Patents by Inventor Alan J. Schafer

Alan J. Schafer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20010056582
    Abstract: The invention provides a collection of paired samples from a plurality of mutagenized animals, wherein each paired sample comprises: a first sample comprising genetic screening material of an animal; and a second sample comprising reproductive material of that same animal. A sample of reproductive material according to the invention can be used to generate a progeny animal carrying that same mutation. The invention also provides a collection of pairs of mutant genomes, comprising a plurality of animals carrying induced mutations and a corresponding plurality of sample genomic material, wherein a pair of mutated genomes of the collection comprises an animal having a genome containing an induced mutation and the animal's sample genomic material. The mutant animal, which might need to be bred to homozygosity, is useful for investigating the function of the gene. It might also be a useful animal model for studying human disease.
    Type: Application
    Filed: July 1, 1998
    Publication date: December 27, 2001
    Inventors: MARK BODMER, JAMIE WILLIAM FOSTER, ANDREW SANDHAM, ALAN J. SCHAFER
  • Patent number: 6033861
    Abstract: In order to facilitate the screening of an organism, or a population of organisms, carrying heterozygous mutations for identifying the presence of a mutation in a gene of interest, a method is provided which utilizes mismatch binding proteins, such as MutS. The method comprises the steps of denaturing double stranded nucleic acid present in a nucleic acid sample from an organism; allowing the nucleic acid to anneal; and removing homoduplexes from the annealed sample, thereby retaining heteroduplexes in the sample. A positive signal from a probe specific for the gene of interest indicates that the organism carries a mutation in the gene.
    Type: Grant
    Filed: November 18, 1998
    Date of Patent: March 7, 2000
    Assignee: Incyte Genetics, Inc.
    Inventors: Alan J. Schafer, Jamie W. Foster