Patents by Inventor Alan R. Kimmel

Alan R. Kimmel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6074842
    Abstract: The present invention provides isolated nucleic acid sequences, i.e., polynucleotides, which encode a family of perilipin proteins. The present invention also provides isolated, substantially purified perilipin proteins which are useful as markers for differentiating true adipocytes from non-adipocyte cells which, as a result of pathophysiological conditions, assume adipocyte characteristics and become lipid-laden. The present invention further provides methods for producing a substantially purified perilipin protein and methods for detecting the presence of such perilipin proteins in a biological samples.
    Type: Grant
    Filed: December 16, 1996
    Date of Patent: June 13, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Constantine Londos, Andrew S. Greenberg, Alan R. Kimmel, John J. Egan
  • Patent number: 5585462
    Abstract: The present invention provides isolated nucleic acid sequences, i.e., polynucleotides, which encode a family of perilipin proteins. The present invention also provides isolated, substantially purified perilipin proteins which are useful as markers for differentiating true adipocytes from non-adipocyte cells which, as a result of pathophysiological conditions, assume adipocyte characteristics and become lipid-laden. The present invention further provides methods for producing a substantially purified perilipin protein and methods for detecting the presence of such perilipin proteins in a biological samples.
    Type: Grant
    Filed: October 4, 1993
    Date of Patent: December 17, 1996
    Assignee: United States of America
    Inventors: Constantine Londos, Andrew S. Greenberg, Alan R. Kimmel, John J. Egan