Patents by Inventor Alan P. Johnstone

Alan P. Johnstone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of blocking anti-TSH-receptor-antibodies in the therapy of hyperthyreoses and monoclonal antibodies for a use of this type
    Patent number: 7723489
    Abstract: Use of blocking antibodies against the human TSH receptor (hTSH receptor) or their specifically binding fragments for the treatment of, or for preparation of drugs for the treatment of, hyperthyroidism which is attributable to stimulating autoantibodies against the hTSH receptor (Graves' disease) or overstimulation of the thyroid gland by endogenous TSH or to activating mutations of the hTSH receptor, and for the treatment of Graves' ophthalmopathy, and specific blocking monoclonal antibodies which recognize the minimum sequence FDSH corresponding to the positions 381 to 384 of the human TSH receptor.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: May 25, 2010
    Assignee: B.R.A.H.M.S. Aktiengesellschaft
    Inventors: Andreas Bergmann, Joachim Struck, Nils Gernot Morgenthaler, Alan P. Johnstone, Philip S. Shepherd