit (110) converts the analog current signal to an analog voltage signal in addition to performing a number of other functions. The amplifier circuit (110) outputs an analog voltage signal which is representative of the optical signals from the sources (102).

Abstract: The present invention provides a reduced wire count voltage-drop sense system and method wherein the voltage drop across a load device is determinable using only one sense lead regardless of the number of load devices. In one embodiment, the voltage drop across any one of four LEDs (220A-D) in a photoplethysmographic probe when a drive current is applied therethrough via one of four input drive leads (230A-D) connected to separate LED terminals (222A-D) is determinable from a first voltage drop and a second voltage drop, for example, by subtracting the second voltage drop, or a portion thereof, from the first voltage drop. The first voltage drop is measurable across a terminal (232A-D) of the input drive lead (230A-D) connected to the LED (220A-D) across which the voltage drop is to be determined and a terminal (252) of a sense lead (250) connected to a common LED terminal (224).

Abstract: The present invention provides a plethysmographic signal processing method and system that achieves improved S/N ratios leading to improved patient heart rate estimates and improved plethysmographic waveform displays. The plethysmographic signal processing method and system of the present invention may be implemented using analog and/or digital components within a pulse oximeter. In one embodiment, first and second plethysmographic signals S1, S2 associated with first and second wavelengths, respectively (e.g., infrared and red), are received on first and second channels 210, 212. First and second multipliers 214, 216 multiply the first and second plethysmographic signals S1, S2 by first and second multiplication factors T1, T2. A summer 218 sums the products from the first and second multipliers 214, 216 to output a composite plethysmographic signal C on an output channel 220. The composite plethysmographic signal C may then be displayed and/or utilized to make heart rate determinations and the like.