Patents by Inventor Alan Paul Kozikowski

Alan Paul Kozikowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Huperzine A and analogs thereof
    Patent number: 5869672
    Abstract: The present invention relates to a method for the synthesis of certain bridged fused ring pyridines. Such bridged fused ring pyridines can be converted to huperzine A and analogs of huperzine A. The present invention also covers such bridged fused ring pyridines, compounds utilized for the preparation of the bridged fused ring pyridines and analogs of huperzine A.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: February 9, 1999
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alan Paul Kozikowski, Yan Xia
  • Method for the synthesis of huperzine A and analogs thereof and compounds useful therein
    Patent number: 5663344
    Abstract: The present invention relates to a method for the synthesis of certain bridged fused ring pyridines. Such bridged fused ring pyridines can be converted to huperzine A and analogs of huperzine A. The present invention also covers such bridged fused ring pyridines, compounds utilized for the preparation of the bridged fused ring pyridines and analogs of huperzine A. The compounds are capable of inhibiting cholinesterase enzymes and, therefore, are useful as pharmaceutical agents for treatment of disorders involving cholinesterase enzymes. Examples of such disorders include myasthenia gravis, Alzheimer's dementia and the improvement of senile memory loss.
    Type: Grant
    Filed: July 22, 1994
    Date of Patent: September 2, 1997
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alan Paul Kozikowski, Yan Xia