Patents by Inventor Alan S. Harris

Alan S. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8324362
    Abstract: The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: December 4, 2012
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yan Chen, Elena Getmanova, Martin C. Wright, Alan S. Harris, Ai Ching Lim, Jochem Gokemeijer, Lin Sun, Michael Wittekind
  • Publication number: 20120283184
    Abstract: The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
    Type: Application
    Filed: July 18, 2012
    Publication date: November 8, 2012
    Applicant: Bristol-Myers Squibb Company
    Inventors: Yan Chen, Elena Getmanova, Martin C. Wright, Alan S. Harris, Ai Ching Lim, Jochem Gokemeijer, Lin Sun, Michael Wittekind
  • Patent number: 7858739
    Abstract: The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: December 28, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yan Chen, Elena Getmanova, Martin C. Wright, Alan S. Harris, Ai Ching Lim, Jochem Gokemeijer, Lin Sun, Michael Wittekind
  • Publication number: 20100310549
    Abstract: The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
    Type: Application
    Filed: May 26, 2010
    Publication date: December 9, 2010
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: YAN CHEN, ELENA GETMANOVA, MARTIN C. WRIGHT, ALAN S. HARRIS, AI CHING LIM, JOCHEM GOKEMEIJER, LIN SUN, MICHAEL WITTEKIND
  • Patent number: 7847062
    Abstract: The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.
    Type: Grant
    Filed: July 7, 2006
    Date of Patent: December 7, 2010
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yan Chen, Elena Getmanova, Martin C. Wright, Alan S. Harris, Ai Ching Lim, Jochem Gokemeijer, Lin Sun, Michael Wittekind
  • Publication number: 20080220049
    Abstract: The present disclosure relates to novel sustained-release intraocular drug delivery systems and improvements in the treatment of retinopathies. In particular, fibronectin scaffold domain proteins that selectively inhibit VEGFR-2 are contemplated.
    Type: Application
    Filed: August 17, 2007
    Publication date: September 11, 2008
    Applicant: Adnexus, A Bristol-Myers Squibb R&D Company
    Inventors: Yan Chen, Elena Getmanova, Martin C. Wright, Alan S. Harris, Ai Ching Lim, Jochem Gokemeijer, Lin Sun, Michael Wittekind
  • Publication number: 20030166521
    Abstract: The present invention relates to methods and compositions for the modulation thrombosis, in a subject, by administering a P-selectin antagonist. The invention further provides methods for modulating leukocyte recruitment, cellular migration, leukocyte rolling velocity, intercellular adhesion, and cell adhesion to blood vessels in a subject by administering soluble P-selectin ligand or fragments thereof, an anti-P-selectin ligand antibody, or an anti-P-selectin antibody. The invention also provides methods for identifying compounds capable of modulating thrombosis.
    Type: Application
    Filed: April 2, 2001
    Publication date: September 4, 2003
    Inventors: Michael J. Eppihimer, Robert G. Schaub, Alan S. Harris
  • Patent number: 4753279
    Abstract: An adjustable roller support attachment is disclosed for mounting on a clamping type work bench, available for example, under the trademark WORKMATE, for facilitate the handling of long stock in stationary power tools, the roller support attachment including a support having a yoke portion for rotatably mounting a roller and a wide, elongated base for clamping engagement by vise jaws of the work bench, a stabilizing element or collar surrounding the support base with a stabilizing surface for resting on an upper surface of the vise jaws, and a screw element or the like for releasably securing the stabilizing element to the support base in order to both stabilize the support and roller on the work bench while also facilitating height adjustment of te support attachment on the work bench for aligning the roller with a portion of the stationary power tool.
    Type: Grant
    Filed: August 7, 1987
    Date of Patent: June 28, 1988
    Inventor: Alan S. Harris