Patents by Inventor Alan Rudolph

Alan Rudolph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9696316
    Abstract: Disclosed are novel peptides that are useful, for example, for detecting target proteins having a ?-sheet secondary structure which may be associated with a disease, and for diagnosing and treating such a disease. Related methods and kits also are disclosed.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: July 4, 2017
    Assignee: SYSTEM OF SYSTEMS ANALYTICS, INC.
    Inventors: D. Roxanne Duan, Jonathan R. Moll, Alan Rudolph, Renee Wegrzyn
  • Publication number: 20150133632
    Abstract: Disclosed are novel peptides that are useful, for example, for detecting target proteins having a ?-sheet secondary structure which may be associated with a disease, and for diagnosing and treating such a disease. Related methods and kits also are disclosed.
    Type: Application
    Filed: June 9, 2014
    Publication date: May 14, 2015
    Applicant: Adlyfe, Inc.
    Inventors: D. Roxanne Duan, Jonathan R. Moll, Alan Rudolph, Renee Wegrzyn
  • Patent number: 8673579
    Abstract: Disclosed are agents and methods that may be used to diagnose and treat a variety of diseases associated with conformationally-altered proteins. The agents and methods may be used to identify and deliver drugs useful for treating diseases associated with conformationally-altered proteins.
    Type: Grant
    Filed: July 26, 2007
    Date of Patent: March 18, 2014
    Assignee: Adlyfe, Inc.
    Inventors: Cindy S. Orser, Alan Rudolph, Shankarrama Shivaprasad, Renee Wegrzyn
  • Publication number: 20130108549
    Abstract: Disclosed are agents and methods that may be used to diagnose and treat a variety of diseases associated with conformationally-altered proteins. The agents and methods may be used to identify and deliver drugs useful for treating diseases associated with conformationally-altered proteins.
    Type: Application
    Filed: July 5, 2011
    Publication date: May 2, 2013
    Inventors: Cindy S. Orser, Alan Rudolph, Shankarrama Shivaprasad, Renee Wegrzyn
  • Publication number: 20120282169
    Abstract: The present invention relates to the detection of traumatic brain injury by detecting A? protein aggregates associated with traumatic brain injury. These A? protein aggregates are detected using peptide and peptide mimic probes that preferentially associate with A? protein aggregates associated with traumatic brain injury.
    Type: Application
    Filed: November 4, 2010
    Publication date: November 8, 2012
    Inventors: D. Roxanne Duan, Jonathan R. Moll, Alan Rudolph
  • Publication number: 20110183311
    Abstract: The present invention provides compositions comprising freeze-dried platelets, microparticles, or both for use as a diagnostic for blood coagulation function. The invention also provides methods of diagnosing or monitoring blood coagulation function, including diagnosing or monitoring blood coagulation diseases and disorders. Kits for performing the methods of the invention are also provided.
    Type: Application
    Filed: January 27, 2010
    Publication date: July 28, 2011
    Inventors: David HO, Keith A. Moskowitz, Cindy Orser, Alan Rudolph
  • Publication number: 20100233095
    Abstract: Disclosed are novel peptides that are useful, for example, for detecting target proteins having a ?-sheet secondary structure which may be associated with a disease, and for diagnosing and treating such a disease. Related methods and kits also are disclosed.
    Type: Application
    Filed: January 28, 2010
    Publication date: September 16, 2010
    Inventors: D. Roxanne Duan, Jonathan R. Moll, Alan Rudolph, Renee Wegrzyn
  • Publication number: 20090274621
    Abstract: Described are methods for delivering a non-peptide agent across the blood-brain barrier, comprising administering to a subject a conjugate comprising (i) a non-peptide agent and (ii) pyrene, and related detection and therapeutic method.
    Type: Application
    Filed: January 30, 2009
    Publication date: November 5, 2009
    Inventors: Renee Wegrzyn, Andrew Nyborg, D. Roxanne Duan, Alan Rudolph
  • Publication number: 20090238754
    Abstract: Described are methods for delivering a peptide agent across the blood-brain barrier, comprising administering to a subject a conjugate comprising (i) a peptide agent and pyrene, and related detection and therapeutic methods.
    Type: Application
    Filed: January 30, 2009
    Publication date: September 24, 2009
    Inventors: Renee WEGRZYN, Andrew Nyborg, D. Roxanne Duan, Alan Rudolph
  • Publication number: 20080095706
    Abstract: Disclosed are agents and methods that may be used to diagnose and treat a variety of diseases associated with conformationally-altered proteins. The agents and methods may be used to identify and deliver drugs useful for treating diseases associated with conformationally-altered proteins.
    Type: Application
    Filed: July 26, 2007
    Publication date: April 24, 2008
    Inventors: Cindy Orser, Alan Rudolph, Shankarrama Shivaprasad, Renee Wegrzyn
  • Publication number: 20070243178
    Abstract: The present invention provides compositions comprising freeze-dried platelets, microparticles, or both for use as a diagnostic for blood coagulation function. The invention also provides methods of diagnosing or monitoring blood coagulation function, including diagnosing or monitoring blood coagulation diseases and disorders. Kits for performing the methods of the invention are also provided.
    Type: Application
    Filed: August 12, 2005
    Publication date: October 18, 2007
    Inventors: David Ho, Cindy Orser, Alan Rudolph, Keith Moskowitz, Joshua Dee
  • Publication number: 20060051731
    Abstract: The present invention provides processes for preparing freeze-dried platelets, freeze-dried platelets made by those processes, platelets reconstituted from those freeze-dried platelets, and kits comprising those freeze-dried platelets. The freeze-dried platelets of the invention have similar characteristics to fresh platelets, have an exceptionally long shelf-life, and can be used for all standard procedures in which fresh platelets are used, including both in vitro diagnostic and research procedures and in vivo therapies.
    Type: Application
    Filed: August 5, 2005
    Publication date: March 9, 2006
    Inventors: David Ho, Joshua Dee, Cindy Orser, Alan Rudolph
  • Publication number: 20060034809
    Abstract: The present invention provides compositions comprising freeze-dried platelets, microparticles, or both for use as a hemostat, such as for treating bleeding or injuries associated with bleeding. It also provides methods of treating injuries or wounds, and methods of causing blood to clot. Likewise, it provides methods of promoting healing of wounds or of healing wounds.
    Type: Application
    Filed: August 12, 2005
    Publication date: February 16, 2006
    Inventors: David Ho, Cindy Orser, Alan Rudolph
  • Publication number: 20060035383
    Abstract: The present invention provides compositions comprising freeze-dried platelets, microparticles, or both for use as a diagnostic for blood coagulation function. The invention also provides methods of diagnosing or monitoring blood coagulation function, including diagnosing or monitoring blood coagulation diseases and disorders. Kits for performing the methods of the invention are also provided.
    Type: Application
    Filed: June 15, 2005
    Publication date: February 16, 2006
    Inventors: David Ho, Keith Moskowitz, Cindy Orser, Alan Rudolph
  • Publication number: 20020142022
    Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.
    Type: Application
    Filed: February 19, 2002
    Publication date: October 3, 2002
    Applicant: GEO-CENTERS, INC.
    Inventors: Ronald R. Price, Joel M. Schnur, Paul E. Schoen, Mary Testoff, Jacque H. Georger, Alan Rudolph, Robert F. Brady
  • Patent number: 6422175
    Abstract: A decorative attachment for an aquarium for creating natural looking scenic features for an aquarium. The decorative attachment for an aquarium includes a wall assembly including a wall structure having a front wall and a back wall being spaced from the front wall, and also having an overhang portion being securely disposed at a top of the front and back walls and extending rearwardly thereof and being adapted to mount upon a back wall of an aquarium; and also includes a plurality of scenery attachment support members being securely attached to the wall structure; and further includes a plurality of scenery attachments being removably mounted to the wall structure.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: July 23, 2002
    Inventor: Alan Rudolph
  • Publication number: 20020083901
    Abstract: A decorative attachment for an aquarium for creating natural looking scenic features for an aquarium. The decorative attachment for an aquarium includes a wall assembly including a wall structure having a front wall and a back wall being spaced from the front wall, and also having an overhang portion being securely disposed at a top of the front and back walls and extending rearwardly thereof and being adapted to mount upon a back wall of an aquarium; and also includes a plurality of scenery attachment support members being securely attached to the wall structure; and further includes a plurality of scenery attachments being removably mounted to the wall structure.
    Type: Application
    Filed: December 29, 2000
    Publication date: July 4, 2002
    Inventor: Alan Rudolph
  • Publication number: 20010026802
    Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.
    Type: Application
    Filed: May 21, 2001
    Publication date: October 4, 2001
    Applicant: GEO-CENTERS, INC.
    Inventors: Ronald R. Price, Joel M. Schnur, Paul E. Schoen, Mary Testoff, Jacque H. Georger, Alan Rudolph, Robert F. Brady
  • Patent number: 6280759
    Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.
    Type: Grant
    Filed: March 7, 1994
    Date of Patent: August 28, 2001
    Inventors: Ronald R. Price, Joel M. Schnur, Paul E. Schoen, Mary Testoff, Jacque H. Georger, Jr., Alan Rudolph, Robert F. Brady
  • Patent number: 5492696
    Abstract: Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are useful in the production of coating compositions for the protection of surfaces coming into contact with water, adhesive resins for the production of laminated wood products, and devices for dispensing pesticides.
    Type: Grant
    Filed: June 17, 1993
    Date of Patent: February 20, 1996
    Assignees: The Government of the United States of America as represented by the Secretary of the Navy, Geo-Centers, Inc.
    Inventors: Ronald R. Price, Joel M. Schnur, Paul E. Schoen, Mary Testoff, Jacque H. Georger, Jr., Alan Rudolph, Robert F. Brady