Patents by Inventor Alan R. Giles

Alan R. Giles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for controlling bleeding
    Patent number: 4721618
    Abstract: Factor VIII:C deficiency in a hemophilic mammal may be bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic). Infusion of the phosphilipid-Factor Xa mixture into normal mammals enhances the natural clotting rate and provides a method for rapidly controlling bleeding in emergency situations.
    Type: Grant
    Filed: August 9, 1985
    Date of Patent: January 26, 1988
    Assignee: Queen's University at Kingston
    Inventors: Alan R. Giles, Kenneth G. Mann
  • Composition for controlling hemophilia in mammals
    Patent number: 4610880
    Abstract: A composition of matter for controlling Hemophilia A (Antihemophilic Factor (F. VIII:C) deficiency) in mammals is described. Factor VIII:C deficiency in the mammal is bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic).
    Type: Grant
    Filed: February 6, 1985
    Date of Patent: September 9, 1986
    Assignee: Queen's University at Kingston
    Inventors: Alan R. Giles, Kenneth G. Mann
  • Method for controlling hemophilia in mammals
    Patent number: 4536392
    Abstract: A method for controlling HemophiliaA (Antihemophilic Factor (F. VIII:C) deficiency) in mammals is described. Factor VIII:C deficiency in the mammal is bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic).
    Type: Grant
    Filed: June 27, 1983
    Date of Patent: August 20, 1985
    Assignee: Queen's University at Kingston
    Inventors: Alan R. Giles, Kenneth G. Mann