Patents by Inventor Alan Millar
Alan Millar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240108844Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.Type: ApplicationFiled: September 20, 2023Publication date: April 4, 2024Inventors: Hamish Adrian OSBORNE, Gavin Walsh Millar, Stephen David Evans, Bruce Gordon Holyoake, James William Stanton, David Leon McCauley, Gareth Thomas McDermott, Nicholas James Michael McKenna, Myfanwy Jane Antica Norton, Adrian John Elsworth, Michael John Andresen, Jonathan Andrew George Lambert, Sandeep Singh Gurm, Tessa Hazel Paris, Joseph Nathaniel Griffiths, Ping Si, Christopher Gareth Sims, Elmo Benson Stoks, Dexter Chi Lun Cheung, Peter Alan Seekup, Po-Yen Liu, Richard Edward Lang, Paul James Tonkin, Ian Lee Wai Kwan
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Publication number: 20240033234Abstract: The present disclosure, in part, is directed to compositions comprising a compound of formula (I): wherein the compositions are substantially free of an impurity, processes of producing thereof, and uses thereof.Type: ApplicationFiled: August 9, 2023Publication date: February 1, 2024Inventors: Imran Alibhai, Sofia de Achaval, Alan Millar
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Patent number: 10637881Abstract: In one example in accordance with the present disclosure, a method may include receiving an initial document object model (DOM) corresponding to an HTML page structure including a plurality of executable JavaScript code and simulating user interaction with an executable JavaScript code belonging to the plurality in the HTML page structure. The method may include adjusting the initial DOM based on the simulated user interaction, generating byte code corresponding to the adjust DOM and analyzing the byte code using a set of static rules.Type: GrantFiled: August 16, 2017Date of Patent: April 28, 2020Assignee: MICRO FOCUS LLCInventors: Kevin Allen Williams, Brian Charles King, Steve Alan Millar
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Patent number: 10394698Abstract: In one example in accordance with the present disclosure, a method may include receiving code corresponding to an HTML page structure including a plurality of executable JavaScript code and enumerating a branching path in the JavaScript code. The method may include determining a branch of the branching path that would not execute during normal operation of a browser executing the JavaScript code. The method may also include generating an artificial condition for the branch and executing the branch using the artificial condition.Type: GrantFiled: August 25, 2017Date of Patent: August 27, 2019Assignee: ENTIT SOFTWARE LLCInventors: Kevin Allen Williams, Steve Alan Millar, Stephen Daniel Hardeman
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Publication number: 20180074943Abstract: In one example in accordance with the present disclosure, a method may include receiving code corresponding to an HTML page structure including a plurality of executable JavaScript code and enumerating a branching path in the JavaScript code. The method may include determining a branch of the branching path that would not execute during normal operation of a browser executing the JavaScript code. The method may also include generating an artificial condition for the branch and executing the branch using the artificial condition.Type: ApplicationFiled: August 25, 2017Publication date: March 15, 2018Inventors: Kevin Allen Williams, Steve Alan Millar, Stephen Daniel Hardeman
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Publication number: 20180063180Abstract: In one example in accordance with the present disclosure, a method may include receiving an initial document object model (DOM) corresponding to an HTML page structure including a plurality of executable JavaScript code and simulating user interaction with an executable JavaScript code belonging to the plurality in the HTML page structure. The method may include adjusting the initial DOM based on the simulated user interaction, generating byte code corresponding to the adjust DOM and analyzing the byte code using a set of static rules.Type: ApplicationFiled: August 16, 2017Publication date: March 1, 2018Inventors: Kevin Allen Williams, Brian Charles King, Steve Alan Millar
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Patent number: 9653271Abstract: The present disclosure relates, in part, to MS apparatus, methods, and/or software, having improved selectivity, sensitivity, specificity, resolution, mass accuracy and dynamic range over conventional MS technologies. In particular, the technology relates to apparatus, methods, and/or software wherein a combination of in-source fragmentation, ion mobility separation, and/or time-aligned parallel (TAP) sample ion fragmentations are utilized in mass spectrometry for the analysis of samples.Type: GrantFiled: June 7, 2013Date of Patent: May 16, 2017Assignee: Waters Technologies CorporationInventors: Henry Y. Shion, Giorgis Mezengie Isaac, Alan Millar, Tim Riley
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Patent number: 9390897Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: GrantFiled: September 22, 2014Date of Patent: July 12, 2016Assignee: Micromass UK LimitedInventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb
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Patent number: 9102593Abstract: This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.Type: GrantFiled: January 16, 2012Date of Patent: August 11, 2015Assignee: Glaxo Group LimitedInventors: Russ N. Fitzgerald, Alan Millar, Jennifer Fell Toczko
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Publication number: 20150170893Abstract: The present disclosure relates, in part, to MS apparatus, methods, and/or software, having improved selectivity, sensitivity, specificity, resolution, mass accuracy and dynamic range over conventional MS technologies. In particular, the technology relates to apparatus, methods, and/or software wherein a combination of in-source fragmentation, ion mobility separation, and/or time-aligned parallel (TAP) sample ion fragmentations are utilized in mass spectrometry for the analysis of samples.Type: ApplicationFiled: June 7, 2013Publication date: June 18, 2015Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: Henry Y. Shion, Giorgis Mezengie Isaac, Alan Millar, Tim Riley
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Publication number: 20150008319Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: ApplicationFiled: September 22, 2014Publication date: January 8, 2015Inventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb
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Publication number: 20140338429Abstract: The present invention provides methods of separating, profiling and analyzing molecular species contained within a biological sample using a high purity chromatographic material (HPCM) comprising a chromatographic surface wherein the chromatographic surface comprises a hydrophobic surface group and one or more ionizable modifiers with the proviso that when the ionizable modifier does not contain a Zwitterion, the ionizable modifier does not contain a quaternary ammonium ion moiety.Type: ApplicationFiled: May 31, 2012Publication date: November 20, 2014Applicant: Waters Technologies CorporationInventors: Giorgis Isaac, Stephen McDonald, Alan Millar, Kenneth Fountain, John Shockcor
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Patent number: 8841606Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: GrantFiled: October 5, 2011Date of Patent: September 23, 2014Assignee: Micromass UK LimitedInventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb
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Publication number: 20130345465Abstract: This invention relates to a novel chemical process for the synthesis of 2-ethyoxycarbonylamino-5-(4-fluorobenzylamino)-nitrobenzene and its use in the preparation of 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene (retigabine/ezogabine) and its polymorphic forms thereof.Type: ApplicationFiled: January 16, 2012Publication date: December 26, 2013Applicant: GLAXO GROUP LIMITEDInventors: Russ N. Fitzgerald, Alan Millar, Jennifer Fell Toczko
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Patent number: 8536403Abstract: The present invention provides a transgenic wheat cell or wheat plant, the wheat cell or wheat plant comprising a chimeric DNA molecule which encodes a dsRNA molecule which is capable of inhibiting wheat streak mosaic virus (WSMV) replication, wherein the wheat cell or plant is immune to WSMV. The present invention also provides a chimeric DNA, the chimeric DNA comprising (i) a wheat expressible promoter; (ii) a region which encodes a dsRNA which is capable of inhibiting WSMV replication; and (iii) a transcription termination and polyadenylation signal.Type: GrantFiled: September 17, 2010Date of Patent: September 17, 2013Assignee: Commonwealth Scientific and Industrial Research OrganisationInventors: Muhammad Fahim, Philip John Larkin, Ligia Isabel Ayala-Navarrete, Anthony Alan Millar
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Patent number: 8269082Abstract: The present invention relates to polypeptides, and polynucleotides encoding therefor, which influence seed dormancy in cereals such as wheat and barley. In particular, the present invention relates to polypeptides with ABA 8?-hydroxylase activity, and polynucleotides encoding these proteins. Also provided are cereal plants which produce seeds that have altered rates of germination, and/or levels of dormancy, when compared to seeds from wild-type plants, as well as methods of producing such plants.Type: GrantFiled: October 19, 2006Date of Patent: September 18, 2012Assignee: Commonwealth Scientific and Industrial Research OrganisationInventors: Anthony Alan Millar, John Viggo Jacobsen, Franz Jacques Marie Gubler
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Publication number: 20120112055Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: ApplicationFiled: October 5, 2011Publication date: May 10, 2012Applicant: MICROMASS UK LIMITEDInventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb
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Patent number: 8063357Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: GrantFiled: July 1, 2005Date of Patent: November 22, 2011Assignee: Micromass UK LimitedInventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb
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Publication number: 20110154534Abstract: The present invention provides a transgenic wheat cell or wheat plant, the wheat cell or wheat plant comprising a chimeric DNA molecule which encodes a dsRNA molecule which is capable of inhibiting wheat streak mosaic virus (WSMV) replication, wherein the wheat cell or plant is immune to WSMV. The present invention also provides a chimeric DNA, the chimeric DNA comprising (i) a wheat expressible promoter; (ii) a region which encodes a dsRNA which is capable of inhibiting WSMV replication; and (iii) a transcription termination and polyadenylation signal.Type: ApplicationFiled: September 17, 2010Publication date: June 23, 2011Inventors: Muhammad Fahim, Philip John Larkin, Ligia Isabel Ayala-Navarrete, Anthony Alan Millar
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Publication number: 20110095176Abstract: A method of searching for potentially unknown metabolites of pharmaceutical compounds is disclosed. The accurate mass of a pharmaceutical compound will generally be known and can be rendered in the form of an integer nominal mass or mass to charge ratio component and a decimal mass or mass to charge ratio component. Possible metabolites are searched for on the basis of having a decimal mass or mass to charge ratio component which is substantially very similar to the decimal mass or mass to charge ratio of the parent pharmaceutical compound.Type: ApplicationFiled: July 1, 2005Publication date: April 28, 2011Applicant: MICROMASS UK LIMITEDInventors: Jose M. Castro-Perez, Alan Millar, Robert S. Plumb