Patents by Inventor Alan P. Sloma

Alan P. Sloma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formation of and methods for the production of large bacillus thuringiensis crystals with increased pesticidal activity
    Patent number: 6303382
    Abstract: The invention relates to a method for producing an integrant(s) of Bacillus thuringiensis which produces a larger quantity of a crystal delta-endotoxin with greater pesticidal activity as compared to the crystal delta-endotoxin produced by the corresponding parental strain. The crystal delta-endotoxin produced by the integrant Bacillus thuringiensis will have an activity directed towards the same pest(s) as its parent Bacillus thuringiensis crystal delta-endotoxin. The invention further relates to such integrants, compositions comprising such integrants, as well as methods for controlling a pest(s) using these compositions.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: October 16, 2001
    Inventors: Lee Fremont Adams, Michael David Thomas, Alan P. Sloma, William R. Widner
  • Formation of and methods for the production of large Bacillus thuringiensis crystals with increased pesticidal activity
    Patent number: 6280720
    Abstract: The invention relates to a method for producing an integrant(s) of Bacillus thuringiensis which produces a larger quantity of a crystal delta-endotoxin greater pesticidal activity as compared to the crystal delta-endotoxin produced by the corresponding parental strain. The crystal delta-endotoxin produced by the integrant Bacillus thuringiensis will have an activity directed towards the same pest(s) as its parent Bacillus thuringiensis crystal delta-endotoxin. The invention further relates to such integrants, compositions comprising such integrants, as well as methods for controlling a pest(s) using these compositions.
    Type: Grant
    Filed: July 13, 1994
    Date of Patent: August 28, 2001
    Assignees: Valant BioSciences, Inc., Libertyville, Inc.
    Inventors: Lee Fremont Adams, Michael David Thomas, Alan P. Sloma, William R. Widner
  • Production of Bacillus thuringiensis integrants
    Patent number: 6280721
    Abstract: The invention relates to a method for producing an integrant(s) of Bacillus thuringiensis. The invention further relates to such integrants, compositions comprising such integrants, as well as methods for controlling a pest(s) using these compositions.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: August 28, 2001
    Assignee: Valent BioSciences, Inc.
    Inventors: Lee Fremont Adams, Michael David Thomas, Alan P. Sloma, William R. Widner, Steen Troels Jørgensen, Per Linå Jørgensen, Børge Krag Diderichsen
  • Production of Bacillus thuringiensis integrants
    Patent number: 6270760
    Abstract: The invention relates to a method for producing an integrant(s) of Bacillus thuringiensis. The invention further relates to such integrants, compositions comprising such integrants, as well as methods for controlling a pest(s) using these compositions.
    Type: Grant
    Filed: June 10, 1997
    Date of Patent: August 7, 2001
    Assignee: Valent BioSciences, Inc.
    Inventors: Lee Fremont Adams, Michael David Thomas, Alan P. Sloma, William R. Widner, Steen Troels Jørgensen, Per Linå Jørgensen, Børge Krag Diderichsen
  • Production of bacillus thuringiensis integrants
    Patent number: 5955367
    Abstract: The invention relates to a method for producing an integrant(s) of Bacillus thuringiensis. The invention further relates to such integrants, compositions comprising such integrants, as well as methods for controlling a pest(s) using these compositions.
    Type: Grant
    Filed: April 14, 1998
    Date of Patent: September 21, 1999
    Assignee: Abbott Laboratories
    Inventors: Lee Fremont Adams, Michael David Thomas, Alan P. Sloma, William R. Widner, Steen Troels J.o slashed.rgensen, Per Lin.ang. J.o slashed.rgensen, B.o slashed.rge Krag Diderichsen
  • Bacterial donor cell useful in conjugation
    Patent number: 5763187
    Abstract: The present invention relates to a modified bacterial donor cell useful in conjugation, the cell containing i) a plasmid comprising a DNA construct encoding the polypeptide of interest, and at least one cis-acting DNA sequence required for the transfer of said plasmid by conjugation in the presence of a trans-acting mobilizing element, and ii) at least one DNA sequence encoding said trans-acting mobilizing element, wherein the donor cell has a reduced capacity, relative to a parent cell, of producing a bactericidal agent which kills or prevents growth in a population of recipient cells.
    Type: Grant
    Filed: January 17, 1997
    Date of Patent: June 9, 1998
    Assignee: Novo Nordisk Biotech, Inc.
    Inventors: Alan P. Sloma, William R. Widner
  • Promoter element and signal peptide of a gene encoding a Bacillus alkaline protease and vectors comprising same
    Patent number: 5650326
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit Anita Aaslyng
  • Recombinant methods for the production of a bacillus alkaline protease
    Patent number: 5622850
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Method for the production of heterologous polypeptides using a promoter element and signal peptide of a bacillus gene encoding an alkaline protease
    Patent number: 5622841
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 22, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng
  • Nucleic acid constructs for the production of a Bacillus alkaline protease
    Patent number: 5621089
    Abstract: The invention is directed to an isolated nucleic acid construct(s) comprising a nucleic acid sequence encoding an alkaline protease having a molecular weight of about 34 kD and is obtainable from a strain of Bacillus sp. Group I, as well as recombinant vectors and host cells comprising such constructs. Additionally, the invention is directed to a method for obtaining the protease. The invention is also directed to promoter and signal sequences derived from said alkaline protease as well as methods of using the promoter and signal sequences in the expression of heterologous nucleic acid sequences encoding heterologous proteins in bacteria.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: April 15, 1997
    Assignees: Novo Nordisk Biotech, Inc., Novo Nordisk A/S
    Inventors: Alan P. Sloma, Helle Outtrup, Claus Dambmann, Dorrit A. Aaslyng