Patents by Inventor Alan Sawyer

Alan Sawyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210139607
    Abstract: Provided herein, in some embodiments, are anti-N-gly-canase 1 antibodies and methods of use.
    Type: Application
    Filed: May 22, 2019
    Publication date: May 13, 2021
    Applicant: The Jackson Laboratory
    Inventors: Alan Sawyer, Aamir Zuberi, Cathleen Marie Lutz
  • Publication number: 20090133407
    Abstract: A system is disclosed for use in producing syngas for use in a variety of commercial applications, including commercial energy generation applications. A plasma torch and cupola arrangement are used to gasify feed stock such as coal, petcoke, and/or biomass, to produce syngas and liquid waste. The syngas is directed to a cleanup train, wherein detrimental components are mechanically or chemically filtered out. The cleaned syngas is then fed into a syngas burner and used to produce heat for electricity generation for the production of electricity or to another energy producing system including synthetic natural gas, ethanol, or liquid fuel oil. In some embodiments, the syngas is fed directly to a gas turbine. The liquid waste is cooled to generate in inert solid which may then be crushed and used in a variety of construction or other applications. The disclosed system may find use in new construction as well as retrofit applications.
    Type: Application
    Filed: November 20, 2008
    Publication date: May 28, 2009
    Applicant: NRG Energy, Inc.
    Inventor: Alan Sawyer
  • Publication number: 20050181483
    Abstract: The present invention relates to methods for producing monoclonal antibodies. In particular, the invention relates to high throughput methods for producing and screening monoclonal antibodies more rapidly than conventional methods.
    Type: Application
    Filed: April 17, 2003
    Publication date: August 18, 2005
    Inventors: Alan Sawyer, Federico De Masi
  • Patent number: 6620848
    Abstract: The present invention relates to novel amidino compound of formula (I): to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.
    Type: Grant
    Filed: August 15, 2001
    Date of Patent: September 16, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Richard Mansfield Beams, Martin James Drysdale, Karl Witold Franzmann, Anthony Joseph Frend, Harold Francis Hodson, Richard Graham Knowles, Daryl David Rees, David Alan Sawyer
  • Patent number: 6369272
    Abstract: The present invention relates to novel amidino compound of formula (I). to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible nitric oxide synthase.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: April 9, 2002
    Assignee: GlaxoSmithKline
    Inventors: Richard Mansfield Beams, Martin James Drysdale, Karl Witold Franzmann, Anthony Joseph Frend, Harold Francis Hodson, Richard Graham Knowles, Daryl David Rees, David Alan Sawyer
  • Publication number: 20020010366
    Abstract: The present invention relates to novel amidino compound of formula (I).
    Type: Application
    Filed: August 15, 2001
    Publication date: January 24, 2002
    Inventors: Richard Mansfield Beams, Martin James Drysdale, Karl Witold Franzmann, Anthony Joseph Frend, Harold Francis Hodson, Richard Graham Knowles, Daryl David Rees, David Alan Sawyer
  • Patent number: 5912345
    Abstract: The invention provides a process for producing lamotrigine of formula (I): ##STR1## which process comprises subjecting a compound of formula (II): ##STR2## wherein R is CN or CONH.sub.2, in an organic solvent, to ultra violet or visible radiation and, when R is CN, to heat.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: June 15, 1999
    Assignee: Glaxo Wellcome Inc.
    Inventors: Raymond Geoffrey Winter, David Alan Sawyer, Andrew Germain
  • Patent number: 5889056
    Abstract: A compound of formula (I) ##STR1## wherein R.sup.1 is a C.sub.1-6 straight or branched chain alkyl group, a C.sub.2-6 alkenyl group, a C.sub.2-6 alkynyl group, a C.sub.3-6 cycloalkyl group or a C.sub.3-6 cycloalkylC.sub.1-6 alkyl group, each optionally substituted by one to three groups independently selected from: --CN; --NO.sub.2 ; a group --COR.sup.2 wherein R.sup.2 is hydrogen, C.sub.1-6 alkyl, --OR.sup.3 wherein R.sup.3 is hydrogen or C.sub.1-6 alkyl or NR.sup.4 R.sup.5 wherein R.sup.4 and R.sup.5 are independently selected from hydrogen or C.sub.1-6 alkyl; a group --S(O).sub.m R.sup.6 wherein m is 0, 1 or 2, R.sup.6 is hydrogen, C.sub.1-6 alkyl, hydroxy or NR.sup.7 R.sup.8 wherein R.sup.7 and R.sup.8 are independently hydrogen or C.sub.1-6 alkyl; a group PO(OR.sup.9).sub.2 wherein R.sup.9 is hydrogen or C.sub.1-6 alkyl; a group NR.sup.10 R.sup.11 wherein R.sup.10 and R.sup.11 are independently selected from hydrogen, C.sub.1-6 alkyl, --COR.sup.12 wherein R.sup.12 is hydrogen or C.sub.
    Type: Grant
    Filed: December 27, 1996
    Date of Patent: March 30, 1999
    Assignee: Glaxo Wellsome Inc.
    Inventors: Harold Francis Hodson, Richard Michael John Palmer, David Alan Sawyer, Richard Graham Knowles, Karl Witold Franzmann, Martin James Drysdale, Patricia Ifeyinwa Davies, Helen Alice Rebecca Clark, Barry George Shearer, Steven Smith
  • Patent number: RE39576
    Abstract: A compound of formula (I) wherein R1 is a C1-6 straight or branched chain alkyl group, a C2-6alkenyl group, a C2-6 alkynyl group, a C3-6cycloalkyl group or a C3-6cycloalkylC1-6alkyl group, each optionally substituted by one to three groups independently selected from: —CN; —NO2; a group —COR2 wherein R2 is hydrogen, C1-6 alkyl, —OR3 wherein R3 is hydrogen or C1-6alkyl or NR4R5 wherein R4 and R5 are independently selected from hydrogen or C1-6 alkyl; a group —S(O)mR6 wherein m is 0, 1 or 2, R6 is hydrogen, C1-6 alkyl, hydroxy or NR7R8 wherein R7 and R8 are independently hydrogen or C1-6 alkyl; a group PO(OR9)2 wherein R9 is hydrogen or C1-6 alkyl; a group NR10R11 wherein R10 and R11 are independently selected from hydrogen, C1-6 alkyl, —COR12 wherein R12 is hydrogen or C1-6 alkyl, or —S(O)m?R13 wherein m? is 0, 1 or 2 and R13 is hydrogen or C1-6 alkyl; halo; or a group —OR14 wherein R14 is hydrogen, C1-6 alkyl optionally substituted by one to three halo atoms, C6-10 aryl or —COR15 wherein R15 is hydroge
    Type: Grant
    Filed: June 14, 1995
    Date of Patent: April 17, 2007
    Assignee: Smithkline Beecham Corporation
    Inventors: Harold Francis Hodson, Richard Michael John Palmer, David Alan Sawyer, Richard Graham Knowles, Karl Witold Franzmann, Martin James Drysdale, Patricia Ifeyinwa Davies, Helen Alice Rebecca Clark, Barry George Shearer, Steven Smith