Patents by Inventor Alan Hardwick
Alan Hardwick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8951942Abstract: A method for the preparation of carbon nanotube modified fluids such, that the dispersion of nanotubes in such fluids, exampled by those which are oil based is enhanced through the combined use of mechanical, sonic and ultrasonic devices.Type: GrantFiled: June 19, 2009Date of Patent: February 10, 2015Inventors: Martin Pick, Krzysztof Kazimiers Koziol, Alan Hardwick Windle
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Publication number: 20130028830Abstract: A method of increasing the density of carbon nanotube fibres or films containing carbon nanotubes to at least 50% w/w, said method including the steps of exposing the fibre or film to suitable density enhancing agent.Type: ApplicationFiled: September 5, 2012Publication date: January 31, 2013Inventors: Martin Pick, Alan Hardwick Windle, Jose Vilatela Garcia, Krzysztof Kazimiers Koziol
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Publication number: 20110224113Abstract: A method for the preparation of carbon nanotube modified fluids such, that the dispersion of nanotubes in such fluids, exampled by those which are oil based is enhanced through the combined use of mechanical, sonic and ultrasonic devices.Type: ApplicationFiled: June 19, 2009Publication date: September 15, 2011Inventors: Martin Pick, Krzysztof Kazimiers Koziol, Alan Hardwick Windle
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Publication number: 20100276633Abstract: A method of increasing the density of carbon nanotube fibres or films containing carbon nanotubes to at least 50% w/w, said method including the steps of exposing the fibre or film to suitable density enhancing agent, or to electromagnetic radiation, or by applying heat, or by mechanical compaction.Type: ApplicationFiled: April 28, 2008Publication date: November 4, 2010Inventors: Martin Pick, Alan Hardwick Windle, Jose Vilatela Garcia, Krzysztof Kazimiers Koziol
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Patent number: 7572631Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: GrantFiled: March 2, 2005Date of Patent: August 11, 2009Assignee: Invitrogen CorporationInventors: Ronald J Berenson, Che Law, Mark Bonyhadi, Zahbea Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Singh Chana
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Patent number: 7541184Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: GrantFiled: January 20, 2004Date of Patent: June 2, 2009Assignee: Invitrogen CorporationInventors: Ronald J. Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Singh Chana
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Publication number: 20060121005Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: March 2, 2005Publication date: June 8, 2006Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Zahbea Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Chana
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Publication number: 20050214942Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: November 8, 2004Publication date: September 29, 2005Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Chana
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Publication number: 20050153447Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: December 2, 2004Publication date: July 14, 2005Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Chana
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Patent number: 6905874Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: GrantFiled: February 26, 2001Date of Patent: June 14, 2005Assignee: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Patent number: 6867041Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and/or stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: GrantFiled: April 26, 2002Date of Patent: March 15, 2005Assignee: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Publication number: 20040241162Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: January 20, 2004Publication date: December 2, 2004Applicant: XCYTE Therapies, Inc.Inventors: Ronald J. Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Singh Chana
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Patent number: 6797514Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: GrantFiled: September 20, 2001Date of Patent: September 28, 2004Assignee: Xcyte Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Publication number: 20030235908Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: January 22, 2003Publication date: December 25, 2003Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Singh Chana
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Publication number: 20030124122Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and/or stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: ApplicationFiled: April 26, 2002Publication date: July 3, 2003Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Publication number: 20030119185Abstract: The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.Type: ApplicationFiled: June 28, 2002Publication date: June 26, 2003Applicant: XCYTE Therapies, Inc.Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen, Harjinder Singh Chana
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Publication number: 20020119568Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: ApplicationFiled: September 20, 2001Publication date: August 29, 2002Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Publication number: 20020058019Abstract: The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement.Type: ApplicationFiled: February 26, 2001Publication date: May 16, 2002Inventors: Ronald Berenson, Che Law, Mark Bonyhadi, Narinder Saund, Stewart Craig, Alan Hardwick, Dale Kalamasz, David McMillen
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Patent number: 5536475Abstract: An apparatus for magnetic cell separation using paramagnetic microbeads includes a base upon which is movably carried a rocker member. The rocker member carries both a primary processing container in which a mixture of liquid with cells and paramagnetic microbeads is received; and a primary magnet movable from a first position adjacent to the primary container to magnetically capture the microbeads, and a second position spaced from the primary container to magnetically release the microbeads. The mixture of liquid with cells and microbeads is agitated by tilting motions of the rocker assembly, thereby achieving the binding of target cells to microbeads. The paramagnetic microbeads, with bound target cells, are captured and released by movements of the primary magnet between its first and second positions. A secondary magnet is placed downstream from the primary magnet to capture any paramagnetic microbeads which might escape from the primary magnet.Type: GrantFiled: March 14, 1994Date of Patent: July 16, 1996Assignee: Baxter International Inc.Inventors: Ahmad-Maher Moubayed, R. Alan Hardwick
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Patent number: 5336760Abstract: The invention provides an apparatus and method for the preparation of a pharmaceutical composition comprising a complex of an antigen component and the corresponding antibody component in a pharmacologically acceptable carrier. The apparatus comprises a housing chamber for containing paramagnetic particles and a platform against which the housing chamber is releasably retained. The platform contains one or more magnets located adjacent to the housing chamber when the housing chamber is positioned on the platform. The platform is secured to a support which allows the platform, and thus the housing chamber, to be rotated between a vertical and a horizontal position.Type: GrantFiled: March 12, 1992Date of Patent: August 9, 1994Assignee: Baxter International Inc.Inventors: R. Alan Hardwick, Alan K. Smith, William C. Lake, Dennis E. Chenoweth