Patents by Inventor Alan Rapacki
Alan Rapacki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10874606Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: August 19, 2019Date of Patent: December 29, 2020Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Publication number: 20200000715Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: August 19, 2019Publication date: January 2, 2020Applicant: Mati Therapeutics Inc.Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 10383817Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: December 22, 2017Date of Patent: August 20, 2019Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Patent number: 10300014Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: October 23, 2018Date of Patent: May 28, 2019Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Cary Reich, Stephen Boyd, Hanson S. Gifford, Mark Deem, Alan Rapacki
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Publication number: 20190054018Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: October 23, 2018Publication date: February 21, 2019Applicant: Mati Therapeutics Inc.Inventors: Eugene de Juan, JR., Cary Reich, Stephen Boyd, Hanson S. Gifford, Mark Deem, Alan Rapacki
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Publication number: 20180133150Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: December 22, 2017Publication date: May 17, 2018Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 9849082Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: January 13, 2017Date of Patent: December 26, 2017Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Publication number: 20170128361Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: January 13, 2017Publication date: May 11, 2017Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Patent number: 9549852Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: September 18, 2015Date of Patent: January 24, 2017Assignee: Mati Therapeutics Inc.Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Publication number: 20160008171Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: September 18, 2015Publication date: January 14, 2016Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 9168222Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: April 29, 2014Date of Patent: October 27, 2015Assignee: Mati Therapeutics Inc.Inventors: Eugene De Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S Gifford, Mark Deem
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Publication number: 20140236293Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: April 29, 2014Publication date: August 21, 2014Applicant: Mati Therapeutics Inc.Inventors: Eugene De Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Patent number: 8747884Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: GrantFiled: July 18, 2011Date of Patent: June 10, 2014Assignee: Mati Therapeutics Inc.Inventors: Eugene De Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, Mark Deem
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Publication number: 20110276131Abstract: An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.Type: ApplicationFiled: July 18, 2011Publication date: November 10, 2011Applicant: QLT INC.Inventors: Eugene de Juan, JR., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, III, Mark Deem
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Patent number: 7998497Abstract: Implant devices, systems and methods for insertion into a punctum of a patient optionally comprises a drug core and a sheath body disposed over the drug core. The drug core includes a therapeutic agent deliverable into the eye, and the sheath defines at least one exposed surface of the drug core. The exposed surface(s) of the drug core may contact a tear or tear film fluid and release the therapeutic agent at therapeutic levels over a sustained period when the implant is implanted for use. The implant may include a retention element to retain the drug core and sheath body near the punctum, optionally comprising a shape memory alloy that can resiliently expand. An occlusive element may be attached to the retention element to at least partially occlude tear flow through the canalicular lumen.Type: GrantFiled: April 2, 2007Date of Patent: August 16, 2011Assignee: QLT Inc.Inventors: Eugene de Juan, Jr., Stephen Boyd, Cary Reich, Alan Rapacki, Hanson S. Gifford, III, Mark Deem
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Publication number: 20080072914Abstract: Methods and devices are adapted for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region.Type: ApplicationFiled: August 24, 2007Publication date: March 27, 2008Inventors: Michael Hendricksen, Antony Fields, Michael Barrett, Ronald Hundertmark, Alan Rapacki, Steve Wallace, Michael Regan, John McCutcheon
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Publication number: 20080018016Abstract: Methods and devices for manufacturing a conduit for placing a target vessel in fluid communication with a source of blood, such as a heart chamber containing blood. The conduit includes first and second portion adapted to be placed in fluid communication with a heart chamber and a target vessel. The conduit lies on the exterior of the myocardium between the blood source and the target vessel and delivers blood in multiple directions within the lumen of the target vessel. The conduit, which may be formed of any suitable synthetic vascular graft material, is generally T-shaped with the leg having two free ends disposed in the target vessel, preferably being secured thereto via a suture-free attachment. The conduit comprises vascular graft material and may be manufactured various ways, such as molding a conduit from any suitable biocompatible material or fabricating a conduit from one or more pieces of vascular graft material.Type: ApplicationFiled: September 24, 2007Publication date: January 24, 2008Inventors: Alan Rapacki, Dean Carson, A. Adam Sharkawy
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Publication number: 20070243230Abstract: Implant devices, systems and methods for insertion into a punctum of a patient optionally comprises a drug core and a sheath body disposed over the drug core. The drug core includes a therapeutic agent deliverable into the eye, and the sheath defines at least one exposed surface of the drug core. The exposed surface(s) of the drug core may contact a tear or tear film fluid and release the therapeutic agent at therapeutic levels over a sustained period when the implant is implanted for use. The implant may include a retention element to retain the drug core and sheath body near the punctum, optionally comprising a shape memory alloy that can resiliently expand. An occlusive element may be attached to the retention element to at least partially occlude tear flow through the canalicular lumen.Type: ApplicationFiled: April 2, 2007Publication date: October 18, 2007Applicant: ForSight Labs, LLCInventors: Eugene de Juan, Stephen Boyd, Cary Reich, Alan Rapacki, Hanson Gifford, Mark Deem
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Publication number: 20070233225Abstract: Devices and methods for delivering conduits into the wall of a patient's heart to communicate a coronary vessel with a heart chamber. The devices are passed through the coronary vessel and the heart wall to place the conduit and establish a blood flow path between the vessel and the heart chamber. Additional devices and methods are provided for removing tissue from a coronary vessel or the heart wall to establish a flow path between the coronary vessel in communication with the heart chamber.Type: ApplicationFiled: September 29, 2006Publication date: October 4, 2007Inventors: Alan Rapacki, Darin Gittings, Gilbert Laroya, Mark Foley
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Publication number: 20070203396Abstract: Delivery system including endoscopes are described. In an embodiment, a delivery system includes a flexible, elongate endoscope extending along a longitudinal axis when the endoscope is straightened and a first lens located on the distal region. The first lens faces a direction transverse to the longitudinal axis. The first lens permits the endoscope to provide an image of anatomical structures that offset from the axis of the endoscope.Type: ApplicationFiled: February 27, 2007Publication date: August 30, 2007Inventors: John McCutcheon, Antony Fields, Ronald Hundertmark, Michael Hendricksen, Michael Barrett, Alan Rapacki, Garrett Schwab