Patents by Inventor Alan M. Williams

Alan M. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11045746
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: June 29, 2021
    Assignee: Global Life Sciences Solutions USA LLC
    Inventors: John Davis, Kyril Dambuleff, Alan M. Williams
  • Patent number: 9527010
    Abstract: A separation system comprises (i) at least two separation units, each separation unit comprising a fluid inlet and a fluid outlet, wherein the separation units are connected in series outlet to inlet to form a line of separation units, and (ii) sensing and adjustment means, provided in-line between each separation unit, for continuously monitoring and adjusting at least one environmental property parameter of fluid flowing from one separation unit to a subsequent separation unit in the line of separation units. Uses of the separation system and a method for purification of a liquid containing a desired species, using separation units and in-line adjustment of a fluid flow or flows, are also disclosed.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: December 27, 2016
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Alan M. Williams, Adam Kaletski, Lisa Stack, Daniel Go, John Krasnansky, David A. Wareheim, Bin Lin
  • Publication number: 20160228791
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Application
    Filed: March 8, 2016
    Publication date: August 11, 2016
    Inventors: John Davis, kYRIL Dambuleff, Alan M. Williams
  • Patent number: 9144754
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: September 29, 2015
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • Publication number: 20140076459
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1)stable and 2) has the desired performance characteristic.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: GE Healthcare Bio-Sciences Corp.
    Inventors: ALAN M. WILLIAMS, KYRIL DAMBULEFF, KATHRYN TAYLOR, JOHN DAVIS, ADAM KALETSKI, DANIEL GO, SCOTT R. MULLER
  • Patent number: 8607829
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: December 17, 2013
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • Patent number: 8496820
    Abstract: The present invention relates to methods and apparatus for forming an homogeneous mixture of chromatography media in a vessel. The invention also relates to methods and apparatus for transferring the homogeneous media from the vessel into a second vessel in preparation for packing a chromatography column. The invention can also be used directly to pack the column with homogeneous media.
    Type: Grant
    Filed: October 29, 2009
    Date of Patent: July 30, 2013
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Roger Nordberg, Alan M. Williams
  • Patent number: 8272776
    Abstract: The present invention relates to methods and apparatus for forming an homogeneous mixture of chromatography media in a vessel. The invention also relates to methods and apparatus for transferring the homogeneous media from the vessel into a second vessel in preparation for packing a chromatography column. The invention can also be used directly to pack the column with homogeneous media.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: September 25, 2012
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Roger Nordberg, Alan M. Williams
  • Publication number: 20110073548
    Abstract: A separation system comprises (i) at least two separation units, each separation unit comprising a fluid inlet and a fluid outlet, wherein the separation units are connected in series outlet to inlet to form a line of separation units, and (ii) sensing and adjustment means, provided in-line between each separation unit, for continuously monitoring and adjusting at least one environmental property parameter of fluid flowing from one separation unit to a subsequent separation unit in the line of separation units. Uses of the separation system and a method for purification of a liquid containing a desired species, using separation units and in-line adjustment of a fluid flow or flows, are also disclosed.
    Type: Application
    Filed: September 25, 2009
    Publication date: March 31, 2011
    Applicant: GE HEAL THCARE BIO-SCIENCES CORP.
    Inventors: ALAN M. WILLIAMS, ADAM KALETSKI, LISA STACK, DANIEL GO, JOHN KRASNANSKY, DAVID A. WAREHEIM, BIN LIN
  • Publication number: 20100313992
    Abstract: This invention provides for the fully automated, hands free, packing of chromatography columns by means of delivering a pre-calculated volume of slurry and using two different packing modalities to stop the packing when either 1) this volume has been delivered in the column, or 2) when the adapter is moved to reach a bed height corresponding to the pre-calculated volume. Thus, a chromatography column can be packed in a fully automated fashion and such a column is 1) stable and 2) has the desired performance characteristic.
    Type: Application
    Filed: January 11, 2008
    Publication date: December 16, 2010
    Inventors: Alan M. Williams, Kyril Dambuleff, Kathryn Taylor, John Davis, Adam Kaletski, Daniel Go, Scott R. Muller
  • Publication number: 20100219115
    Abstract: A container system is disclosed, where the container system includes a housing. A chromatography cartridge is disposed in the housing. A structural support in the housing is configured to retain the chromatography cartridge within the housing. The housing is configured to withstand a certain amount of pressure generated inside the chromatography cartridge. The chromatography cartridge is disposed in the housing either in horizontal or in vertical position.
    Type: Application
    Filed: June 18, 2008
    Publication date: September 2, 2010
    Applicant: GE HEALTHCARE BIOSCIENCES CORP.
    Inventors: John Davis, Kyril Dambuleff, Alan M. Williams
  • Publication number: 20100046322
    Abstract: The present invention relates to methods and apparatus for forming an homogeneous mixture of chromatography media in a vessel. The invention also relates to methods and apparatus for transferring the homogeneous media from the vessel into a second vessel in preparation for packing a chromatography column. The invention can also be used directly to pack the column with homogeneous media.
    Type: Application
    Filed: October 29, 2009
    Publication date: February 25, 2010
    Applicant: GE HEAL THCARE BIO-SCIENCES AB
    Inventors: ROGER NORDBERG, Alan M. Williams
  • Publication number: 20090158821
    Abstract: A device, method and system for measuring one or more ultrasound parameters of a suspension comprising particles dispersed in a liquid carrier comprising, an immersible devices, comprising, one or more ultrasonic probes; a reflector having staggered reflective; a housing having an opening into the housing to allow the suspension to flow into the space between the probe surface and the reflective surface; an ultrasound wave generator/receiver device; and a signal processing device.
    Type: Application
    Filed: December 20, 2007
    Publication date: June 25, 2009
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Zongqi Sun, Shridhar Champaknath Nath, Alan M. Williams, Baskaran Ganesan, Mottito Togo, Roger Nordberg, Matthew Allen Radebach
  • Publication number: 20080179260
    Abstract: The present invention relates to methods and apparatus for forming an homogeneous mixture of chromatography media in a vessel. The invention also relates to methods and apparatus for transferring the homogeneous media from the vessel into a second vessel in preparation for packing a chromatography column. The invention can also be used directly to pack the column with homogeneous media.
    Type: Application
    Filed: January 31, 2007
    Publication date: July 31, 2008
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: ROGER NORDBERG, ALAN M. WILLIAMS
  • Patent number: D567959
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: April 29, 2008
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Alan M. Williams, Roger Nordberg