Patents by Inventor Alan Kugler

Alan Kugler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising amphotericin B, mehods and systems
    Patent number: 8513204
    Abstract: The present invention comprises compositions and formulations comprising amphotericin B, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
    Type: Grant
    Filed: September 20, 2006
    Date of Patent: August 20, 2013
    Assignee: Novartis AG
    Inventors: Richard Malcolmson, Alan Kugler, Theresa D. Sweeney, Keith Washco, Danforth Miller
  • Compositions comprising amphotericin B, methods, and systems
    Publication number: 20070123477
    Abstract: The present invention comprises compositions and formulations comprising amphotericin B, compositions and formulations comprising amphotericin B with one or more excipients, methods of making amphotericin B compositions and formulations, as well as systems for using amphotericin B compositions and formulations. Also provided are pharmaceutical compositions comprising the formulation, methods of administering the pharmaceutical compositions and methods of treating patients with the pharmaceutical compositions.
    Type: Application
    Filed: September 20, 2006
    Publication date: May 31, 2007
    Inventors: Richard Malcolmson, Alan Kugler, Theresa Sweeney, Keith Washco, Danforth Miller
  • Stable non-crystalline formulation comprising losartan
    Publication number: 20060160871
    Abstract: One or more embodiments of the invention provide various novel formulations, and tablet dosage forms, comprising losartan that are non-crystalline, stable, and/or otherwise improvements over known losartan formulations. One or more embodiments of the invention further provide methods for preparing the formulation, methods for preparing the tablet dosage form, and to methods of administering the tablet dosage and/or formulation comprising losartan. The losartan-containing formulations may be administered to a user to treat hypertension, and related conditions.
    Type: Application
    Filed: December 6, 2005
    Publication date: July 20, 2006
    Applicant: Nektar Therapeutics
    Inventors: Srinivas Palakodaty, Jiang Zhang, Andreas Kordikowski, Linda Daintree, Sarma Duddu, Alan Kugler, Herm Snyder, David Lechuga-Ballesteros, Nagesh Palepu, Michael Eldon
  • Compositions comprising amphotericin B, methods, and systems
    Publication number: 20060025355
    Abstract: A composition includes particles including at least about 95 wt % of amphotericin B, wherein the particles have a mass median diameter ranging from about 1.1 ?m to about 1.9 ?m. Another composition also includes particles including at least about 95 wt % of amphotericin B, wherein at least about 80 wt % of the particles have a geometric diameter ranging from about 1.1 ?m to about 1.9 ?m. Yet another composition includes particles including amphotericin B, wherein the particles have a mass median diameter less than about 1.9 ?m, and wherein the amphotericin B has a crystallinity level of at least about 20%. Unit dosage forms, delivery systems, and methods may involve similar compositions.
    Type: Application
    Filed: June 21, 2005
    Publication date: February 2, 2006
    Applicant: Nektar Therapeutics
    Inventors: Sarma Duddu, Srinivas Palakodaty, David Lechuga-Ballesteros, Danforth Miller, Alan Kugler, Christopher Frantz, Trixie Tan, Richard Malcomson, Keith Washco, Theresa Sweeney, Thomas Tarara, Sarvajna Dwivedi, Michael Eldon