Patents by Inventor Alan Upshall

Alan Upshall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment of tumors using transforming growth factor-alpha
    Publication number: 20020077291
    Abstract: The present invention provides pharmaceutical compositions and methods for treating cell proliferative disorders, such as tumors, in a subject, utilizing TGF-&agr; or functional fragments thereof. Optionally, a chemotherapeutic agent is administered in combination with TGF-&agr; or fragments thereof.
    Type: Application
    Filed: September 20, 2001
    Publication date: June 20, 2002
    Inventors: Alan Upshall, Daniel R. Twardzik, Andrzej Sledziewski
  • Expression of higher eucaryotic genes in aspergillus
    Patent number: 4935349
    Abstract: A method for expressing higher eucaryotic genes in Aspergillus through the use of a recombinant plasmid capable of integration into the chromosomal DNA of Aspergillus is disclosed. It is preferred to utilize a transcriptional promoter within a DNA construct contained in the plasmid that is of a DNA sequence encoding an ADH enzyme or a TPI enzyme. Promoters capable of directing the expression of a heterologous gene in Aspergillus, as well as other filamentous fungal genera are also disclosed.
    Type: Grant
    Filed: January 9, 1987
    Date of Patent: June 19, 1990
    Assignee: ZymoGenetics, Inc.
    Inventors: Gary L. McKnight, Alan Upshall