Abstract: A computer-readable storage medium may include executable instructions stored thereon that, when executed by a processor, may be configured to establish a connection to a node of a distributed ledger network that maintains a distributed ledger. The processor may obtain a first dataset from a first user, perform pre-processing on the first dataset to obtain a first data asset based on the first dataset, and store the first data asset. The processor may calculate a first value for the first data asset and generate a first data proposition based on the first data asset. The processor may obtain acceptance data from a second user, which may include data indicating acceptance by the second user of the first data proposition. The processor may transmit a first distributed ledger record to the node of the distributed ledger network.

Abstract: A multivesicular lipid nanoparticle composition includes a plurality of multivesicular lipids. Each multivesicular lipid nanoparticle includes a carrier phospholipid micelle including a carrier phospholipid layer and having an average diameter less than 1 micron; and at least one sub-chamber phospholipid inverse micelle including a sub-chamber phospholipid layer and having an average diameter less than 100 nm. The carrier micelle nanoparticle encapsulates the at least one sub-chamber inverse micelle nanoparticle. Characteristically, phospholipid tail groups of the carrier micelle are covalently linked to the phospholipid tail groups of at least one sub-chamber inverse micelle nanoparticle.

Abstract: A rescue system for evacuating an incapacitated person from an elevated area includes a frame configured to be mounted on a pair of vertical posts extending upwardly from a surface of the elevated area, the posts defining a plane, wherein at least a portion of the frame is cantilevered out from the plane of the posts, and a lowering system supported by the cantilevered portion of the frame, the lowering system being configured to allow a rescuer to lower the incapacitated person by rope from the elevated area.

Abstract: A method includes detecting a user interaction with a particular region of a graphical user interface (GUI), and determining that the user interaction will be consumed by a particular user interface (UI) component that is overlaid by a plurality of UI components configured to allow the user interaction to pass through to the particular UI component. The method also includes, based on determining that the user interaction will be consumed by the particular UI component, determining a cumulative opacity of the plurality of UI components at the particular region of the GUI. The method further includes determining that the cumulative opacity exceeds a threshold opacity and, based on determining that the cumulative opacity exceeds the threshold opacity, blocking the particular UI component from consuming the user interaction.

Abstract: A computer-readable storage medium may include executable instructions stored thereon that, when executed by a processor, may be configured to establish a connection to a node of a distributed ledger network that maintains a distributed ledger. The processor may obtain a first dataset from a first user, perform pre-processing on the first dataset to obtain a first data asset based on the first dataset, and store the first data asset. The processor may calculate a first value for the first data asset and generate a first data proposition based on the first data asset. The processor may obtain acceptance data from a second user, which may include data indicating acceptance by the second user of the first data proposition. The processor may transmit a first distributed ledger record to the node of the distributed ledger network.

Abstract: Various embodiments of apparatuses and methods for multi-cast, multiple unicast, and unicast distribution of messages with time synchronized delivery are described. In some embodiments, the disclosed system and methods include a reference timekeeper providing a reference clock to one or more host computing devices. The one or more host computing devices host compute instances, and also contain respective isolated timing hardware outside the control of the compute instances. The isolated timing hardware of the one or more host computing devices then receive respective packets, and obtain the same time to deliver the respective packets. Each isolated timing hardware provides either the packet, or information to access the packet, to its respective destination compute instance subsequent to determining that the same specified time to deliver the packet has occurred. Thus, the respective packets are delivered near simultaneously to the one or more destination compute instances.

Abstract: Systems and methods are provided for highly accurate synchronization of machine instances in a distributed, hosted computing environment to a reference timekeeper. In addition to a general communication network accessible to machine instances, the distributed environment includes a second network dedicated to carrying time information, such as a pulse-per-second (PPS) signal to isolated timing hardware within host computing devices. The isolated timing hardware can use the PPS signal, along with a reference time, to set a hardware clock. The isolated timing hardware can further provide an interface to machine instances that enables the instances to read the time of the hardware clock. This configuration enables many instances can share access to a single reference timekeeper, thus synchronizing those instances to a much higher accuracy than in traditional network-based time protocols.

Abstract: Systems and methods are provided for highly accurate synchronization of machine instances in a distributed, hosted computing environment to a reference timekeeper. In addition to a general communication network accessible to machine instances, the distributed environment includes a second network dedicated to carrying time information, such as a pulse-per-second (PPS) signal to isolated timing hardware within host computing devices. The isolated timing hardware can use the PPS signal, along with a reference time, to set a hardware clock. The isolated timing hardware can further provide an interface to machine instances that enables the instances to read the time of the hardware clock. This configuration enables many instances can share access to a single reference timekeeper, thus synchronizing those instances to a much higher accuracy than in traditional network-based time protocols.

Abstract: A computer-readable storage medium may include executable instructions stored thereon that, when executed by a processor, may be configured to establish a connection to a node of a distributed ledger network that maintains a distributed ledger. The processor may obtain a first dataset from a first user, perform pre-processing on the first dataset to obtain a first data asset based on the first dataset, and store the first data asset. The processor may calculate a first value for the first data asset and generate a first data proposition based on the first data asset. The processor may obtain acceptance data from a second user, which may include data indicating acceptance by the second user of the first data proposition. The processor may transmit a first distributed ledger record to the node of the distributed ledger network.

Abstract: Various embodiments of apparatuses and methods for multi-cast, multiple unicast, and unicast distribution of messages with time synchronized delivery are described. In some embodiments, the disclosed system and methods include a reference timekeeper providing a reference clock to one or more host computing devices. The one or more host computing devices host compute instances, and also contain respective isolated timing hardware outside the control of the compute instances. The isolated timing hardware of the one or more host computing devices then receive respective packets, and obtain the same time to deliver the respective packets. Each isolated timing hardware provides either the packet, or information to access the packet, to its respective destination compute instance subsequent to determining that the same specified time to deliver the packet has occurred. Thus, the respective packets are delivered near simultaneously to the one or more destination compute instances.

Abstract: Various embodiments of apparatuses and methods for trusted and/or attested packet timestamping are described. In some embodiments, the disclosed system and methods include a reference timekeeper providing a reference clock to host computing devices. The host computing devices host compute instances using a first set of computing resources, and also contain isolated timing hardware utilizing a different set of computing resources. The isolated timing hardware sets a hardware clock based on a signal corresponding to the reference clock from the reference timekeeper. The isolated timing hardware then receives a packet from a particular compute instance, creates a timestamp for the packet based at least in part on the hardware clock, where the timestamp is outside the control of the compute instances, and sends the packet and the timestamp through a data network to transmit to a packet destination.

Abstract: A toy apparatus for a horse to play with when kept in a stall of a stable. The toy apparatus includes an elongated rod member, a base frame member to support the elongated rod member on the stall, and a connection system to pivotally connect the elongated rod member to the base frame member in a manner such that, when the toy apparatus is in an installation position on the stall, the elongated rod member is to project into the stall for engagement by the horse which causes the elongated rod member to pivot relative to the base frame member.

Abstract: The present invention relates to the field of food technology and in particular, nutrient and bioactive rich plant formulations. Formulated products including nutrients and bioactives such as those provided by the Moringa plant are provided. In particular, coated or encapsulated food products having a spec release behaviour and a process for their production is described. The processes described enable food material, for example Moringa, to be used to provide nutrient dense foods that are more accessible and protected against loss of nutritional value. The resulting food products therefore allow better delivery of nutritional benefits to users.

Abstract: A multivesicular liposome composition includes a plurality of multivesicular liposomes. Each multivesicular liposome includes a carrier liposome particle including carrier phospholipid bilayer and having an average diameter less than 1 micron; and at least one sub-chamber liposome nanoparticle including a sub-chamber liposome nanoparticle bilayer and having an average diameter less than about 50 nm. The carrier liposome particle encapsulates the at least one sub-chamber liposome nanoparticle. Characteristically, tail groups of the carrier liposome phospholipids are larger than tail groups phospholipids of the at least one sub-chamber liposome nanoparticle.

Abstract: A connector includes a first body, a second body, a first fastener, and a second fastener. The first body has a base portion and a protrusion, the protrusion extends away from the base portion along a first direction, and the first body has a first cavity that extends into the protrusion and towards the base portion along the first direction. The second body has a second cavity, which is shaped to receive the protrusion such that rotation of the first body relative to the second body is blocked. The connector may be used to attach structural members, for example during the construction of a modular structure.

Abstract: The present invention is directed to a cosmetic composition precursor that is rapidly hydratable and conducive to creating a personalized end-product. This invention thus relates to a cosmetic composition precursor having fatty acid, inorganic base, and high HLB surfactants and methods of using said precursors in creating the end-product. The invention also relates to end-use compositions made from the hydratable cosmetic composition precursor of the invention.

Abstract: The present invention provides processes for the preparation of sugammadex: (I) In one aspect, there is provided a process for the preparation of sugammadex from 8-per-deoxy-8-bromo-?-cyclodextrin and 3-mercaptopropionic acid. In another aspect, there is provided an alternative process for the preparation of sugammadex from 8-per-deoxy-8-bromo-?-cyclodextrin and disodium 3 -mercaptopropionate. In another aspect, there is provided a process for the preparation of 8-per-deoxy-8-bromo-?-cyclod extrin, which may be used in the production of sugammadex. In one such aspect, there is provided a process for the preparation of 8-per-deoxy-8-bromo-y-cyclodextrin from ?-cyclodextrin and a brominating agent. In another such aspect, there is provided a process for the preparation of 8-per-deoxy-8-bromo-?-cyclodextrin comprising, inter alia, reacting ?-cyclodextrin with an electrophilic brominating agent, a deoxygenating agent, and an acid in the presence of an organic solvent.

Abstract: Directional capacity of interfaces for networking devices are dynamically modified. Network traffic utilization of one direction of a network interface may be determined. A modification to a capacity of the networking device to process network traffic in the one direction of the network may be determined. The modification may then be applied to the networking device so that subsequent network traffic is processed according to the modified capacity in the one direction of the interface.

Abstract: A toy apparatus for a horse to play with when kept in a stall of a stable. The toy apparatus includes an elongated rod member, a base frame member to support the elongated rod member on the stall, and a connection system to pivotally connect the elongated rod member to the base frame member in a manner such that, when the toy apparatus is in an installation position on the stall, the elongated rod member is to project into the stall for engagement by the horse which causes the elongated rod member to pivot relative to the base frame member.

Abstract: A frozen battered fish product, method and apparatus for production. The product comprises a fried batter coating with a pre-defined pattern of ridges and troughs which create a textured batter surface. A frozen aqueous protective layer is disposed over a part of the batter coating to protect textured features including the pattern of ridges and troughs. The aqueous protective layer is designed particularly to provide protection when a more brittle frying batter is used, as a result of using a frying medium with lower saturated fat content.