Patents by Inventor Alan Stephenson

Alan Stephenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulators of Pulmonary Hypertension
    Publication number: 20080095711
    Abstract: Compounds, compositions, and methods for inhibiting pulmonary hypertension are disclosed. The invention is particularly directed to the use of agents that specifically inhibit the activity of certain endogenously produced epoxyeicosatrienoic acids that promote vasoconstriction of pulmonary arteries. These agents are particularly useful for inhibiting hypoxia-induced pulmonary hypertension. The invention further discloses additional compounds, compositions and methods for increasing pulmonary hypertension.
    Type: Application
    Filed: August 31, 2007
    Publication date: April 24, 2008
    Inventors: John Falck, Alan Stephenson
  • Securing plug in over-sized holes
    Patent number: 6817076
    Abstract: A method of securing a screw-receiving plug in an over-sized hole preformed in a fixture comprises the steps of: (a) providing at least one piece of a loosely-woven fabric carrying consolidated thereon a quick-setting filler material, which fabric piece is sized to envelop at least circumferentially the plug intended to be used; (b) enveloping the plug circumferentially in the fabric piece; (c) activating the filler material; and (d) inserting the enveloped plug in the hole in a manner such as to ensure filling of the hole by the enveloped plug. On setting, the activated filler material and fabric restrain the plug against rotation when a screw is being driven into the plug thereby to secure the screw in the fixture. The preferred filler material is plaster of Paris.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: November 16, 2004
    Inventor: Alan Stephenson
  • Process for preparing pharmaceutical bulk material having uniform dissolution
    Patent number: 6596307
    Abstract: The present invention provides a process for producing cefaclor crystalline bulk material having a dissolution rate in a capsule of ≧80% in water in 30 minutes. One process route includes reducing the water content of cefaclor dihydrates or bulk material containing cefaclor dihydrate to produce a cefaclor form having a water content ≦2%. The cefaclor having the lower water content can then be rehydrated to a water content from 3.0 to 6.5% without adversely affecting the dissolution rate. An alternative process includes the addition of at least 0.05% of cefaclor related substances to inhibit conversion of the monohydate to the dihydate form.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: July 22, 2003
    Assignee: Eli Lilly and Company
    Inventors: Frank Brown, Jr., Robert Alan Forbes, Arlette Faye Kreager, Michael Vincent Mullen, Gregory Alan Stephenson
  • Olanzapine dihydrate D
    Patent number: 6251895
    Abstract: The present invention provides the novel Dihydrate D 2-methyl-thieno-benzodiazepine and a formulation therefor.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: June 26, 2001
    Assignee: Eli Lilly and Company
    Inventors: Samuel Dean Larsen, John Richard Nichols, Susan Marie Reutzel, Gregory Alan Stephenson
  • Intermediates and process for preparing olanzapine
    Patent number: 6020487
    Abstract: The present invention provides a process for preparing olanzapine and intermediates therefor.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: February 1, 2000
    Assignee: Eli Lilly and Company
    Inventors: Charles Arthur Bunnell, Samuel Dean Larsen, John Richard Nichols, Susan Marie Reutzel, Gregory Alan Stephenson