Patents by Inventor Alan M. Laibelman

Alan M. Laibelman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Platelet ADP receptor inhibitors
    Patent number: 6667306
    Abstract: The invention relates to novel compounds of formula (I) containing fused heterocyclic ring systems which are effective platelet ADP receptor inhibitors: In formula (I), W is carbon or nitrogen, wherein at least one W is a carbon; and Y is nitrogen, oxygen, or sulfur. Such compounds including pharmaceutically acceptable salts are useful in various pharmaceutical compositions for the prevention and/or treatment of cardiovascular disease particularly those related to thrombosis.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: December 23, 2003
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Alan M. Laibelman, Hans-Michael Jantzen, Pamela B. Conley, Larry J. Fretto, Robert M. Scarborough
  • Inhibitors of factor Xa
    Patent number: 6245743
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: May 15, 1998
    Date of Patent: June 12, 2001
    Assignee: COR Therapeutics, Inc.
    Inventors: Charles K. Marlowe, Robert M. Scarborough, Alan M. Laibelman, Uma Sinha, Bing-Yan Zhu
  • Inhibitors of factor XA
    Patent number: 6046169
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 4, 2000
    Assignee: COR Therapeutics, Inc.
    Inventors: Charles K. Marlowe, Robert M. Scarborough, Alan M. Laibelman, Uma Sinha, Bing-Yan Zhu
  • Inhibitors of factor XA
    Patent number: 5919765
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 6, 1999
    Assignee: COR Therapeutics, Inc.
    Inventors: Charles K. Marlowe, Robert M. Scarborough, Alan M. Laibelman, Uma Sinha, Bing-Yan Zhu
  • Pharmaceutical pyrazole compositions useful as inhibitors of protein kinases
    Patent number: 5916908
    Abstract: A method for selectively inhibiting a kinase is disclosed, which comprises contacting a composition containing a kinase with a compound of the formula: ##STR1## wherein: R.sub.1 is lower alkyl, lower hydrocarbyl, aryl lower alkyl, heteroaryl lower alkyl, 5- or 6-membered heterocyclic aromatic, polyaromatic, polyaromatic carbonyl, polyheteroaromatic or polyheteroaromatic carbonyl; R.sub.2 is lower alkyl, lower hydrocarbyl, aryl lower alkyl, heteroaryl lower alkyl, 5- or 6-membered heterocyclic aromatic, lower hydrocarboyl, 5- or 6-membered heterocyclic aromatic carbonyl, polyaromatic or polyheteroaromatic; R.sub.3 is H or lower alkyl; R.sub.5 is H, lower alkyl, lower hydrocarbyl, aryl lower alkyl, heteroaryl lower alkyl, 5- or 6-membered heterocyclic aromatic, halogen, or cyano; and R.sub.6 is H or lower hydrocarboyl.
    Type: Grant
    Filed: November 9, 1995
    Date of Patent: June 29, 1999
    Assignee: COR Therapeutics, Inc.
    Inventors: Neill A. Giese, Nathalie Lokker, Alan M. Laibelman, Robert M. Scarborough
  • Inhibitors of factor Xa
    Patent number: 5721214
    Abstract: Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 24, 1998
    Assignee: COR Therapeutics, Inc.
    Inventors: Charles K. Marlowe, Robert M. Scarborough, Alan M. Laibelman, Uma Sinha, Bing-Yan Zhu