Abstract: Provided here is a liquid formulation comprising recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) for inhalation by nebulization.

Abstract: Dual and triple therapy combinations of drugs formulated as brittle matrix particles with a high surface area are provided herein. These particle formulations may be used in inhalation or aerosol administration techniques to provide the drug combinations to the lungs. In some aspects, these compositions may be used to treat a respiratory disease or disorder such as asthma or COPD.

Abstract: A device (10) for stretching the foreskin of a subject is disclosed. The device has a body (10) having a passage (14) that extends through the body (10) to a distal end (18). The distal end (18) is adapted to receive a balloon (B). Fluid may be introduced through the passage (14) to cause the balloon (B) to expand. A flow regulating member (20) is positioned across the passage (14) to selectively close the passage (14) to fluid flow.

Abstract: A method of mounting and adjusting a mirror (and a concomitant mount and mirror apparatus) comprising providing a mount surface and mounting a mirror approximately parallel to the mount surface but at an offset angle alpha.

Abstract: A device (10) for stretching the foreskin of a subject is disclosed. The device has a body (10) having a passage (14) that extends through the body (10) to a distal end (18). The distal end (18) is adapted to receive a balloon (B). Fluid may be introduced through the passage (14) to cause the balloon (B) to expand. A flow regulating member (20) is positioned across the passage (14) to selectively close the passage (14) to fluid flow.

Abstract: The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.

Abstract: The present invention relates generally to the field of tissue engineering and more particularly to a method for generating tissue suitable for use in tissue replacement and/or tissue rejuvenation therapy and/or as a source of cell-derived therapeutic or diagnostic agents including proteins and hormones. Even more particularly, the present invention contemplates the use of cell fusion techniques involving single cell, mini-bulk or macro-bulk cell fusion to generate tissue or cells useful for tissue replacement and/or tissue rejuvenation therapy or a range of organs or areas of the body. The resulting tissue or cells may also secrete or generate a range of cytokines, enzymes, hormones and the like which have improved or more efficacious properties relative to analogous molecules produced from non-fused cells. The present invention further provides an apparatus having aspects controlled by data processing means which facilitates the fusion of a pair of cells.

Abstract: A passive focus device including a support rod, an optical assembly translatably mounted on the support rod, and a sealed drive assembly containing a substance that physically changes in response to a temperature change, wherein the drive assembly is configured to move the optical assembly along the support rod based on a physical change of the substance.

Abstract: A passive focus device including a support rod, an optical assembly translatably mounted on the support rod, and a sealed drive assembly containing a substance that physically changes in response to a temperature change, wherein the drive assembly is configured to move the optical assembly along the support rod based on a physical change of the substance.