Patents by Inventor Alan Stein
Alan Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6248058Abstract: A method for treating a tracheo-esophageal fistula. The method comprises the steps of augmenting the wall forming the esophagus in the vicinity of the fistula and placing a stent over the fistula in the esophagus so as to inhibit material traveling down the esophagus from passing into the trachea. The augmenting of the wall facilitates support of the stent in the esophagus so as to enhance isolation of the fistula.Type: GrantFiled: April 5, 1999Date of Patent: June 19, 2001Assignee: Enteric Medical Technologies, Inc.Inventors: David E. Silverman, Alan Stein
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Patent number: 6238335Abstract: A method for treating gastroesophageal reflux disease in a body of a mammal is provided. At least one nonaqueous solution is introduced into the wall in the vicinity of the lower esophageal sphincter. A nonbiodegradable solid is formed from the at least one nonaqueous solution in the wall to augment the wall. An apparatus for use in the procedure is provided.Type: GrantFiled: January 15, 1999Date of Patent: May 29, 2001Assignee: Enteric Medical Technologies, Inc.Inventors: David E. Silverman, Alan Stein
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Patent number: 6234955Abstract: A method for treating a blood vessel in a wall forming a gastrointestinal tract of a body of a mammal. At least one nonaqueous solution is introduced from the gastrointestinal tract into the vessel. A nonbiodegradable solid is formed in the vessel in the vicinity of a portion of the vessel from the least one nonaqueous solution to create an occlusion in the vessel and thus terminate blood flow to the vessel distal of the occlusion.Type: GrantFiled: October 4, 1999Date of Patent: May 22, 2001Assignee: Enteric Medical Technologies, Inc.Inventors: David E. Silverman, Alan Stein
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Patent number: 6231613Abstract: Disclosed are methods for soft tissue augmentation in a mammal wherein a composition comprising a biocompatible polymer having a water equilibrium content of less than about 15% and a biocompatible solvent is delivered to the tissue of the mammal to be augmented.Type: GrantFiled: December 15, 1998Date of Patent: May 15, 2001Assignee: Enteric Medical Technologies, Inc.Inventors: Richard J. Greff, David E. Silverman, Alan Stein
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Patent number: 6214754Abstract: The present invention relates to thick film coating compositions which adhere particularly well to silicon nitride substrates and accordingly may be used in the manufacture of heater apparatus using such substrates. Such thick film coating materials comprise a borosilicate glass matrix containing an amount of a metal oxide sufficient to enable said thick film coating material to react with a silicon nitride substrate to promote adherence thereto; and desirably further contains ceramic powders and/or metal or metal-containing compound powders and/or flakes.Type: GrantFiled: September 21, 1999Date of Patent: April 10, 2001Assignee: Electro-Science Laboratories, Inc.Inventor: Michael Alan Stein
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Patent number: 6059780Abstract: An ablation apparatus includes a handpiece, an electrode extending from a handpiece distal end, a probe, a thermal sensor and an energy source. The electrode includes a distal end and a lumen, a cooling medium inlet conduit and a cooling medium exit conduit. Both conduits extend through the electrode lumen to an electrode distal end. A sidewall port, isolated from a cooling medium flowing in the inlet and outlet conduits, is formed in the electrode. The probe is at least partially positionable in the electrode lumen and configured to be advanced and retracted in and out of the sidewall aperture. The thermal sensor is supported by the probe. The electrode is coupled to an energy source.Type: GrantFiled: November 4, 1997Date of Patent: May 9, 2000Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 6053937Abstract: An ablation apparatus has an introducer including an introducer lumen, a proximal portion and a distal portion. Two or more electrodes are at least partially positionable in the introducer lumen. Each electrode is configured to be advanced from the introducer distal portion in a deployed state into a selected tissue site to define a volumetric ablation volume. A fluid delivery member is positioned on at least a portion of an exterior of one of the electrodes. The fluid delivery member is configured to be coupled to a fluid medium source. A cable is coupled to the electrodes.Type: GrantFiled: November 4, 1997Date of Patent: April 25, 2000Assignee: Rita Medical Systems, Inc.Inventors: Stuart D. Edwards, Patrick J. Burns, Edward J. Gough, Alan A. Stein
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Patent number: 6039757Abstract: A fenestrated stent formed in a body lumen is provided which includes an article shaped to provide support to a section of a body lumen and allow biological material which would otherwise flow through the body lumen to flow through the article, the article being formed with fenestrations bydelivering a fluent pre-stent composition to a mold space defined by a section of a body lumen and a fluent pre-stent composition delivery device having members which define the fenestrations, andtransforming the fluent pre-stent composition to a non-fluent stent composition within the mold space.Type: GrantFiled: December 1, 1997Date of Patent: March 21, 2000Assignee: CardioSynopsis, Inc.Inventors: Stuart D. Edwards, Thomas C. Wehman, Theodore L. Parker, Theodore Kucklick, Eugene V. Skalnyi, Alan Stein
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Patent number: 5951547Abstract: An ablation treatment apparatus includes an energy source. A multiple antenna device is included and has a primary antenna with a longitudinal axis, a central lumen and a distal end, and a secondary antenna with a distal end. The secondary antenna is positionable in the primary antenna after the primary antenna is positioned at a tissue site and deployed from the primary antenna central lumen in a lateral direction relative to the longitudinal axis. A selected primary or secondary antenna is electromagnetically coupled to the energy source. A non-selected antenna is electromagnetically coupled to the selected antenna. A cable connects the energy source to the selected antenna.Type: GrantFiled: November 3, 1997Date of Patent: September 14, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5928229Abstract: An ablation apparatus has a multiple antenna device with a primary antenna and a secondary antenna positionable in a lumen of the primary antenna. The secondary antenna is at least partially deployable from the primary antenna in a lateral direction relative to a longitudinal axis of the primary antenna with at least one radius of curvature. A distal end of the primary antenna is sufficiently sharp to pierce tissue. The primary and secondary antennas are configured to provide a selectable geometric ablation of a selected tissue mass. An insulation sleeve is positioned on an exterior of the primary antenna. One or more cables are coupled to the multiple antenna device.Type: GrantFiled: October 30, 1997Date of Patent: July 27, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5925042Abstract: An ablation treatment apparatus has a multiple antenna device. The multiple antenna device includes a primary antenna with a lumen, a longitudinal axis and an ablative surface area of length L.sub.1. The multiple antenna device also includes a secondary antenna that is positionable in the primary antenna. A secondary antenna distal end is deployed at a selected tissue site from the primary antenna lumen in a lateral direction relative to the longitudinal axis. A sensor is at least partially positioned at an exterior of the secondary antenna distal end at a distance L.sub.2 from the primary antenna along the secondary antenna distal end. L.sub.2 is at least equal to 1/3 L.sub.1. An energy source is coupled to the primary antenna.Type: GrantFiled: November 3, 1997Date of Patent: July 20, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5913855Abstract: An ablation treatment apparatus has a multiple antenna device. The multiple antenna device includes a primary antenna with a lumen and a longitudinal axis, and a secondary antenna positionable in the lumen. At a selected tissue site the secondary antenna is deployed in a lateral direction relative to the longitudinal axis of the primary antenna. At least a portion of a distal end of the secondary antenna is structurally less rigid than the primary antenna. The primary antenna is constructed to be rigid enough to be introduced through tissue. A cable couples one or both of the antennas to an energy source.Type: GrantFiled: November 3, 1997Date of Patent: June 22, 1999Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5899917Abstract: A method is provided for forming a stent within a body lumen. According to the method, a distal catheter body is advanced within a body lumen to a section of a body lumen at which a stent is to be formed. One or more expandable members attached to the distal catheter body are expanded such that sections of the body lumen proximal and distal to the stent formation section of the body lumen are occluded, the distal catheter body in combination with the body lumen defining a mold space. A fluent pre-stent composition is delivered to the mold space from outside the body lumen which is continuously in fluent state during pre-stent composition delivery from outside the body lumen to the mold space. The fluent pre-stent composition is then transformed within the mold space to a non-fluent stent composition to form a stent within the mold space.Type: GrantFiled: December 1, 1997Date of Patent: May 4, 1999Assignee: CardioSynopsis, Inc.Inventors: Stuart D. Edwards, Thomas C. Wehman, Theodore L. Parker, Theodore Kucklick, Peter Park, Alan Stein, Eugene V. Skalnyi
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Patent number: 5863290Abstract: An ablation treatment apparatus includes an energy source. A multiple antenna device is included and has a primary antenna with a longitudinal axis, a central lumen and a distal end, and a secondary antenna with a distal end. The secondary antenna is deployed from the primary antenna central lumen in a lateral direction to the longitudinal axis. A selected primary or secondary antenna is electromagnetically coupled to the energy source. A non-selected antenna is electromagnetically coupled to the selected antenna. A cable connects the energy source to the selected antenna.Type: GrantFiled: December 19, 1995Date of Patent: January 26, 1999Assignee: Rita Medical SystemsInventors: Edward J. Gough, Alan A. Stein
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Patent number: 5810804Abstract: An ablation apparatus includes a handpiece, an electrode extending from a handpiece distal end, a probe, a thermal sensor and an energy source. The electrode includes a distal end and a lumen, a cooling medium inlet conduit and a cooling medium exit conduit. Both conduits extend through the electrode lumen to an electrode distal end. A sidewall port, isolated from a cooling medium flowing in the inlet and outlet conduits, is formed in the electrode. The probe is at least partially positioned in the electrode lumen and configured to be advanced and retracted in and out of the sidewall aperture. The thermal sensor is supported by the probe. The electrode is coupled to an energy source.Type: GrantFiled: March 15, 1996Date of Patent: September 22, 1998Assignee: Rita Medical SystemsInventors: Edward J Gough, Alan A. Stein
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Patent number: 5800484Abstract: An ablation apparatus has an introducer including an introducer lumen, a proximal portion and a distal portion. A handpiece with a proximal portion and a distal portion is coupled to the introducer proximal portion. Two or more electrodes are at least partially positioned in the introducer lumen. Each electrode is configured to be advanced from the introducer distal portion in a deployed state into a selected tissue site to define a volumetric ablation volume. A fluid delivery member is positioned on at least a portion of an exterior of one of the electrodes. The fluid delivery member is configured to be coupled to a fluid medium source. A cable is coupled to the electrodes.Type: GrantFiled: September 3, 1996Date of Patent: September 1, 1998Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein, Stuart D. Edwards, Patrick J. Burns
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Patent number: 5782827Abstract: An ablation apparatus includes an energy source producing an ablation energy output. A multiple antenna device is included and has a primary antenna with a longitudinal axis, a central lumen and a distal end, and a first secondary antenna with a distal end. The first secondary antenna is deployed from the primary antenna central lumen in a lateral direction to the longitudinal axis. The primary antenna is coupled to the energy source to receive the ablation energy output, and the first secondary antenna is coupled to the primary antenna to receive ablation energy from the primary antenna. A sensor is positioned at one or both of the primary or secondary antennas. A feedback control system is coupled to the energy source and the sensor. The feedback control system is responsive to a detected characteristic from the sensor to provide a delivery of ablation energy output from the energy source to the antennas.Type: GrantFiled: December 19, 1995Date of Patent: July 21, 1998Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5735847Abstract: An ablation apparatus includes a multiple antenna device coupled to an electromagnetic energy source that produces an electromagnetic energy ablation output. The multiple antenna device includes a primary antenna with a lumen and a longitudinal axis, and a secondary antenna deployable from the lumen in a lateral direction relative to the longitudinal axis. At least a distal end of each secondary antenna is structurally less rigid than the primary antenna, and the primary antenna is sufficiently rigid to be introduced through tissue. At least one cable coupling the multiple antenna device to the energy source. A cooling element is coupled to the primary antenna. A variety of energy sources can be used including RF, microwave and laser.Type: GrantFiled: December 19, 1995Date of Patent: April 7, 1998Assignee: ZoMed International, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5728143Abstract: A multiple antenna ablation apparatus includes an electromagnetic energy source, a trocar including a distal end, and a hollow lumen extending along a longitudinal axis of the trocar, and a multiple antenna ablation device with three or more antennas. The antennas are initially positioned in the trocar lumen as the trocar is introduced through tissue. At a selected tissue site the antennas are deployable from the trocar lumen in a lateral direction relative to the longitudinal axis. Each of the deployed antennas has an electromagnetic energy delivery surface of sufficient size to, (i) create a volumetric ablation between the deployed antennas, and (ii) the volumetric ablation is achieved without impeding out any of the deployed antennas when 10 to 50 watts of electromagnetic energy is delivered from the electromagnetic energy source to the multiple antenna ablation device. At least one cable couples the multiple antenna ablation device to the electromagnetic energy source.Type: GrantFiled: February 14, 1996Date of Patent: March 17, 1998Assignee: Rita Medical Systems, Inc.Inventors: Edward J. Gough, Alan A. Stein
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Patent number: 5683384Abstract: An ablation apparatus has a multiple antenna device of adjustable length including an adjustable length primary antenna and an adjustable length secondary antenna. The primary antenna has a longitudinal axis, and the secondary antenna is deployed in a direction lateral to the longitudinal axis. The secondary antenna is constructed to be structurally less rigid than the primary antenna. The adjustable lengths of the primary and secondary antennas permits a desired geometric ablation of a selected tissue mass. An adjustable insulation sleeve is positioned on an exterior of one of the primary or secondary antennas. An energy source is connected to the multiple antenna device. A variety of energy sources can be used including RF, microwave and laser.Type: GrantFiled: August 15, 1995Date of Patent: November 4, 1997Assignee: ZomedInventors: Edward J. Gough, Alan A. Stein, Stuart D. Edwards