Abstract: A method and apparatus for replicating a data container of a source storage server at the logical level in an unordered stream of individual data units are described. In certain embodiments, the replication operations can be performed without regard to the differences in geometry of physical persistent storage of the source and destination storage servers and without regard to the differences in data container format of the source and destination storage servers. An initial replication operation of the source data container is performed by transferring the data objects within the source data container to a replica data container in the destination storage server as an unordered stream of individual data units while preserving data object identifiers of the source data objects. Afterwards, incremental replication operations can be performed to capture modifications to the source data container over time after the initial replication operation.

Abstract: The present invention relates to a compound according to formula I and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

Abstract: Various embodiments of a system and method for tracking service requests are described. Embodiments may include call tree generation logic configured to receive multiple request identifiers associated with a respective one of multiple service requests. Each given request identifier may include an origin identifier, a depth value, and a request stack comprising one or more interaction identifiers. The call tree generation logic may also be configured to, based on multiple request identifiers that each include an origin identifier associated with a particular root request, generating a data structure that specifies a hierarchy of services called to fulfill that particular root request. Based on one or more of the interaction identifiers and one or more of the depth values, the generated data structure may specify for each given service of the hierarchy: a parent service that called the given service, and one or more child services called by the given service.

Abstract: The present invention relates to a compound according to formula I and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to, to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

Abstract: Technologies are described herein for event delivery and stream processing utilizing virtual processing agents. Upon receiving an event publication in a queue, a runtime system identifies one or more virtual processing agents that might be interested in, but have not explicitly subscribed to, the published event. Event information of the published event is then delivered to the identified virtual processing agents. Prior to the actual delivery, the runtime system further determines if the virtual processing agents have been activated and activates those processing agents that have not been activated. Based on the received event information, some of the virtual processing agents might decide to explicitly submit subscriptions to receive more events from the queue. The explicit subscriptions will trigger the runtime system to deliver the subscribed events to the processing agents, which might include past events that have been published in the queue before the explicit subscription is received.

Abstract: A biological sample collector 500 comprising a solid support 12 having plural discrete areas (22,24,26,28 FIG. 1) for accepting a biological sample, each area being chemically differentiated, for example by having a different chemical treatment sorbed onto the solid support. An envelope 530 encloses the solid support. A cover portion 520 can cover the biological sample after collection to prevent infection. UV light can be applied to the collected sample to reduce the risk of infection.

Abstract: The present disclosure addresses biologically active formulations for agricultural and other applications that comprise a solid growth substrate that defines an open cell matrix and an active population of one or more microorganisms adhered thereto. The formulation is configured to be applied directly to a plant growth environment and does not require additional isolation and/or processing steps that would separate the microorganisms from the solid growth substrate prior to deployment. The disclosure also addresses related methods.

Abstract: An apparatus configured to assist an operator in connecting electrical connectors. The apparatus includes a first U-shaped cradle and a second U-shaped cradle. Each of the cradles has a contact surface on a front side that is configured to contact a flange on an electrical connector. Each of the cradles also includes a jaw mount configured to mount on a jaw member of a bar clamp.

Abstract: Disclosed are methods of preparing unsaturated carbocyclic compounds through dehydrogenation of corresponding saturated carbocyclic compounds.

Abstract: Disclosed is a method for detecting and quantifying gut flora derived from human faeces, comprising acquiring a solid support containing human faeces; optionally amplifying nucleic acid from the human faeces; and detecting and quantifying the presence of gut flora of interest. Also disclosed is a method for assessing whether a person has type-2 diabetes as well as a kit for detecting and quantifying gut flora from human faeces, comprising a solid support for collecting human faeces; and primer pairs for amplifying 16S rRNA sequence from bacteria of interest.

Abstract: Disclosed is a biological sample collector 500 comprising a solid support 12 having plural discrete areas (22, 24, 26, 28 FIG. 1) for accepting a biological sample, each area being chemically differentiated, for example by having a different chemical treatment sorbed onto the solid support. An envelope 530 encloses the solid support. A cover portion 520 can cover the biological sample after collection to prevent infection. UV light can be applied to the collected sample to reduce the risk of infection.

Abstract: A method and apparatus for replicating a data container of a source storage server at the logical level in an unordered stream of individual data units are described. In certain embodiments, the replication operations can be performed without regard to the differences in geometry of physical persistent storage of the source and destination storage servers and without regard to the differences in data container format of the source and destination storage servers. An initial replication operation of the source data container is performed by transferring the data objects within the source data container to a replica data container in the destination storage server as an unordered stream of individual data units while preserving data object identifiers of the source data objects. Afterwards, incremental replication operations can be performed to capture modifications to the source data container over time after the initial replication operation.

Abstract: The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is —CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl-(C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or —ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.

Abstract: A method and apparatus for replicating a data container of a source storage server at the logical level in an unordered stream of individual data units are described. In certain embodiments, the replication operations can be performed without regard to the differences in geometry of physical persistent storage of the source and destination storage servers and without regard to the differences in data container format of the source and destination storage servers. An initial replication operation of the source data container is performed by transferring the data objects within the source data container to a replica data container in the destination storage server as an unordered stream of individual data units while preserving data object identifiers of the source data objects. Afterwards, incremental replication operations can be performed to capture modifications to the source data container over time after the initial replication operation.

Abstract: Various embodiments of a system and method for tracking service requests are described. Embodiments may include call tree generation logic configured to receive multiple request identifiers associated with a respective one of multiple service requests. Each given request identifier may include an origin identifier, a depth value, and a request stack comprising one or more interaction identifiers. The call tree generation logic may also be configured to, based on multiple request identifiers that each include an origin identifier associated with a particular root request, generating a data structure that specifies a hierarchy of services called to fulfill that particular root request. Based on one or more of the interaction identifiers and one or more of the depth values, the generated data structure may specify for each given service of the hierarchy: a parent service that called the given service, and one or more child services called by the given service.

Abstract: The present disclosure addresses biologically active formulations for agricultural and other applications that comprise a solid growth substrate that defines an open cell matrix and an active population of one or more microorganisms adhered thereto. The formulation is configured to be applied directly to a plant growth environment and does not require additional isolation and/or processing steps that would separate the microorganisms from the solid growth substrate prior to deployment. The disclosure also addresses related methods.

Abstract: The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is —CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl-(C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or —ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.

Abstract: Disclosed are various embodiments for scalable workflow processing. In one embodiment, a plurality of decision applications each embody a functional expression of a corresponding one of a plurality of workflow definitions. Each of the plurality of decision applications is configured to be repeatedly instantiated. A workflow execution application is configured to orchestrate an execution of each one of a plurality of workflow instances. The workflow execution application is in data communication with each instance of a respective one of the plurality of decision applications. Each of the plurality of decision applications is configured to determine a next action to be taken for respective ones of the plurality of workflow instances.

Abstract: Various embodiments of a system and method for tracking service requests are described. Embodiments may include call tree generation logic configured to receive multiple request identifiers associated with a respective one of multiple service requests. Each given request identifier may include an origin identifier, a depth value, and a request stack comprising one or more interaction identifiers. The call tree generation logic may also be configured to, based on multiple request identifiers that each include an origin identifier associated with a particular root request, generating a data structure that specifies a hierarchy of services called to fulfill that particular root request. Based on one or more of the interaction identifiers and one or more of the depth values, the generated data structure may specify for each given service of the hierarchy: a parent service that called the given service, and one or more child services called by the given service.

Abstract: The present invention relates to a compound according to general formula (I) wherein X represents N or CH; R1 is —CN, (C1-C6)alkyl, (C3-C7)cycloalkyl, (3-7 membered)heterocycloalkyl, (5-6 membered)heteroaryl, (C3-C7)cycloalkyl(C1-C4)alkyl, (3-7 membered)heterocycloalkyl-(C1-C4)alkyl or (5-6 membered)heteroaryl-(C1-C4)alkyl; R2 is halogen, cyano, (C1-C4)alkyl or (C3-C7)cycloalkyl; R3 is halogen, cyano, (C1-C4)alkyl, (C1-C4)haloalkyl or (C3-C7)cycloalkyl; R4 is (C1-C4)alkyl or (C1-C4)haloalkyl; R5 is (C1-C6)alkyl, (C3-C7)cycloalkyl, (C1-C6)alkyl-(C3-C7)cycloalkyl, (C3-C7)cycloalkyl-(C1-C6)alkyl, (3-7 membered)heterocycloalkyl, phenyl, (5-6 membered)heteroaryl or —ORa. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds and to intermediates for preparation of said compounds.