Abstract: The present disclosure describes a surgical system for a valve in an aorta. The surgical system is configured to serve as a temporary valve and/or filter to facilitate maintenance of proper blood flow while also capturing debris of an excised leaflet as needed.

Abstract: Systems and methods for tracking the position of one or more head-mounted display (HMD) system components of an HMD system. The HMD components may carry a plurality of angle sensitive detectors or other types of detectors. The HMD system may be operative to detect corrupted position tracking samples, allowing such samples to be ignored, thereby improving the position tracking process. Control circuitry causes light sources to emit light according a specified pattern, and receives sensor data from the plurality of detectors. Control circuitry may process the sensor data, for example using machine learning or other techniques, to track a position of one or more HMD components.

Abstract: The present disclosure describes a surgical system for a valve in an aorta. The surgical system is configured to serve as a temporary valve and/or filter to facilitate maintenance of proper blood flow while also capturing debris of an excised leaflet as needed.

Abstract: The present disclosure describes a surgical system for an aortic or mitral valve in a heart. The surgical system is configured to pierce, seize, and/or cut a leaflet, and/or facilitate removal of an excised portion of a leaflet.

Abstract: Provided herein are antiviral compounds having the structure of Formula (I) and compositions thereof for use in the treatment of viral infection. In particular, the compounds of Formula (I) are capable of interfering with the export of viral mRNA processing as reflected in the altered accumulation of viral RNA isoforms as well as transport from the nucleus to the cytoplasm. Such compounds show a reduction of HIV, adenovirus and coronavirus infection of cells. The invention provides compounds that may be suitable for the treatment of HIV/AIDS.

Abstract: The present disclosure is a catheter assembly and related method that allows laceration of either a surgical valve or transcatheter valve leaflet to facilitate flow to the coronary arteries during valve in valve interventions.

Abstract: An embodiment of the disclosure is a catheter system configured to be attached to an implanted medical device, such as an implanted valve. The catheter includes an engagement assembly having an elongated member that extends along a central axis, and an engagement member coupled to the elongated member. The engagement assembly has a retracted configuration, where the engagement member is disposed within the channel of the catheter, and an engagement configuration, where the engagement member is disposed outside of the channel and extends outwardly along a direction that is angled with respect to the central axis.

Abstract: A computerized mat cutter machine system includes a mat table having a cutter surface, at least one clamp moveable between a clamped position to secure a matboard to the mat table and a non-clamped position, a cutter head for performing at least one of cutting and finishing a design in the matboard, and a clamp controller bus for communicatively coupling a board controller to a clamp controller of the at least one clamp. The clamp controller bus includes a first bus configured as a dual ended serial differential bus that allows signals to flow from the board controller to the clamp controller, and a second bus configured as an analog bus that allows signals to flow from the clamp controller to the board controller.

Abstract: The present technology relates generally to devices and methods for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A vascular closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the vascular closure device including a plug configured to engage a surface of the puncture; a suture configured coupled to the plug; a locking member configured to engage the plug; and a tamper comprising a first lumen and a second lumen.

Abstract: A blow molded basketball goal having an inner post, an outer post, a rim, and a backboard. The inner post having a top end, a bottom end, a length measured from the top end to the bottom end, and a plurality of protrusions positioned near the bottom end. The outer post having a bottom end, a hollow interior defined by an interior wall, an open top end adapted to receive the inner post, and at least one protuberance on the interior wall. When the inner post is received in the outer post, the plurality of protrusions of the inner post bear against the interior wall of the outer post and the at least one protuberance of the outer post bears against the inner post. The rim is securable to the inner post, and the backboard is securable to the rim. The components are easily removable for disassembly.

Abstract: The present technology relates generally to a method and device for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the closure device including a plug configured to engage a surface of the puncture; a toggle configured to engage an internal surface of the body passageway; an elongate filament configured to associate the plug with the toggle; a locking member configured to engage the plug; and a tamper comprising at least two lumens, wherein a first lumen of the at least two lumens is configured to deliver a pharmaceutical agent to the plug.

Abstract: A deployment instrument for deploying a closure device for sealing a percutaneous puncture in a wall of a body passageway, the deployment instrument including a carrier assembly, wherein the carrier assembly is configured to hold the closure device in a pre-deployment state, and a tensioner assembly, wherein the filament is fixedly attached to the tensioner assembly, wherein the deployment instrument is configured to increase the tension in the filament upon linear movement of the deployment instrument away from the wall of the body passageway when the closure device is anchored to the wall via the anchor such that the tension is gradually increased as the deployment instrument is moved between a first linear distance and a second linear distance greater than the first linear distance from the wall of the body passageway.

Abstract: A blow molded basketball goal having an inner post, an outer post, a rim, and a backboard. The inner post having a top end, a bottom end, a length measured from the top end to the bottom end, and a plurality of protrusions positioned near the bottom end. The outer post having a bottom end, a hollow interior defined by an interior wall, an open top end adapted to receive the inner post, and at least one protuberance on the interior wall. When the inner post is received in the outer post, the plurality of protrusions of the inner post bear against the interior wall of the outer post and the at least one protuberance of the outer post bears against the inner post. The rim is securable to the inner post, and the backboard is securable to the rim. The components are easily removable for disassembly.

Abstract: A blow molded basketball goal having an inner post, an outer post, a rim, and a backboard. The inner post having a top end, a bottom end, a length measured from the top end to the bottom end, and a plurality of protrusions positioned near the bottom end. The outer post having a bottom end, a hollow interior defined by an interior wall, an open top end adapted to receive the inner post, and at least one protuberance on the interior wall. When the inner post is received in the outer post, the plurality of protrusions of the inner post bear against the interior wall of the outer post and the at least one protuberance of the outer post bears against the inner post. The rim is securable to the inner post, and the backboard is securable to the rim.

Abstract: A blow molded basketball goal having an inner post, an outer post, a rim, and a backboard. The inner post having a top end, a bottom end, a length measured from the top end to the bottom end, and a plurality of protrusions positioned near the bottom end. The outer post having a bottom end, a hollow interior defined by an interior wall, an open top end adapted to receive the inner post, and at least one protuberance on the interior wall. When the inner post is received in the outer post, the plurality of protrusions of the inner post bear against the interior wall of the outer post and the at least one protuberance of the outer post bears against the inner post. The rim is securable to the inner post, and the backboard is securable to the rim.

Abstract: The present technology relates generally to a method and device for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the closure device including a plug configured to engage a surface of the puncture; a toggle configured to engage an internal surface of the body passageway; an elongate filament configured to associate the plug with the toggle; a locking member configured to engage the plug; and a tamper comprising at least two lumens, wherein a first lumen of the at least two lumens is configured to deliver a pharmaceutical agent to the plug.

Abstract: The present technology relates generally to a method and device for closing percutaneous punctures, and more particularly to a multi-lumen tamper for such a device. A closure device for sealing a percutaneous puncture in a wall of a body passageway is disclosed, the closure device including a plug configured to engage a surface of the puncture; a toggle configured to engage an internal surface of the body passageway; an elongate filament configured to associate the plug with the toggle; a locking member configured to engage the plug; and a tamper comprising at least two lumens, wherein a first lumen of the at least two lumens is configured to deliver a pharmaceutical agent to the plug.

Abstract: A blow molded toy cycle has a female bearing area with tapered and recess sections. A fork has a corresponding male bearing area that includes a tapered section and an annular protrusion section. A protrusion spaced at a distance from the annular protrusion extends from the shaft and has a surface to contact a top surface of the body to secure the fork when the male and female bearing areas are in contact. The fork has integrally formed tabs that to bend around an axle to form a bearing area for the axle that allows the axle to rotate within the fork. A blow molded pedal attaches to a section of the axle and has a series of ribs disposed between side sections to form a bearing area that allows the pedal to rotate around the axle. Two rear and one front wheels attach to the body and fork respectively.

Abstract: A deployment instrument for deploying a closure device for sealing a percutaneous puncture in a wall of a body passageway, the deployment instrument including a carrier assembly, wherein the carrier assembly is configured to hold the closure device in a pre-deployment state, and a tensioner assembly, wherein the filament is fixedly attached to the tensioner assembly, wherein the deployment instrument is configured to increase the tension in the filament upon linear movement of the deployment instrument away from the wall of the body passageway when the closure device is anchored to the wall via the anchor such that the tension is gradually increased as the deployment instrument is moved between a first linear distance and a second linear distance greater than the first linear distance from the wall of the body passageway.

Abstract: A curtain clip that can be used to hold bunched up curtains to the side, and does not slide vertically because a rubber lining affixed along the inside edge prevents the curtain clip from sliding vertically. The rubber lining prevents the curtain clip from sliding on sheer curtains and other curtains that have a somewhat slippery surface texture.